2ZX9
 
 | | alpha-L-fucosidase complexed with inhibitor, B4 | | 分子名称: | (2S)-2-cyclopentyl-2-phenyl-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}ethanamide, Alpha-L-fucosidase, putative | | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2008-12-22 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZX6
 | | alpha-L-fucosidase complexed with inhibitor, F10-1C | | 分子名称: | 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide, Alpha-L-fucosidase, putative | | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2008-12-19 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
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3PJG
 | | Crystal structure of UDP-glucose dehydrogenase from Klebsiella pneumoniae complexed with product UDP-glucuronic acid | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-10 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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2ZE3
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3PID
 | | The apo-form UDP-glucose 6-dehydrogenase with a C-terminal six-histidine tag | | 分子名称: | UDP-glucose 6-dehydrogenase | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-06 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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3PLN
 | | Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with UDP-glucose | | 分子名称: | UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-15 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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3PLR
 | | Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with NADH and UDP-glucose | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-15 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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3EX8
 | | Complex structure of bacillus subtilis RibG reduction mechanism in riboflavin biosynthesis | | 分子名称: | Riboflavin biosynthesis protein ribD, ZINC ION, [(2R,3S,4R,5E)-5-[(5-amino-2,6-dioxo-3H-pyrimidin-4-yl)imino]-2,3,4-trihydroxy-pentyl] dihydrogen phosphate | | 著者 | Chen, S.C, Lin, Y.H, Yu, H.C, Liaw, S.H. | | 登録日 | 2008-10-16 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Complex structure of Bacillus subtilis RibG: the reduction mechanism during riboflavin biosynthesis.
J.Biol.Chem., 284, 2009
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7QQR
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7QQV
 | | SpCas9 bound to FANCF off-target3 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target3 non-target strand, FANCF off-target3 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QR5
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7QQO
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7QQP
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7QQS
 | | SpCas9 bound to FANCF on-target DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF on-target non-target strand, FANCF on-target target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QQQ
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7QQU
 | | SpCas9 bound to FANCF off-target2 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QQT
 | | SpCas9 bound to FANCF off-target1 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QQX
 | | SpCas9 bound to FANCF off-target5 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QR8
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7QR0
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7QQZ
 | | SpCas9 bound to FANCF off-target7 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QQW
 | | SpCas9 bound to FANCF off-target4 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QR1
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7QR7
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7ZO1
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