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1FZW
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THE STRUCTURAL BASIS OF THE CATALYTIC MECHANISM AND REGULATION OF GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (RMLA). APO ENZYME.
分子名称: GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, SULFATE ION
著者Blankenfeldt, W, Asuncion, M, Lam, J.S, Naismith, J.H.
登録日2000-10-04
公開日2000-12-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA).
EMBO J., 19, 2000
8C0E
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The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase Wzz form a complex in vivo and in vitro
分子名称: ECA polysaccharide chain length modulation protein
著者Weckener, M, Woodward, L.S, Clarke, B.R, Liu, H, Ward, P.N, Le Bas, A, Bhella, D, Whitfield, C, Naismith, J.H.
登録日2022-12-16
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex.
Open Biology, 13, 2023
8BSO
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crystal structure of antibody Fab with SiaLac-amidine-Lys
分子名称: (2~{S})-2-acetamido-6-(2-sulfanylethanimidoylamino)hexanamide, BAR-1 Fab heavy chain, BAR-1 Fab light chain, ...
著者Moynie, L, Naismith, J.H.
登録日2022-11-25
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献crystal structure of antibody Fab with SiaLac-amidine-Lys
To Be Published
8BJZ
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crystal structure of antibody Fab with SiaLac-amidine-Lys
分子名称: (2~{S})-2-acetamido-6-(2-sulfanylethanimidoylamino)hexanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BAR-1 Fab heavy chain, ...
著者Moynie, L, Naismith, J.H.
登録日2022-11-08
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献crystal structure of antibody Fab with SiaLac-amidine-Lys
To Be Published
1O7I
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Crystal structure of a single stranded DNA binding protein
分子名称: SINGLE STRANDED DNA BINDING PROTEIN, SULFATE ION
著者Kerr, I.D, Naismith, J.H.
登録日2002-11-05
公開日2003-06-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein.
EMBO J., 22, 2003
1OI6
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Structure determination of the TMP-complex of EvaD
分子名称: GLYCEROL, PCZA361.16, THYMIDINE-5'-PHOSPHATE
著者Merkel, A.B, Naismith, J.H.
登録日2003-06-09
公開日2004-06-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Position of a Key Tyrosine in Dtdp-4-Keto-6-Deoxy-D-Glucose-5-Epimerase (Evad) Alters the Substrate Profile for This Rmlc-Like Enzyme
J.Biol.Chem., 279, 2004
1KCZ
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BU of 1kcz by Molmil
Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Mg-complex.
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, beta-methylaspartase
著者Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H.
登録日2001-11-12
公開日2001-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
J.Biol.Chem., 277, 2002
1KD0
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Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Apo-structure.
分子名称: 1,2-ETHANEDIOL, beta-methylaspartase
著者Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H.
登録日2001-11-12
公開日2001-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
J.Biol.Chem., 277, 2002
1RQP
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BU of 1rqp by Molmil
Crystal structure and mechanism of a bacterial fluorinating enzyme
分子名称: 5'-fluoro-5'-deoxyadenosine synthase, S-ADENOSYLMETHIONINE
著者Dong, C, Huang, F, Deng, H, Schaffrath, C, Spencer, J.B, O'Hagan, D, Naismith, J.H.
登録日2003-12-06
公開日2004-03-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and mechanism of a bacterial fluorinating enzyme
Nature, 427, 2004
1RQR
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Crystal structure and mechanism of a bacterial fluorinating enzyme, product complex
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-fluoro-5'-deoxyadenosine synthase, METHIONINE
著者Dong, C, Huang, F, Deng, H, Schaffrath, C, Spencer, J.B, O'Hagan, D, Naismith, J.H.
登録日2003-12-07
公開日2004-03-02
最終更新日2022-06-15
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structure and mechanism of a bacterial fluorinating enzyme
Nature, 427, 2004
1SCR
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BU of 1scr by Molmil
HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS
分子名称: CALCIUM ION, CONCANAVALIN A, NICKEL (II) ION
著者Emmerich, C, Helliwell, J.R, Redshaw, M, Naismith, J.H, Harrop, S.J, Raftery, J, Kalb, A.J, Yariv, J, Dauter, Z, Wilson, K.S.
登録日1993-12-06
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A.
Acta Crystallogr.,Sect.D, 50, 1994
1SCS
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BU of 1scs by Molmil
HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS
分子名称: CALCIUM ION, COBALT (II) ION, CONCANAVALIN A
著者Emmerich, C, Helliwell, J.R, Redshaw, M, Naismith, J.H, Harrop, S.J, Raftery, J, Kalb, A.J, Yariv, J, Dauter, Z, Wilson, K.S.
登録日1993-12-06
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A.
