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Human Sorbitol Dehydrogenase (apo)
分子名称:	Sorbitol dehydrogenase, ZINC ION
著者	Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L.
登録日	2003-06-07
公開日	2004-02-17
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003

Human SDH/NADH/inhibitor complex
分子名称:	4-[2-(HYDROXYMETHYL)PYRIMIDIN-4-YL]-N,N-DIMETHYLPIPERAZINE-1-SULFONAMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Sorbitol dehydrogenase, ...
著者	Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L.
登録日	2003-06-07
公開日	2004-02-17
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003

human SDH/NAD+ complex
分子名称:	NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, human sorbitol dehydrogenase
著者	Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L.
登録日	2003-06-07
公開日	2004-02-17
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003

Glucokinase in complex with activator and glucose
分子名称:	Glucokinase, N,N-dimethyl-5-({2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl}oxy)pyrimidine-2-carboxamide, SODIUM ION, ...
著者	Liu, S.
登録日	2011-05-18
公開日	2011-09-14
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.18 Å)
主引用文献	Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus MEDCHEMCOMM, 2, 2011