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7EJK
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BU of 7ejk by Molmil
Structure of the alpha2A-adrenergic receptor GoA signaling complex bound to oxymetazoline
分子名称: Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, J, Cao, S, Liu, Z, Du, Y.
登録日2021-04-02
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor.
Sci Adv, 8, 2022
7KH0
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BU of 7kh0 by Molmil
Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex
分子名称: Arg-vasopressin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, L, Xu, J, Gao, S, Sun, D, Liu, H, Liu, Z, Du, Y, Zhang, C.
登録日2020-10-19
公開日2021-05-26
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex.
Cell Res., 31, 2021
8I16
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BU of 8i16 by Molmil
Crystal structure of the selenomethionine (SeMet)-derived Cas12g (D513A) mutant
分子名称: Cas12g, ZINC ION
著者Zhang, B, Chen, J, Ye, Y.M, OuYang, S.Y.
登録日2023-01-12
公開日2023-08-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage.
Plos Genet., 19, 2023
8I3Q
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BU of 8i3q by Molmil
Cryo-EM structure of Cas12g-sgRNA binary complex
分子名称: Cas12g, RNA (139-MER), ZINC ION
著者Ouyang, S.Y, Liu, M.X, Li, Z.K.
登録日2023-01-17
公開日2023-09-06
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage.
Plos Genet., 19, 2023
7VYX
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BU of 7vyx by Molmil
Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex
分子名称: Non-target DNA strand, Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, Target DNA strand, ...
著者Zhang, B, Lin, J.Y, Perculija, V, OuYang, S.Y.
登録日2021-11-15
公開日2022-11-02
最終更新日2023-06-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system
Nucleic Acids Res., 50, 2022
7WZ4
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BU of 7wz4 by Molmil
Structure of an orphan GPCR-G protein signaling complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Xu, J, Chen, G, Liu, Z, Du, Y.
登録日2022-02-17
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.
Nat Commun, 13, 2022
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