4KXU
| Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate | 分子名称: | 1,2-ETHANEDIOL, D-SORBITOL-6-PHOSPHATE, MAGNESIUM ION, ... | 著者 | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | 登録日 | 2013-05-28 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | 主引用文献 | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
|
|
4KXX
| Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate | 分子名称: | (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | 著者 | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | 登録日 | 2013-05-28 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
|
|
4KXV
| Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 1 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, D-XYLITOL-5-PHOSPHATE, ... | 著者 | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | 登録日 | 2013-05-28 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
|
|
4KXW
| Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 2 | 分子名称: | 1,2-ETHANEDIOL, D-XYLITOL-5-PHOSPHATE, MAGNESIUM ION, ... | 著者 | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | 登録日 | 2013-05-28 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
|
|
3NC0
| Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II) | 分子名称: | DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ... | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | 登録日 | 2010-06-04 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
|
|
3NBY
| Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | 登録日 | 2010-06-04 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
|
|
3NBZ
| Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I) | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | 登録日 | 2010-06-04 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
|
|
3NC1
| Crystal structure of the CRM1-RanGTP complex | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | 登録日 | 2010-06-04 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
|
|
3NS6
| |
3OGZ
| Protein structure of USP from L. major in Apo-form | 分子名称: | GLYCEROL, UDP-sugar pyrophosphorylase | 著者 | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | 登録日 | 2010-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
|
|
3OH3
| Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE -Arabinose | 分子名称: | GLYCEROL, UDP-sugar pyrophosphorylase, [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl dihydrogen diphosphate | 著者 | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | 登録日 | 2010-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
|
|
3OH2
| Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-GALACTOSE | 分子名称: | GALACTOSE-URIDINE-5'-DIPHOSPHATE, GLYCEROL, UDP-sugar pyrophosphorylase | 著者 | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | 登録日 | 2010-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
|
|
3OH4
| Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE Glucose | 分子名称: | GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | 著者 | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F.H, Ficner, R. | 登録日 | 2010-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
|
|
3OH0
| Protein structure of USP from L. major bound to URIDINE-5'-TRIPHOSPHATE | 分子名称: | GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE 5'-TRIPHOSPHATE | 著者 | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | 登録日 | 2010-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
|
|
3OH1
| Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-Galacturonic acid | 分子名称: | (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, GLYCEROL, UDP-sugar pyrophosphorylase | 著者 | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | 登録日 | 2010-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
|
|
3FGR
| Two chain form of the 66.3 kDa protein at 1.8 Angstroem | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Lakomek, K, Dickmanns, A, Ficner, R. | 登録日 | 2008-12-08 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography Bmc Struct.Biol., 9, 2009
|
|
1Y1E
| human formylglycine generating enzyme | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-alpha-formyglycine-generating enzyme, CALCIUM ION | 著者 | Rudolph, M.G, Dickmanns, A, Ficner, R. | 登録日 | 2004-11-18 | 公開日 | 2005-05-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. Cell(Cambridge,Mass.), 121, 2005
|
|
1Y1I
| hyuman formylglycine generating enzyme, reduced form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-alpha-formyglycine-generating enzyme, CALCIUM ION | 著者 | Rudolph, M.G, Dickmanns, A, Ficner, R. | 登録日 | 2004-11-18 | 公開日 | 2005-05-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. Cell(Cambridge,Mass.), 121, 2005
|
|
1Y1G
| Human formylglycine generating enzyme, double sulfonic acid form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-alpha-formyglycine-generating enzyme, CALCIUM ION | 著者 | Rudolph, M.G, Dickmanns, A, Ficner, R. | 登録日 | 2004-11-18 | 公開日 | 2005-05-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. Cell(Cambridge,Mass.), 121, 2005
|
|
1Y1F
| human formylglycine generating enzyme with cysteine sulfenic acid | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-alpha-formyglycine-generating enzyme, CALCIUM ION | 著者 | Rudolph, M.G, Dickmanns, A, Ficner, R. | 登録日 | 2004-11-18 | 公開日 | 2005-05-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. Cell(Cambridge,Mass.), 121, 2005
|
|
1Y1H
| human formylglycine generating enzyme, oxidised Cys refined as hydroperoxide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-alpha-formyglycine-generating enzyme, HYDROGEN PEROXIDE, ... | 著者 | Rudolph, M.G, Dickmanns, A, Ficner, R. | 登録日 | 2004-11-18 | 公開日 | 2005-05-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. Cell(Cambridge,Mass.), 121, 2005
|
|
1Y1J
| human formylglycine generating enzyme, sulfonic acid/desulfurated form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, C-alpha-formyglycine-generating enzyme, ... | 著者 | Rudolph, M.G, Dickmanns, A, Ficner, R. | 登録日 | 2004-11-18 | 公開日 | 2005-05-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. Cell(Cambridge,Mass.), 121, 2005
|
|
1Y4J
| Crystal structure of the paralogue of the human formylglycine generating enzyme | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dickmanns, A, Rudolph, M.G, Ficner, R. | 登録日 | 2004-12-01 | 公開日 | 2005-02-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.864 Å) | 主引用文献 | Crystal Structure of Human pFGE, the Paralog of the C{alpha}-formylglycine-generating Enzyme J.Biol.Chem., 280, 2005
|
|
1YY3
| |
1ZZ0
| Crystal structure of a HDAC-like protein with acetate bound | 分子名称: | ACETATE ION, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... | 著者 | Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. | 登録日 | 2005-06-13 | 公開日 | 2005-11-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
|
|