8SMR
 
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8SNH
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7RJE
 | | Complex III2 from Candida albicans, Inz-5 bound | | 分子名称: | 3-[2-fluoro-5-(trifluoromethyl)phenyl]-7-methyl-1-[(2-methyl-2H-tetrazol-5-yl)methyl]-1H-indazole, Cytochrome b, Cytochrome b-c1 complex subunit 2, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJC
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in intermediate position | | 分子名称: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJD
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in c position | | 分子名称: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJB
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in b position | | 分子名称: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJA
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7RH7
 | | Mycobacterial CIII2CIV2 supercomplex, Telacebec (Q203) bound | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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7RH5
 | | Mycobacterial CIII2CIV2 supercomplex, Inhibitor free | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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7RH6
 | | Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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8F1U
 | | Structure of a 24mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (13.8 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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8F26
 | | Structure of a 60mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-07 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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8F0U
 | | Structure of a 12mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-04 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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8F21
 | | Structure of a 30mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (14.1 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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8F0A
 | | Client-bound structure of a DegP trimer within a 12mer cage | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-02 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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8F1T
 | | Structure of an 18mer DegP cage bound to the client protein hTRF1 | | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | | 登録日 | 2022-11-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (12.1 Å) | | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
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8D4T
 | | Mammalian CIV with GDN bound | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | | 著者 | Di Trani, J, Rubinstein, J. | | 登録日 | 2022-06-02 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of mammalian complex IV inhibition by steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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