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2HWY
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BU of 2hwy by Molmil
Structure of PIN domain of human SMG5.
分子名称: Protein SMG5
著者Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
登録日2006-08-02
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006
1JN5
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BU of 1jn5 by Molmil
Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor
分子名称: FG-repeat, TAP, p15
著者Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E.
登録日2001-07-23
公開日2001-10-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
1JKG
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BU of 1jkg by Molmil
Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor
分子名称: TAP, p15
著者Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E.
登録日2001-07-12
公開日2001-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
1VYN
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BU of 1vyn by Molmil
STRUCTURE AND NUCLEIC ACID BINDING OF THE DROSOPHILA ARGONAUTE2 PAZ DOMAIN
分子名称: ARGONAUTE2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-05-03
公開日2004-05-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain.
Nature, 426, 2003
3ZHE
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BU of 3zhe by Molmil
Structure of the C. elegans SMG5-SMG7 complex
分子名称: NONSENSE-MEDIATED MRNA DECAY PROTEIN, PROTEIN SMG-7
著者Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2012-12-21
公開日2013-02-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献An Unusual Arrangement of Two 14-3-3-Like Domains in the Smg5-Smg7 Heterodimer is Required for Efficient Nonsense-Mediated Mrna Decay.
Genes Dev., 27, 2013
4A54
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BU of 4a54 by Molmil
Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6
分子名称: EDC3, MRNA DECAPPING COMPLEX SUBUNIT 2
著者Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R.
登録日2011-10-24
公開日2012-02-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
4A53
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BU of 4a53 by Molmil
Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6
分子名称: EDC3
著者Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R.
登録日2011-10-24
公開日2012-02-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
4C0G
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BU of 4c0g by Molmil
Structure of the NOT-box domain of human CNOT3
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
著者Boland, A, Chen, Y, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2013-08-01
公開日2013-10-09
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
1UW4
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BU of 1uw4 by Molmil
The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3
分子名称: BETA-MERCAPTOETHANOL, REGULATOR OF NONSENSE TRANSCRIPTS 2, UPF3X
著者Kadlec, J, Izaurralde, E, Cusack, S.
登録日2004-01-29
公開日2004-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Structural Basis for the Interaction between Nonsense-Mediated Mrna Decay Factors Upf2 and Upf3
Nat.Struct.Mol.Biol., 11, 2004
2VXG
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BU of 2vxg by Molmil
Crystal structure of the conserved C-terminal region of Ge-1
分子名称: CG6181-PA, ISOFORM A
著者Jinek, M, Eulalio, A, Lingel, A, Helms, S, Conti, E, Izaurralde, E.
登録日2008-07-04
公開日2008-09-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The C-Terminal Region of Ge-1 Presents Conserved Structural Features Required for P-Body Localization.
RNA, 14, 2008
5ONA
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BU of 5ona by Molmil
Drosophila Bag-of-marbles CBM peptide bound to human CAF40-CNOT1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 9, CHLORIDE ION, ...
著者Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O.
登録日2017-08-03
公開日2017-12-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA, 24, 2018
5ONB
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BU of 5onb by Molmil
Drosophila Bag-of-marbles CBM peptide bound to human CAF40
分子名称: CCR4-NOT transcription complex subunit 9, GLYCEROL, Protein bag-of-marbles
著者Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O.
登録日2017-08-03
公開日2017-12-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA, 24, 2018
4BWK
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BU of 4bwk by Molmil
Structure of Neurospora crassa PAN3 pseudokinase
分子名称: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E.
登録日2013-07-04
公開日2013-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
4BWX
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BU of 4bwx by Molmil
Structure of Neurospora crassa PAN3 pseudokinase mutant
分子名称: MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E.
登録日2013-07-04
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
4BWP
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BU of 4bwp by Molmil
Structure of Drosophila Melanogaster PAN3 pseudokinase
分子名称: AMP PHOSPHORAMIDATE, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3
著者Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E.
登録日2013-07-03
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
2WBR
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BU of 2wbr by Molmil
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
分子名称: GW182
著者Eulalio, A, Tritschler, F, Buettner, R, Weichenrieder, O, Izaurralde, E, Truffault, V.
登録日2009-03-03
公開日2009-03-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Rrm Domain in Gw182 Proteins Contributes to Mirna-Mediated Gene Silencing.
Nucleic Acids Res., 37, 2009
4CZV
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BU of 4czv by Molmil
Structure of the Neurospora crassa Pan2 WD40 domain
分子名称: CHLORIDE ION, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2
著者Peter, D, Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2014-04-22
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4CZW
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BU of 4czw by Molmil
Structure of the Neurospora crassa Pan2 catalytic unit (protease and nuclease domain)
分子名称: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ZINC ION
著者Christie, M, Izaurralde, E, Weichenrieder, O.
登録日2014-04-22
公開日2014-06-04
最終更新日2014-07-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4CZY
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BU of 4czy by Molmil
Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ...
著者Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2014-04-22
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4CZX
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Complex of Neurospora crassa PAN2 (WD40) with PAN3 (C-TERM)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ...
著者Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2014-04-22
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4D0K
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BU of 4d0k by Molmil
Complex of Chaetomium thermophilum PAN2 (WD40-CS1) with PAN3 (C-term)
分子名称: A-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN
著者Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2014-04-28
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4GMJ
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BU of 4gmj by Molmil
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
4GML
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Crystal structure of human NOT1 MIF4G domain
分子名称: CCR4-NOT transcription complex subunit 1
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
4C0E
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BU of 4c0e by Molmil
Structure of the NOT1 superfamily homology domain from Chaetomium thermophilum
分子名称: NOT1
著者Chen, Y, Boland, A, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2013-08-01
公開日2013-10-09
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
4C0D
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Structure of the NOT module of the human CCR4-NOT complex (CNOT1-CNOT2-CNOT3)
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
著者Raisch, T, Jonas, S, Boland, A, Chen, Y, Izaurralde, E, Weichenrieder, O.
登録日2013-08-01
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013

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