7ALM
 
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7AIA
 | | Complex of human GDAP1 with hexadecanedioic acid | | 分子名称: | ETHANOL, GLYCEROL, Ganglioside-induced differentiation-associated protein 1, ... | | 著者 | Nguyen, G.T.T, Sutinen, A, Kursula, P. | | 登録日 | 2020-09-26 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations.
Front Mol Biosci, 7, 2020
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7B2G
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6TU2
 | | Crystal structure of rat annexin A11 | | 分子名称: | Annexin, CALCIUM ION | | 著者 | Raasakka, A, Lillebostad, P, Vedeler, A, Kursula, P. | | 登録日 | 2020-01-01 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment.
Biomolecules, 10, 2020
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6GZL
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6GZJ
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6HYF
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2BZN
 | | Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP | | 分子名称: | GMP REDUCTASE 2, INOSINIC ACID | | 著者 | Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J. | | 登録日 | 2005-08-19 | | 公開日 | 2005-09-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
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2XMI
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with citrate | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, CITRATE ANION, ... | | 著者 | Myllykoski, M, Kursula, P. | | 登録日 | 2010-07-28 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation.
Plos One, 7, 2012
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2Y3X
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with sulfate | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, GLYCEROL, ... | | 著者 | Myllykoski, M, Kursula, P. | | 登録日 | 2011-01-04 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation.
Plos One, 7, 2012
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2YDB
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic NADP | | 分子名称: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Myllykoski, M, Kursula, P. | | 登録日 | 2011-03-18 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active- Site Ligand Binding and Molecular Conformation.
Plos One, 7, 2012
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2YDD
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic AMP | | 分子名称: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, ADENOSINE-2'-MONOPHOSPHATE | | 著者 | Myllykoski, M, Kursula, P. | | 登録日 | 2011-03-18 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active- Site Ligand Binding and Molecular Conformation.
Plos One, 7, 2012
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2YDC
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5O99
 | | Unconventional SH3 domain from the postsynaptic density scaffold protein Shank3 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SH3 and multiple ankyrin repeat domains protein 3 | | 著者 | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | | 登録日 | 2017-06-16 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (0.871 Å) | | 主引用文献 | Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution.
Biochem. Biophys. Res. Commun., 490, 2017
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5OVV
 | | PDZ domain from rat Shank3 bound to the C terminus of ProSAPiP1 | | 分子名称: | Leucine zipper putative tumor suppressor 3, SH3 and multiple ankyrin repeat domains protein 3, THIOCYANATE ION | | 著者 | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | | 登録日 | 2017-08-29 | | 公開日 | 2018-03-07 | | 最終更新日 | 2018-07-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.
J. Neurochem., 145, 2018
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5OVA
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5OVP
 | | PDZ domain from rat Shank3 bound to the C terminus of CIRL | | 分子名称: | Adhesion G protein-coupled receptor L1, SH3 and multiple ankyrin repeat domains protein 3 | | 著者 | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | | 登録日 | 2017-08-29 | | 公開日 | 2018-03-07 | | 最終更新日 | 2018-07-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.
J. Neurochem., 145, 2018
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5OVC
 | | PDZ domain from rat Shank3 bound to the C terminus of GKAP | | 分子名称: | CHLORIDE ION, GKAP C terminus, synthetic peptide, ... | | 著者 | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | | 登録日 | 2017-08-28 | | 公開日 | 2018-03-07 | | 最終更新日 | 2018-07-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.
J. Neurochem., 145, 2018
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6S2M
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6S2S
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6SID
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6SIE
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6SIB
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6STS
 | | Human myelin protein P2 mutant R30Q | | 分子名称: | Myelin P2 protein, PALMITIC ACID, SULFATE ION | | 著者 | Ruskamo, S, Lehtimaki, M, Kursula, P. | | 登録日 | 2019-09-11 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6TA0
 | | Human NAMPT in complex with nicotinic acid and phosphoribosyl pyrophosphate | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GLYCEROL, NICOTINIC ACID, ... | | 著者 | Houry, D, Raasakka, A, Kursula, P, Ziegler, M. | | 登録日 | 2019-10-29 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Identification of structural determinants of NAMPT activity and substrate selectivity
To Be Published
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