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Solution NMR Structure of TolAIII Bound to a Peptide Derived from the N-terminus of TolB
分子名称:	Cell envelope integrity/translocation protein TolA, TolBp
著者	Kleanthous, C, Redfield, C, Rajasekar, K, Holmes, P.
登録日	2019-06-26
公開日	2020-03-25
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism. Nat Commun, 11, 2020

4V5K

Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome
分子名称:	16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者	Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V.
登録日	2010-05-29
公開日	2014-07-09
最終更新日	2019-07-31
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3. Nat.Struct.Mol.Biol., 17, 2010

8ODT

Structure of TolQR complex from E.coli
分子名称:	Tol-Pal system protein TolQ, Tol-Pal system protein TolR
著者	Webby, M.N, Kleanthous, C, Press, C.E.
登録日	2023-03-09
公開日	2023-11-01
最終更新日	2023-11-29
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Tunable force transduction through the Escherichia coli cell envelope. Proc.Natl.Acad.Sci.USA, 120, 2023

1AYI

COLICIN E7 IMMUNITY PROTEIN IM7
分子名称:	COLICIN E IMMUNITY PROTEIN 7
著者	Dennis, C.A, Pauptit, R.A, Wallis, R, James, R, Moore, G.R, Kleanthous, C.
登録日	1997-11-04
公開日	1998-01-28
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity. Biochem.J., 333 ( Pt 1), 1998

6THK

Structural mechanism of pyocin S5 import into Pseudomonas aeruginosa
分子名称:	GLYCEROL, Pyocin S5, ZINC ION
著者	Behrens, H.M, Kleanthous, C, Lowe, E.D.
登録日	2019-11-20
公開日	2020-03-04
最終更新日	2020-03-25
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport. Mbio, 11, 2020

3O0E

Crystal structure of OmpF in complex with colicin peptide OBS1
分子名称:	Colicin-E9, Porin OmpF, octyl beta-D-glucopyranoside
著者	Wojdyla, J.A, Housden, N.G, Korczynska, J, Grishkovskaya, I, Kirkpatrick, N, Brzozowski, A.M, Kleanthous, C.
登録日	2010-07-19
公開日	2010-12-08
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (3.01 Å)
主引用文献	Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF. Proc.Natl.Acad.Sci.USA, 107, 2010

4JML

Crystal structure of the TolB(P201C)-ColicinE9 TBE peptide(A33C) complex.
分子名称:	CALCIUM ION, Colicin-E9, Protein TolB
著者	Wojdyla, J.A, Klein, A, Kleanthous, C.
登録日	2013-03-14
公開日	2013-07-17
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF. Science, 340, 2013

3U43

Crystal structure of the colicin E2 DNase-Im2 complex
分子名称:	CALCIUM ION, Colicin-E2, Colicin-E2 immunity protein, ...
著者	Wojdyla, J.A, Kleanthous, C.
登録日	2011-10-07
公開日	2012-03-21
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.72 Å)
主引用文献	Structure of the Ultra-High-Affinity Colicin E2 DNase-Im2 Complex. J.Mol.Biol., 417, 2012

5ODW

Structure of the FpvAI-pyocin S2 complex
分子名称:	Ferripyoverdine receptor, Pyocin-S2, SULFATE ION
著者	White, P, Joshi, A, Kleanthous, C.
登録日	2017-07-06
公開日	2017-11-08
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Exploitation of an iron transporter for bacterial protein antibiotic import. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

4UHQ

Crystal structure of the pyocin AP41 DNase
分子名称:	CITRIC ACID, LARGE COMPONENT OF PYOCIN AP41, NICKEL (II) ION
著者	Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C.
登録日	2015-03-25
公開日	2015-08-05
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa J.Mol.Biol., 427, 2015

4UDM

Crystal structure of Im3 in complex with Y52A mutant of E3RNase
分子名称:	CALCIUM ION, CHLORIDE ION, COLICIN-E3, ...
著者	Sharma, A, Kleanthous, C.
登録日	2014-12-10
公開日	2016-01-13
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.96 Å)
主引用文献	Consequences of Inducing Intrinsic Disorder in a High-Affinity Protein-Protein Interaction. J.Am.Chem.Soc., 137, 2015

4UHP

Crystal structure of the pyocin AP41 DNase-Immunity complex
分子名称:	BACTERIOCIN IMMUNITY PROTEIN, LARGE COMPONENT OF PYOCIN AP41
著者	Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C.
登録日	2015-03-25
公開日	2015-08-05
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa J.Mol.Biol., 427, 2015

1BXI

CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9
分子名称:	NICKEL (II) ION, PHOSPHATE ION, PROTEIN (COLICIN E9 IMMUNITY PROTEIN), ...
著者	Kuhlmann, U.C, Kleanthous, C, James, R, Moore, G.R, Hemmings, A.M.
登録日	1998-10-04
公開日	1999-10-04
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Crystal Structure of the E.Coli Colicin E9 DNase Domain With its Cognate Immunity Protein Im9 Thesis, 1998

