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CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991

1L70

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L75

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2020-07-22
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1I6S

T4 LYSOZYME MUTANT C54T/C97A/N101A
分子名称:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者	Kovall, R.A, Baldwin, E.P, Matthews, B.W.
登録日	2001-03-04
公開日	2001-05-09
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme. Protein Sci., 10, 2001

1L58

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	To be Published

1L76

TOLERANCE OF T4 LYSOZYME TO PROLINE SUBSTITUTIONS WITHIN THE LONG INTERDOMAIN ALPHA-HELIX ILLUSTRATES THE ADAPTABILITY OF PROTEINS TO POTENTIALLY DESTABILIZING LESIONS
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Sauer, U, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Tolerance of T4 lysozyme to proline substitutions within the long interdomain alpha-helix illustrates the adaptability of proteins to potentially destabilizing lesions. J.Biol.Chem., 267, 1992

1L63

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L40

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L38

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L55

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L37

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L56

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers, 32, 1992

1L41

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L60

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers, 32, 1992

1L61

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L39

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L62

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L57

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L59

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

3DN1

Chloropentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称:	1-chloro-2,3,4,5,6-pentafluorobenzene, 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, ...
著者	Liu, L, Matthews, B.W.
登録日	2008-07-01
公開日	2008-11-11
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009

3DMZ

Hexafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme, ...
著者	Liu, L, Matthews, B.W.
登録日	2008-07-01
公開日	2008-11-11
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009

3DMV

Free of ligand binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称:	2-HYDROXYETHYL DISULFIDE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者	Liu, L, Matthews, B.W.
登録日	2008-07-01
公開日	2008-11-11
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009

3DN2

Bromopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称:	1-bromo-2,3,4,5,6-pentafluorobenzene, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ...
著者	Liu, L, Matthews, B.W.
登録日	2008-07-01
公開日	2008-11-11
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009

3DN8

Iodopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant (seleno version)
分子名称:	1,2,3,4,5-pentafluoro-6-iodobenzene, 2-HYDROXYETHYL DISULFIDE, BETA-MERCAPTOETHANOL, ...
著者	Liu, L, Matthews, B.W.
登録日	2008-07-01
公開日	2008-11-11
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009

3DN6

1,3,5-trifluoro-2,4,6-trichlorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant
分子名称:	1,3,5-trichloro-2,4,6-trifluorobenzene, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ...
著者	Liu, L, Matthews, B.W.
登録日	2008-07-01
公開日	2008-11-11
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009

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