2IY5
 
 | | PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS complexed with tRNA and a phenylalanyl-adenylate analog | | 分子名称: | ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ... | | 著者 | Moor, N, Kotik-Kogan, O, Tworowski, D, Sukhanova, M, Safro, M. | | 登録日 | 2006-07-12 | | 公開日 | 2006-09-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end.
Biochemistry, 45, 2006
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3TEG
 | | Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNAPhe with 3,4-Dihydroxy-L-Phenylalanine (L-Dopa) | | 分子名称: | 3,4-DIHYDROXYPHENYLALANINE, Phenylalanyl-tRNA synthetase, mitochondrial | | 著者 | Moor, N, Klipcan, L, Safro, M. | | 登録日 | 2011-08-14 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2044 Å) | | 主引用文献 | Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNA(Phe) with 3,4-Dihydroxy-L-Phenylalanine.
Chem.Biol., 18, 2011
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3TEH
 | | Crystal structure of Thermus thermophilus Phenylalanyl-tRNA synthetase complexed with L-dopa | | 分子名称: | 3,4-DIHYDROXYPHENYLALANINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain | | 著者 | Safro, M, Klipcan, L, Moor, N. | | 登録日 | 2011-08-14 | | 公開日 | 2011-11-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8524 Å) | | 主引用文献 | Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNA(Phe) with 3,4-Dihydroxy-L-Phenylalanine.
Chem.Biol., 18, 2011
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1B70
 | | PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE | | 分子名称: | MAGNESIUM ION, PHENYLALANINE, PHENYLALANYL-TRNA SYNTHETASE | | 著者 | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | | 登録日 | 1999-01-26 | | 公開日 | 2000-02-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue
J.Mol.Biol., 287, 1999
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1B7Y
 | | PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINYL-ADENYLATE | | 分子名称: | ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PROTEIN (PHENYLALANYL-TRNA SYNTHETASE) | | 著者 | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | | 登録日 | 1999-01-26 | | 公開日 | 2000-01-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue.
J.Mol.Biol., 287, 1999
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5MGV
 | | Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2 | | 分子名称: | Phenylalanine--tRNA ligase, mitochondrial | | 著者 | Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. | | 登録日 | 2016-11-22 | | 公開日 | 2017-05-03 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci., 26, 2017
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5MGW
 | | Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2 | | 分子名称: | PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial | | 著者 | Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. | | 登録日 | 2016-11-22 | | 公開日 | 2017-05-03 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci., 26, 2017
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5MGU
 | | Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2 | | 分子名称: | PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial | | 著者 | Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. | | 登録日 | 2016-11-22 | | 公開日 | 2017-05-03 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci., 26, 2017
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5MGH
 | | Crystal structure of pathogenic mutants of human mitochodnrial PheRS | | 分子名称: | PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial | | 著者 | Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. | | 登録日 | 2016-11-21 | | 公開日 | 2017-05-03 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci., 26, 2017
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1JJC
 | | Crystal structure at 2.6A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese | | 分子名称: | ADENOSINE-5'-[PHENYLALANINYL-PHOSPHATE], MANGANESE (II) ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ... | | 著者 | Safro, M.G, Fishman, R, Moor, N, Ankilova, V. | | 登録日 | 2001-07-04 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure at 2.6 A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese.
Acta Crystallogr.,Sect.D, 57, 2001
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3L4G
 | | Crystal structure of Homo Sapiens cytoplasmic Phenylalanyl-tRNA synthetase | | 分子名称: | PHENYLALANINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain | | 著者 | Finarov, I, Moor, N, Kessler, N, Klipcan, L, Safro, M.G. | | 登録日 | 2009-12-20 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of human cytosolic phenylalanyl-tRNA synthetase: evidence for kingdom-specific design of the active sites and tRNA binding patterns.
Structure, 18, 2010
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3TUP
 | | Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state | | 分子名称: | Phenylalanyl-tRNA synthetase, mitochondrial, Thermus thermophilus tRNAPhe | | 著者 | Safro, M, Klipcan, L, Moor, N, Finarov, I, Kessler, N, Sukhanova, M. | | 登録日 | 2011-09-17 | | 公開日 | 2011-11-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active "Open" State.
J.Mol.Biol., 415, 2012
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3HFZ
 | | Crystal structure of Thermus thermophilus Phenylalanyl-tRNA synthetase complexed with m-tyrosine | | 分子名称: | META-TYROSINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain | | 著者 | Klipcan, L, Moor, N, Kessler, N, Safro, M.G. | | 登録日 | 2009-05-13 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
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3CMQ
 | | Crystal structure of human mitochondrial phenylalanine tRNA synthetase | | 分子名称: | ADENOSINE-5'-[PHENYLALANINYL-PHOSPHATE], MAGNESIUM ION, Phenylalanyl-tRNA synthetase, ... | | 著者 | Klipcan, L, Levin, I.L, Kessler, N, Moor, N, Finarov, I, Safro, M. | | 登録日 | 2008-03-24 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The tRNA-Induced Conformational Activation of Human Mitochondrial Phenylalanyl-tRNA Synthetase.
Structure, 16, 2008
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3HFV
 | | Crystal structure of human mitochondrial phenylalanyl-tRNA synthetase complexed with m-tyrosine | | 分子名称: | META-TYROSINE, Phenylalanyl-tRNA synthetase, mitochondrial | | 著者 | Klipcan, L, Moor, N, Kessler, N, Safro, M.G. | | 登録日 | 2009-05-12 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
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2AMC
 | | Crystal structure of Phenylalanyl-tRNA synthetase complexed with L-tyrosine | | 分子名称: | MAGNESIUM ION, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain, ... | | 著者 | Kotik-Kogan, O, Moor, N, Tworowski, D, Safro, M. | | 登録日 | 2005-08-09 | | 公開日 | 2005-12-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis for Discrimination of L-Phenylalanine from L-Tyrosine by Phenylalanyl-tRNA Synthetase
Structure, 13, 2005
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4TVA
 | | Universal Pathway for Post-Transfer Editing Reactions: Insight from Crystal structure of TthPheRS with Puromycine | | 分子名称: | PHENYLALANINE, PUROMYCIN, Phenylalanine--tRNA ligase alpha subunit, ... | | 著者 | Safro, M, Klipcan, L, Tworowski, D, Peretz, M. | | 登録日 | 2014-06-26 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | | 主引用文献 | Universal pathway for posttransfer editing reactions: Insights from the crystal structure of TtPheRS with puromycin.
Proc.Natl.Acad.Sci.USA, 112, 2015
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