1IMQ

COLICIN E9 IMMUNITY PROTEIN IM9, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称:	IM9
著者	Osborne, M.J, Breeze, A.L, Lian, L.Y, Reilly, A, James, R, Kleanthous, C, Moore, G.R.
登録日	1996-05-30
公開日	1997-07-07
最終更新日	2022-02-23
実験手法	SOLUTION NMR
主引用文献	Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9. Biochemistry, 35, 1996

1IMP

COLICIN E9 IMMUNITY PROTEIN IM9, NMR, 21 STRUCTURES
分子名称:	IM9
著者	Osborne, M.J, Breeze, A.L, Lian, L.-Y, Reilly, A, James, R, Kleanthous, C, Moore, G.R.
登録日	1996-05-30
公開日	1997-09-17
最終更新日	2022-02-23
実験手法	SOLUTION NMR
主引用文献	Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9. Biochemistry, 35, 1996

1V15

CRYSTAL STRUCTURE OF THE COLICIN E9, MUTANT HIS103ALA, IN COMPLEX WITH ZN+2 AND DSDNA (RESOLUTION 2.4A)
分子名称:	5'-D(GPCPGPAPTPCPGPCP)-3', COLICIN E9, ZINC ION
著者	Mate, M.J, Kleanthous, C.
登録日	2004-04-06
公開日	2004-06-23
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases J.Biol.Chem., 279, 2004

1V14

Crystal Structure of the Colicin E9, mutant His103Ala, in complex with Mg+2 and dsDNA (resolution 2.9A)
分子名称:	5'-D(GPCPGPAPTPCPGPCP)-3', COLICIN E9, MAGNESIUM ION
著者	Mate, M.J, Kleanthous, C.
登録日	2004-04-06
公開日	2004-06-23
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases J.Biol.Chem., 279, 2004

1V13

CRYSTAL STRUCTURE OF THE MUTANT HIS103ALA OF THE COLICIN E9 DNASE DOMAIN IN COMPLEX WITH ZN+2 (2.0 ANGSTROMS)
分子名称:	COLICIN E9, ZINC ION
著者	Mate, M.J, Kleanthous, C.
登録日	2004-04-06
公開日	2004-06-23
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases J.Biol.Chem., 279, 2004

5FRF

Solution structure of reduced and zinc-bound RsrA
分子名称:	ANTI-SIGMA FACTOR RSRA, ZINC ION
著者	Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C.
登録日	2015-12-17
公開日	2016-08-03
最終更新日	2019-10-23
実験手法	SOLUTION NMR
主引用文献	The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core. Nat.Commun., 7, 2016

5FRH

Solution structure of oxidised RsrA
分子名称:	ANTI-SIGMA FACTOR RSRA
著者	Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C.
登録日	2015-12-17
公開日	2016-08-03
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core. Nat.Commun., 7, 2016

7NG8

Trimeric efflux pump Klebsiella TolC in complex with KlebC
分子名称:	Klebicin C activity, Outer membrane channel protein
著者	Webby, M.N, Housden, N.G, Kleanthous, C.
登録日	2021-02-08
公開日	2021-06-30
最終更新日	2021-10-13
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Toxin import through the antibiotic efflux channel TolC. Nat Commun, 12, 2021

7NG9

Trimeric efflux pump Klebsiella TolC
分子名称:	Outer membrane channel protein
著者	Webby, M.N, Housden, N.G, Kleanthous, C.
登録日	2021-02-08
公開日	2021-06-30
最終更新日	2021-10-13
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Toxin import through the antibiotic efflux channel TolC. Nat Commun, 12, 2021

7NNA

Toxin Import Through the Antibiotic Efflux Channel TolC
分子名称:	Klebicin C activity
著者	Lowe, E.D, Kleanthous, C, Housden, N.G.
登録日	2021-02-24
公開日	2021-07-07
最終更新日	2021-10-13
実験手法	X-RAY DIFFRACTION (1.901 Å)
主引用文献	Toxin import through the antibiotic efflux channel TolC. Nat Commun, 12, 2021

4QAY

Crystal structure of TamA POTRA domains
分子名称:	PHOSPHATE ION, Translocation and assembly module TamA
著者	Wojdyla, J.A, Mosbahi, K, Walker, D, Kleanthous, C.
登録日	2014-05-06
公開日	2015-11-18
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Recognition of autotransporter passenger domains by the TAM complex To be Published

1FSJ

CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN
分子名称:	COLICIN E9, PHOSPHATE ION, ZINC ION
著者	Kuhlmann, U.C, Pommer, A.J, Moore, G.R, James, R, Kleanthous, C, Hemmings, A.M.
登録日	2000-09-11
公開日	2003-06-17
最終更新日	2022-12-21
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structure of the E9 DNase domain in comparison with the inhibited structure of the E9 DNase/Im9 complex To be Published

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