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PPARd complexed with a phenoxyacetic acid partial agonist
分子名称:	IODIDE ION, Peroxisome proliferator-activated receptor delta, [(4-{butyl[2-methyl-4'-(methylsulfanyl)biphenyl-3-yl]sulfamoyl}naphthalen-1-yl)oxy]acetic acid, ...
著者	Lambert, M.H, Evans, K.A, Shearer, B.G, Wisnoski, D.D, Shi, D, Jin, J, Rivero, R.A, Sparks, S.M, Winegar, D.A, Billin, A.N, Britt, C, Way, J.M, Leesnitzer, L.M, Merrihew, R.V.
登録日	2010-10-27
公開日	2011-10-12
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Phenoxyacetic acid PPARd partial agonists for the treatment of type 2 diabetes: synthesis, optimization, and in vivo efficacy Bioorg.Med.Chem.Lett., 21, 2011

Ligand binding domain of PPARgamma complexed with a benzimidazole partial agonist
分子名称:	1-(3,4-dichlorobenzyl)-2-methyl-N-[(1R)-1-phenylpropyl]-1H-benzimidazole-5-carboxamide, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
著者	Lambert, M.H, Xu, R.X.
登録日	2011-06-02
公開日	2012-06-06
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARgamma partial agonist. Bioorg.Med.Chem.Lett., 21, 2011

PPARdelta complexed with an anthranilic acid partial agonist
分子名称:	2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid, IODIDE ION, Peroxisome proliferator-activated receptor delta
著者	Lambert, M.L, Xu, R, Shearer, B.G, Wilson, T.M.
登録日	2008-07-25
公開日	2008-10-07
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Discovery of a novel class of PPARdelta partial agonists Bioorg.Med.Chem.Lett., 18, 2008