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4JEF
Crystal structure of human thymidylate synthase Y202A in inactive conformation.
Descriptor:
SULFATE ION, Thymidylate synthase
Authors:
Tochowicz, A
,
Stroud, R.M
,
Wade, R.C.
Deposit date:
2013-02-26
Release date:
2014-08-20
Last modified:
2015-05-06
Method:
X-RAY DIFFRACTION (2.311 Å)
Cite:
Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
J.Med.Chem., 58, 2015
4LEN
CTX-M-9 in complex with the broad spectrum inhibitor 3-(2- carboxyvinyl)benzo(b)thiophene-2-boronic acid
Descriptor:
(2E)-3-[2-(dihydroxyboranyl)-1-benzothiophen-3-yl]prop-2-enoic acid, Beta-lactamase
Authors:
Tondi, D.
Deposit date:
2013-06-26
Release date:
2014-06-18
Last modified:
2023-09-20
Method:
X-RAY DIFFRACTION (1.5 Å)
Cite:
Targeting Class A and C Serine beta-Lactamases with a Broad-Spectrum Boronic Acid Derivative.
J.Med.Chem., 57, 2014
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220113
数据于2024-05-22公开中