5DYY
| Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coquelle, N, Brus, B, Colletier, J.P. | 登録日 | 2015-09-25 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Development of an in-vivo active reversible butyrylcholinesterase inhibitor. Sci Rep, 6, 2016
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5DYT
| Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-methylnaphthalene-2-sulfonamide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coquelle, N, Brus, B, Colletier, J.P. | 登録日 | 2015-09-25 | 公開日 | 2016-10-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Development of an in-vivo active reversible butyrylcholinesterase inhibitor. Sci Rep, 6, 2016
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5DYW
| Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-(2-methoxyethyl)naphthalene-2-sulfonamide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coquelle, N, Brus, B, Colletier, J.P. | 登録日 | 2015-09-25 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Development of an in-vivo active reversible butyrylcholinesterase inhibitor. Sci Rep, 6, 2016
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2R0Z
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2R0W
| PFA2 FAB complexed with Abeta1-8 | 分子名称: | Amyloid beta peptide fragment, IgG2a Fab fragment heavy chain, Fd portion, ... | 著者 | Gardberg, A.S, Dealwis, C. | 登録日 | 2007-08-21 | 公開日 | 2007-10-16 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
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1G96
| HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING | 分子名称: | CHLORIDE ION, CYSTATIN C, GLYCEROL | 著者 | Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Grubb, A, Abrahamson, M, Jaskolski, M. | 登録日 | 2000-11-22 | 公開日 | 2001-04-06 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. Nat.Struct.Biol., 8, 2001
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3EYU
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3EYS
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4TPK
| Human butyrylcholinesterase in complex with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-N-(2-methoxyethyl)-2-naphthamide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coquelle, N, Brus, B, Colletier, J.P, Gobec, S. | 登録日 | 2014-06-07 | 公開日 | 2014-10-22 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor. J.Med.Chem., 57, 2014
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8GVW
| Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class2 | 分子名称: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ... | 著者 | Won, J, Jeong, H, Lee, H.H. | 登録日 | 2022-09-16 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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8GVX
| Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2 | 分子名称: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Won, J, Jeong, H, Lee, H.H. | 登録日 | 2022-09-16 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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6SAM
| Structure of human butyrylcholinesterase in complex with 1-(2,3-dihydro-1H-inden2-yl)piperidin-3-yl N-phenyl carbamate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ... | 著者 | Brazzolotto, X, Kosak, U, Strasek, N, Knez, D, Gobec, S, Nachon, F. | 登録日 | 2019-07-17 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur.J.Med.Chem., 197, 2020
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1I2H
| CRYSTAL STRUCTURE ANALYSIS OF PSD-ZIP45(HOMER1C/VESL-1L)CONSERVED HOMER 1 DOMAIN | 分子名称: | PSD-ZIP45(HOMER-1C/VESL-1L) | 著者 | Irie, K, Nakatsu, T, Mitsuoka, K, Fujiyoshi, Y, Kato, H. | 登録日 | 2001-02-09 | 公開日 | 2002-05-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Homer 1 Family Conserved Region Reveals the Interaction Between the EVH1 Domain and
Own Proline-rich Motif J.Mol.Biol., 318, 2002
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1RPJ
| CRYSTAL STRUCTURE OF D-ALLOSE BINDING PROTEIN FROM ESCHERICHIA COLI | 分子名称: | PROTEIN (PRECURSOR OF PERIPLASMIC SUGAR RECEPTOR), SULFATE ION, ZINC ION, ... | 著者 | Chaudhuri, B, Jones, T.A, Mowbray, S.L. | 登録日 | 1999-02-04 | 公開日 | 1999-02-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of D-allose binding protein from Escherichia coli bound to D-allose at 1.8 A resolution. J.Mol.Biol., 286, 1999
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3O0F
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7X6I
| Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class1 | 分子名称: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Won, J, Jeong, H, Lee, H.H. | 登録日 | 2022-03-07 | 公開日 | 2023-04-26 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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7X6C
| Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class1 | 分子名称: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ... | 著者 | Won, J, Jeong, H, Lee, H.H. | 登録日 | 2022-03-07 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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5LKR
| Human Butyrylcholinesterase complexed with N-Propargyliperidines | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ... | 著者 | Coquelle, N, Knez, D, Colletier, J.P, Gobec, S. | 登録日 | 2016-07-23 | 公開日 | 2016-12-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents. Bioorg. Med. Chem., 25, 2017
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2IQA
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2IPT
| PFA1 Fab Fragment | 分子名称: | ACETAMIDE, IgG2a Fab fragment Heavy Chain, IgG2a Fab fragment Light Chain Kappa | 著者 | Gardberg, A.S, Dealwis, C. | 登録日 | 2006-10-12 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
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2IQ9
| PFA2 FAB fragment, triclinic apo form | 分子名称: | ACETAMIDE, IgG2a Fab fragment PFA2 Kappa light chain, IgG2a Fab fragment PFA2 heavy chain | 著者 | Gardberg, A.S, Dealwis, C. | 登録日 | 2006-10-13 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
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2IPU
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7WAN
| Crystal structure of HaloTag complexed with UL2 | 分子名称: | (R)-[4-(2-azanylhydrazinyl)phenyl]-[2-[2-(2-hexoxyethoxy)ethoxy]ethylamino]methanol, CHLORIDE ION, Haloalkane dehalogenase | 著者 | Pratyush, M, Kang, M, Lee, H, Lee, C, Rhee, H. | 登録日 | 2021-12-14 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.284 Å) | 主引用文献 | A chemical tool for blue light-inducible proximity photo-crosslinking in live cells. Chem Sci, 13, 2022
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7WAM
| Crystal structure of HaloTag complexed with VL1 | 分子名称: | 3-[6-(2-azanylhydrazinyl)-1,3-bis(oxidanylidene)benzo[de]isoquinolin-2-yl]-N-[2-(2-hexoxyethoxy)ethyl]propanamide, CHLORIDE ION, Haloalkane dehalogenase | 著者 | Pratyush, M, Kang, M, Lee, H, Lee, C, Rhee, H. | 登録日 | 2021-12-14 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | A chemical tool for blue light-inducible proximity photo-crosslinking in live cells. Chem Sci, 13, 2022
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5WY8
| Crystal structure of PTP delta Ig1-Ig3 in complex with IL1RAPL1 Ig1-Ig3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | 著者 | Kim, H.M, Won, S.Y, Kim, D. | 登録日 | 2017-01-11 | 公開日 | 2017-11-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate Front Mol Neurosci, 10, 2017
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