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Structure of full length human AMPK in complex with a small molecule activator, a thienopyridone derivative (A-769662)
分子名称:	3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, ...
著者	Xiao, B, Sanders, M.J, Carmena, D, Bright, N.J, Haire, L.F, Underwood, E, Patel, B.R, Heath, R.B, Walker, P.A, Hallen, S, Giordanetto, F, Martin, S.R, Carling, D, Gamblin, S.J.
登録日	2013-11-14
公開日	2013-12-25
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (3.924 Å)
主引用文献	Structural Basis of Ampk Regulation by Small Molecule Activators. Nat.Commun., 4, 2013

Structure of full length human AMPK in complex with a small molecule activator, a benzimidazole derivative (991)
分子名称:	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者	Xiao, B, Sanders, M.J, Carmena, D, Bright, N.J, Haire, L.F, Underwood, E, Patel, B.R, Heath, R.B, Walker, P.A, Hallen, S, Giordanetto, F, Martin, S.R, Carling, D, Gamblin, S.J.
登録日	2013-11-14
公開日	2013-12-25
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (3.023 Å)
主引用文献	Structural Basis of Ampk Regulation by Small Molecule Activators. Nat.Commun., 4, 2013

Structure of an active form of mammalian AMPK
分子名称:	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者	Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J.
登録日	2013-11-18
公開日	2013-12-25
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (3.24 Å)
主引用文献	Structure of Mammalian Ampk and its Regulation by Adp Nature, 472, 2011