Acta Crystallogr.,Sect.D, 50, 1994
1I8T
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BU of 1i8t by Molmil
STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM E.COLI
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-GALACTOPYRANOSE MUTASE
著者Sanders, D.A.R, Staines, A.G, McMahon, S.A, McNeil, M.R, Whitfield, C, Naismith, J.H.
登録日2001-03-16
公開日2001-10-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UDP-galactopyranose mutase has a novel structure and mechanism.
Nat.Struct.Biol., 8, 2001
2AQJ
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BU of 2aqj by Molmil
The structure of tryptophan 7-halogenase (PrnA) suggests a mechanism for regioselective chlorination
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, TRYPTOPHAN, ...
著者Dong, C, Flecks, S, Unversucht, S, Haupt, C, Van Pee, K.-H, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF)
登録日2005-08-18
公開日2005-10-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
Science, 309, 2005
2AR8
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The structure of tryptophan 7-halogenase (PrnA)suggests a mechanism for regioselective chlorination
分子名称: 7-CHLOROTRYPTOPHAN, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Dong, C, Flecks, S, Unversucht, S, Haupt, C, Van Pee, K.H, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF)
登録日2005-08-19
公開日2005-10-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
Science, 309, 2005
2APG
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BU of 2apg by Molmil
The structure of tryptophan 7-halogenase (PrnA)suggests a mechanism for regioselective chlorination
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Dong, C, Flecks, S, Unversucht, S, Haupt, C, Van Pee, K.H, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF)
登録日2005-08-16
公開日2005-10-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
Science, 309, 2005
2ARD
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The structure of tryptophan 7-halogenase (PrnA) suggests a mechanism for regioselective chlorination
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, tryptophan halogenase PrnA
著者Dong, C, Flecks, S, Unversucht, S, Haupt, C, Van Pee, K.H, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF)
登録日2005-08-19
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.
Science, 309, 2005
2BI8
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udp-galactopyranose mutase from Klebsiella pneumoniae with reduced FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-GALACTOPYRANOSE MUTASE
著者Beis, K, Srikannathasan, V, Naismith, J.H.
登録日2005-01-20
公開日2005-05-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Mycobacteria Tuberculosis and Klebsiella Pneumoniae Udp-Galactopyranose Mutase in the Oxidised State and Klebsiella Pneumoniae Udp-Galactopyranose Mutase in the (Active) Reduced State.
J.Mol.Biol., 348, 2005
7BKA
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BU of 7bka by Molmil
Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA) from Pseudomonas aeruginosa in complex with DDD01870824
分子名称: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 4-ethylbenzenesulfonamide, DIMETHYL SULFOXIDE
著者Moynie, L, Naismith, J.H.
登録日2021-01-15
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structures of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA) from Pseudomonas aeruginosa
To Be Published
7BHJ
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Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA) from Pseudomonas aeruginosa in complex with DDD00084774
分子名称: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, ~{N}-[(5-methylfuran-2-yl)methyl]-5-thiophen-2-yl-4~{H}-1,2,4-triazol-3-amine
著者Moynie, L, Naismith, J.H.
登録日2021-01-11
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA)from Pseudomonas aeruginosa in complex with DDD00084774
To Be Published
6TSC
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OphMA I407P complex with SAH
分子名称: GLY-PHE-PRO-TRP-MVA-ILE-MVA-VAL-GLY-VAL-PRO-GLY, Peptide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Song, H, Naismith, J.H.
登録日2019-12-20
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase.
Acs Chem.Biol., 15, 2020
2IYC
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SENP1 native structure
分子名称: SENTRIN-SPECIFIC PROTEASE 1
著者Dong, C, Naismith, J.H.
登録日2006-07-14
公開日2006-08-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Senp1 Native Structure
To be Published
2IYD
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SENP1 covalent complex with SUMO-2
分子名称: SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 2
著者Dong, C, Naismith, J.H.
登録日2006-07-14
公開日2006-08-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Senp1 Native Structure
To be Published
2JKC
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Crystal Structure of E346D of Tryptophan 7-Halogenase (PrnA)
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent tryptophan halogenase PrnA, ...
著者Zhu, X, Naismith, J.H.
登録日2008-08-26
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New insights into the mechanism of enzymatic chlorination of tryptophan.
Angew. Chem. Int. Ed. Engl., 47, 2008
6FCA
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Catalytic subunit HisG from Psychrobacter arcticus ATP phosphoribosyltransferase (HisZG ATPPRT) in complex with PRPP
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ATP phosphoribosyltransferase
著者Alphey, M.S, Ge, Y, Fisher, G, Czekster, C.M, Naismith, J.H, da Silva, R.G.
登録日2017-12-20
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase
Acs Catalysis, 2018

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