1DJR
| HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH M-CARBOXYPHENYL-ALPHA-D-GALACTOSE | Descriptor: | BENZOIC ACID, GLYCEROL, HEAT-LABILE ENTEROTOXIN, ... | Authors: | Minke, W.E, Pickens, J, Merritt, E.A, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | Deposit date: | 1999-12-03 | Release date: | 2000-06-30 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of m-carboxyphenyl-alpha-D-galactopyranoside complexed to heat-labile enterotoxin at 1.3 A resolution: surprising variations in ligand-binding modes. Acta Crystallogr.,Sect.D, 56, 2000
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1P2P
| STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 AT 2.6 ANGSTROMS RESOLUTION AND COMPARISON WITH BOVINE PHOSPHOLIPASE A2 | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Dijkstra, B.W, Renetseder, R, Kalk, K.H, Hol, W.G.J, Drenth, J. | Deposit date: | 1983-06-27 | Release date: | 1983-09-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2. J.Mol.Biol., 168, 1983
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1PHH
| CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE | Descriptor: | 3,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE | Authors: | Schreuder, H.A, Drenth, J. | Deposit date: | 1987-11-04 | Release date: | 1988-04-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate. J.Mol.Biol., 199, 1988
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1EVZ
| CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH NAD | Descriptor: | GLYCEROL-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PENTADECANE | Authors: | Suresh, S, Turley, S, Opperdoes, F.R, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2000-04-21 | Release date: | 2001-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana. Structure Fold.Des., 8, 2000
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1EVY
| CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE | Descriptor: | GLYCEROL-3-PHOSPHATE DEHYDROGENASE, PENTADECANE | Authors: | Suresh, S, Turley, S, Opperdoes, F.R, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2000-04-20 | Release date: | 2001-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana. Structure Fold.Des., 8, 2000
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1F2J
| CRYSTAL STRUCTURE ANALYSIS OF ALDOLASE FROM T. BRUCEI | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE, GLYCOSOMAL | Authors: | Chudzik, D.M, Michels, P.A, De Walque, S, Hol, W.G.J. | Deposit date: | 2000-05-25 | Release date: | 2000-07-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases. J.Mol.Biol., 300, 2000
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1FD7
| HEAT-LABILE ENTEROTOXIN B-PENTAMER WITH BOUND LIGAND BMSC001 | Descriptor: | HEAT-LABILE ENTEROTOXIN B CHAIN, N-BENZYL-3-(ALPHA-D-GALACTOS-1-YL)-BENZAMIDE | Authors: | Fan, E, Merritt, E.A, Pickens, J, Ahn, M, Hol, W.G.J. | Deposit date: | 2000-07-19 | Release date: | 2000-08-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta Crystallogr.,Sect.D, 57, 2001
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1FM2
| THE 2 ANGSTROM CRYSTAL STRUCTURE OF CEPHALOSPORIN ACYLASE | Descriptor: | GLUTARYL 7-AMINOCEPHALOSPORANIC ACID ACYLASE | Authors: | Kim, Y, Yoon, K.H, Khang, Y, Turley, S, Hol, W.G.J. | Deposit date: | 2000-08-15 | Release date: | 2001-08-15 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0 A crystal structure of cephalosporin acylase. Structure Fold.Des., 8, 2000
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1G3S
| CYS102SER DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1G3Y
| ARG80ALA DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, ZINC ION | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1FX7
| CRYSTAL STRUCTURE OF THE IRON-DEPENDENT REGULATOR (IDER) FROM MYCOBACTERIUM TUBERCULOSIS | Descriptor: | COBALT (II) ION, IRON-DEPENDENT REPRESSOR IDER, SULFATE ION | Authors: | Feese, M.D, Ingason, B.P, Goranson-Siekierke, J, Holmes, R.K, Hol, W.J.G. | Deposit date: | 2000-09-25 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain. J.Biol.Chem., 276, 2001
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1FWZ
| GLU20ALA DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-09-25 | Release date: | 2001-09-25 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1G3T
| CYS102SER DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1G3W
| CD-CYS102SER DTXR | Descriptor: | CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1GYQ
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1LVL
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1MC0
| Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains | Descriptor: | 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE | Authors: | Martinez, S, Wu, A, Glavas, N, Tang, X, Turley, S, Hol, W, Beavo, J. | Deposit date: | 2002-08-04 | Release date: | 2002-10-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding. Proc.Natl.Acad.Sci.USA, 99, 2002
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1GYP
| CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN AND A NEW POSITION FOR THE INORGANIC PHOSPHATE BINDING SITE | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | Authors: | Kim, H, Feil, I.K, Verlinde, C.L.M.J, Petra, P.H, Hol, W.G.J. | Deposit date: | 1995-08-01 | Release date: | 1995-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site. Biochemistry, 34, 1995
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1HXI
| AN UNEXPECTED EXTENDED CONFORMATION FOR THE THIRD TPR MOTIF OF THE PEROXIN PEX5 FROM TRYPANOSOMA BRUCEI | Descriptor: | MAGNESIUM ION, PEROXISOME TARGETING SIGNAL 1 RECEPTOR PEX5 | Authors: | Kumar, A, Roach, C, Hirsh, I.S, Turley, S, deWalque, S, Michels, P.A.M, Hol, W.G.J. | Deposit date: | 2001-01-15 | Release date: | 2001-03-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei. J.Mol.Biol., 307, 2001
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1I33
| LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS | Descriptor: | GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, N-1,2,3,4-TETRAHYDRONAPHTH-1-YL-2'-[3,5-DIMETHOXYBENZAMIDO]-2'-DEOXY-ADENOSINE | Authors: | Suresh, S, Bressi, J.C, Kennedy, K.J, Verlinde, C.L.M.J, Gelb, M.H, Hol, W.G.J. | Deposit date: | 2001-02-12 | Release date: | 2001-10-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors. J.Mol.Biol., 309, 2001
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1I32
| LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS | Descriptor: | GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, N-NAPHTHALEN-1-YLMETHYL-2'-[3,5-DIMETHOXYBENZAMIDO]-2'-DEOXY-ADENOSINE | Authors: | Suresh, S, Bressi, J.C, Kennedy, K.J, Verlinde, C.L.M.J, Gelb, M.H, Hol, W.G.J. | Deposit date: | 2001-02-12 | Release date: | 2001-10-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors. J.Mol.Biol., 309, 2001
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1HTI
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1IIG
| STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE | Descriptor: | 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J. | Deposit date: | 2001-04-23 | Release date: | 2001-05-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes. Proteins, 10, 1991
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1IIH
| STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHOGLYCERATE | Descriptor: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J. | Deposit date: | 2001-04-23 | Release date: | 2001-05-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes. Proteins, 10, 1991
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1NOL
| OXYGENATED HEMOCYANIN (SUBUNIT TYPE II) | Descriptor: | CALCIUM ION, COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), ... | Authors: | Hazes, B, Hol, W.G.J. | Deposit date: | 1995-10-17 | Release date: | 1996-03-08 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation. Protein Sci., 2, 1993
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