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Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.
Descriptor:	4-amino-N-(6-methoxypyridin-3-yl)-2-methylquinazoline-8-carboxamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Authors:	Knighton, D.R, Greasley, S.E, Rogers, C.M.-L.
Deposit date:	2010-11-30
Release date:	2011-02-09
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors. Bioorg.Med.Chem.Lett., 21, 2011