2AF6
| Crystal structure of Mycobacterium tuberculosis Flavin dependent thymidylate synthase (Mtb ThyX) in the presence of co-factor FAD and substrate analog 5-Bromo-2'-Deoxyuridine-5'-Monophosphate (BrdUMP) | 分子名称: | 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Sampathkumar, P, Turley, S, Ulmer, J.E, Rhie, H.G, Sibley, C.H, Hol, W.G. | 登録日 | 2005-07-25 | 公開日 | 2005-10-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structure of the Mycobacterium tuberculosis Flavin Dependent Thymidylate Synthase (MtbThyX) at 2.0A Resolution. J.Mol.Biol., 352, 2005
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2GQ2
| Mycobacterium tuberculosis ThyX-NADP complex | 分子名称: | GLYCEROL, IODIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Sampathkumar, P, Turley, S, Sibley, C.H, Hol, W.G. | 登録日 | 2006-04-19 | 公開日 | 2006-06-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. J.Mol.Biol., 360, 2006
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