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STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称:	PROTEIN (BARNASE), PROTEIN (BARSTAR)
著者	Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日	1998-12-04
公開日	1998-12-09
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural response to mutation at a protein-protein interface. J.Mol.Biol., 286, 1999

1B3S

STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称:	PROTEIN (BARNASE), PROTEIN (BARSTAR)
著者	Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日	1998-12-01
公開日	1998-12-09
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.39 Å)
主引用文献	Structural response to mutation at a protein-protein interface. J.Mol.Biol., 286, 1999

1B2S

STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称:	PROTEIN (BARNASE), PROTEIN (BARSTAR), SULFATE ION
著者	Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日	1998-11-30
公開日	1998-12-08
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (1.82 Å)
主引用文献	Structural response to mutation at a protein-protein interface. J.Mol.Biol., 286, 1999

1B2U

STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
分子名称:	PROTEIN (BARNASE), PROTEIN (BARSTAR)
著者	Vaughan, C.K, Buckle, A.M, Fersht, A.R.
登録日	1998-12-01
公開日	1998-12-09
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural response to mutation at a protein-protein interface. J.Mol.Biol., 286, 1999

5LAP

p53 cancer mutant Y220C with Cys182 alkylation
分子名称:	5-chloranylpyrimidine-4-carboxylic acid, Cellular tumor antigen p53, ZINC ION
著者	Joerger, A.C, Bauer, M.R, Fersht, A.R.
登録日	2016-06-14
公開日	2016-08-10
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.42 Å)
主引用文献	2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. Proc.Natl.Acad.Sci.USA, 113, 2016

1BAN

THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS
分子名称:	BARNASE
著者	Chen, Y.W, Fersht, A.R, Henrick, K.
登録日	1993-05-19
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants. J.Mol.Biol., 234, 1993

1BAO

THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS
分子名称:	BARNASE, ZINC ION
著者	Chen, Y.W, Fersht, A.R, Henrick, K.
登録日	1993-05-19
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants. J.Mol.Biol., 234, 1993

5NP0

Closed dimer of human ATM (Ataxia telangiectasia mutated)
分子名称:	Serine-protein kinase ATM
著者	Baretic, D, Pollard, H.K, Fisher, D.I, Johnson, C.M, Santhanam, B, Truman, C.M, Kouba, T, Fersht, A.R, Phillips, C, Williams, R.L.
登録日	2017-04-13
公開日	2017-05-17
最終更新日	2019-12-11
実験手法	ELECTRON MICROSCOPY (5.7 Å)
主引用文献	Structures of closed and open conformations of dimeric human ATM. Sci Adv, 3, 2017

1BRS

PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION
分子名称:	BARNASE, BARSTAR
著者	Buckle, A.M, Schreiber, G, Fersht, A.R.
登録日	1994-03-11
公開日	1994-06-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution. Biochemistry, 33, 1994

2J1Y

Human p53 core domain mutant M133L-V203A-N239Y-G245S-N268D
分子名称:	CALCIUM ION, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者	Joerger, A.C, Fersht, A.R.
登録日	2006-08-15
公開日	2006-09-20
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.69 Å)
主引用文献	Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006

2J1X

Human p53 core domain mutant M133L-V203A-Y220C-N239Y-N268D
分子名称:	CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者	Joerger, A.C, Fersht, A.R.
登録日	2006-08-15
公開日	2006-09-20
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006

2J1W

Human p53 core domain mutant M133L-V143A-V203A-N239Y-N268D
分子名称:	CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者	Joerger, A.C, Fersht, A.R.
登録日	2006-08-15
公開日	2006-09-20
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006

2J20

Human p53 core domain mutant M133L-V203A-N239Y-N268D-R273C
分子名称:	CELLULAR TUMOR ANTIGEN P53, SULFATE ION, ZINC ION
著者	Joerger, A.C, Ang, H.C, Fersht, A.R.
登録日	2006-08-15
公開日	2006-09-20
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006

2J1Z

Human p53 core domain mutant M133L-V203A-N239Y-N268D-F270L
分子名称:	CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者	Joerger, A.C, Fersht, A.R.
登録日	2006-08-15
公開日	2006-09-20
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006

2J21

Human p53 core domain mutant M133L-V203A-N239Y-N268D-R282W
分子名称:	CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者	Joerger, A.C, Fersht, A.R.
登録日	2006-08-15
公開日	2006-09-20
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006

1BSE

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BSA

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BSD

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BRG

CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE
分子名称:	BARNASE, ZINC ION
著者	Chen, Y.W, Fersht, A.R, Henrick, K.
登録日	1994-03-30
公開日	1994-06-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Crystallographic analysis of Phe-->Leu substitution in the hydrophobic core of barnase. Acta Crystallogr.,Sect.D, 51, 1995

1BSB

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BSC

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1P7I

CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A
分子名称:	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed
著者	Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F.
登録日	2003-05-02
公開日	2003-10-14
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003

1P7J

Crystal structure of engrailed homeodomain mutant K52E
分子名称:	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed
著者	Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F.
登録日	2003-05-02
公開日	2003-10-14
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003

1QPU

SOLUTION STRUCTURE OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562
分子名称:	CYTOCHROME B562, PROTOPORPHYRIN IX CONTAINING FE
著者	Arnesano, F, Banci, L, Bertini, I, Faraone-Mennella, J, Rosato, A, Barker, P.D, Fersht, A.R.
登録日	1999-05-30
公開日	1999-06-02
最終更新日	2022-03-02
実験手法	SOLUTION NMR
主引用文献	The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry, 38, 1999

1CIQ

COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64
分子名称:	CHYMOTRYPSIN INHIBITOR 2
著者	Buckle, A.M, Fersht, A.R.
登録日	1995-10-02
公開日	1996-03-08
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996

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