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Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide
分子名称:	Hepatocyte nuclear factor 4-alpha, MYRISTIC ACID, steroid receptor coactivator-1
著者	Duda, K, Chi, Y.-I, Dhe-paganon, S, Shoelson, S.
登録日	2003-07-11
公開日	2004-06-01
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural Basis for HNF-4alpha Activation by Ligand and Coactivator Binding J.Biol.Chem., 279, 2004

Rsk2 C-terminal Kinase Domain with inhibitor (E)-methyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate
分子名称:	Ribosomal protein S6 kinase alpha-3, SODIUM ION, methyl (2S)-3-{4-amino-7-[(1E)-3-hydroxyprop-1-en-1-yl]-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl}-2-cyanopropanoate
著者	Serafimova, I.M, Pufall, M.A, Krishnan, S, Duda, K, Cohen, M.S, Maglathlin, R.L, McFarland, J.M, Miller, R.M, Frodin, M, Taunton, J.
登録日	2012-01-12
公開日	2012-04-25
最終更新日	2012-05-16
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nat.Chem.Biol., 8, 2012

Rsk2 C-terminal Kinase Domain, (E)-tert-butyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate
分子名称:	Ribosomal protein S6 kinase alpha-3, SODIUM ION, tert-butyl (2S)-3-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyanopropanoate
著者	Serafimova, I.M, Pufall, M.A, Krishnan, S, Duda, K, Cohen, M.S, Maglathlin, R.L, McFarland, J.M, Miller, R.M, Frodin, M, Taunton, J.
登録日	2012-01-12
公開日	2012-04-11
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nat.Chem.Biol., 8, 2012

HNF4a ligand binding domain with bound fatty acid
分子名称:	Hepatocyte nuclear factor 4-alpha, LAURIC ACID
著者	Dhe-Paganon, S, Duda, K, Iwamoto, M, Chi, Y.I, Shoelson, S.E.
登録日	2002-07-22
公開日	2003-07-01
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand J.Biol.Chem., 277, 2002