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Crystal structure of PPAR-gamma LBD complexed with a partial agonist, analogue of clofibric acid
Descriptor:	(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:	Pochetti, G, Montanari, R, Mazza, F.
Deposit date:	2008-02-27
Release date:	2009-01-13
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists Bioorg.Med.Chem., 20, 2012

Crystal structure of the complex between PPAR-gamma and the agonist LT248 (clofibric acid analogue)
Descriptor:	(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:	Pochetti, G, Montanari, R, Mazza, F.
Deposit date:	2008-02-27
Release date:	2008-12-30
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Crystal Structure of the Peroxisome Proliferator-Activated Receptor gamma (PPARgamma) Ligand Binding Domain Complexed with a Novel Partial Agonist: A New Region of the Hydrophobic Pocket Could Be Exploited for Drug Design J.Med.Chem., 51, 2008