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1XIK
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BU of 1xik by Molmil
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN
分子名称: FE (II) ION, MERCURY (II) ION, PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE
著者Logan, D.T, Su, X.-D, Aberg, A, Regnstrom, K, Hajdu, J, Eklund, H, Nordlund, P.
登録日1996-08-06
公開日1997-03-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.
Structure, 4, 1996
1PFR
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BU of 1pfr by Molmil
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN
分子名称: FE (III) ION, MERCURY (II) ION, PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE
著者Logan, D.T, Su, X.D, Aberg, A, Regnstrom, K, Hajdu, J, Eklund, H, Nordlund, P.
登録日1996-12-03
公開日1997-03-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.
Structure, 4, 1996
4R1R
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BU of 4r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH SUBSTRATE, GDP AND EFFECTOR DTTP FROM ESCHERICHIA COLI
分子名称: GUANOSINE-5'-DIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, ...
著者Eriksson, M, Eklund, H.
登録日1997-07-22
公開日1998-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
3R1R
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BU of 3r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH AMPPNP OCCUPYING THE ACTIVITY SITE FROM ESCHERICHIA COLI
分子名称: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
著者Eriksson, M, Eklund, H.
登録日1997-07-21
公開日1998-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
2R1R
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BU of 2r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI
分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, THYMIDINE-5'-TRIPHOSPHATE
著者Eriksson, M, Eklund, H.
登録日1997-07-21
公開日1998-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
1R1R
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BU of 1r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI
分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
著者Eriksson, M, Eklund, H.
登録日1997-07-15
公開日1998-01-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
4I0J
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BU of 4i0j by Molmil
SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
分子名称: Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-({1-[3-(1H-pyrazol-1-yl)phenyl]cyclohexyl}amino)propyl]acetamide, ZINC ION
著者Yao, N, Brecht, E.
登録日2012-11-16
公開日2013-03-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
TO BE PUBLISHED
4I0H
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BU of 4i0h by Molmil
SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors.
分子名称: (2R)-5-{[(2S,3R)-4-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]amino}-2-hydroxy-5-oxopentanoic acid, Beta-secretase 1
著者Yao, N, Brecht, E.
登録日2012-11-16
公開日2013-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
To be Published
4I0I
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BU of 4i0i by Molmil
SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
分子名称: Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide
著者Yao, N, Brecht, E.
登録日2012-11-16
公開日2013-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
To be Published
4I1F
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BU of 4i1f by Molmil
Structure of Parkin-S223P E3 ligase
分子名称: BARIUM ION, E3 ubiquitin-protein ligase parkin, ZINC ION
著者Lougheed, J.C, Brecht, E, Yao, N.H.
登録日2012-11-20
公開日2013-06-19
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases.
Nat Commun, 4, 2013
4I1H
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BU of 4i1h by Molmil
Structure of Parkin E3 ligase
分子名称: E3 ubiquitin-protein ligase parkin, ZINC ION
著者Lougheed, J.C, Brecht, E, Yao, N.H.
登録日2012-11-20
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases.
Nat Commun, 4, 2013
7R1R
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BU of 7r1r by Molmil
RIBONUCLEOTIDE REDUCTASE E441Q MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
著者Eriksson, M, Eklund, H.
登録日1997-09-17
公開日1998-03-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
6R1R
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BU of 6r1r by Molmil
RIBONUCLEOTIDE REDUCTASE E441D MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
著者Eriksson, M, Eklund, H.
登録日1997-09-17
公開日1998-03-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
2XAX
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BU of 2xax by Molmil
Ribonucleotide reductase Y730NO2Y and Y731A modified R1 subunit of E. coli
分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
著者Yokoyama, K, Uhlin, U, Stubbe, J.
登録日2010-04-01
公開日2010-04-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAW
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BU of 2xaw by Molmil
Ribonucleotide reductase Y730NO2Y and Y731F modified R1 subunit of E. coli
分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
著者Yokoyama, K, Uhlin, U, Stubbe, J.
登録日2010-03-31
公開日2010-04-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAZ
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BU of 2xaz by Molmil
Ribonucleotide reductase Y730NO2Y and C439S modified R1 subunit of E. coli
分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
著者Yokoyama, K, Uhlin, U, Stubbe, J.
登録日2010-04-01
公開日2010-04-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
5R1R
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BU of 5r1r by Molmil
RIBONUCLEOTIDE REDUCTASE E441A MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
著者Eriksson, M, Eklund, H.
登録日1997-09-17
公開日1998-03-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
2XO5
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BU of 2xo5 by Molmil
RIBONUCLEOTIDE REDUCTASE Y731NH2Y MODIFIED R1 SUBUNIT OF E. COLI
分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
著者Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J.
登録日2010-08-09
公開日2010-08-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011
2XO4
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BU of 2xo4 by Molmil
RIBONUCLEOTIDE REDUCTASE Y730NH2Y MODIFIED R1 SUBUNIT OF E. COLI
分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
著者Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J.
登録日2010-08-09
公開日2010-08-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011

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