6O0M
 
 | | crystal structure of BCL-2 F104L mutation with venetoclax | | 分子名称: | 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-[(3-nitro-4-{[(oxan-4-yl )methyl]amino}phenyl)sulfonyl]-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2, DI(HYDROXYETHYL)ETHER | | 著者 | Birkinshaw, R.W, Luo, C.S, Colman, P.M, Czabotar, P.E. | | 登録日 | 2019-02-16 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.
Nat Commun, 10, 2019
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6O0K
 | | crystal structure of BCL-2 with venetoclax | | 分子名称: | 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-[(3-nitro-4-{[(oxan-4-yl )methyl]amino}phenyl)sulfonyl]-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide, Apoptosis regulator Bcl-2, NONAETHYLENE GLYCOL | | 著者 | Birkinshaw, R.W, Luo, C.S, Colman, P.M, Czabotar, P.E. | | 登録日 | 2019-02-16 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.
Nat Commun, 10, 2019
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6DMZ
 | | Solution structure of ZmD32 | | 分子名称: | Flower-specific gamma-thionin | | 著者 | Harvey, P.J, Craik, D.J. | | 登録日 | 2018-06-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32.
Front Microbiol, 10, 2019
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6B55
 | | Crystal structure of the Plant Defensin NaD1 complexed with phosphatidic acid | | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Flower-specific defensin, ... | | 著者 | Jarva, M, Phan, K, Humble, C, Lay, F.T, Hulett, M, Kvansakul, M. | | 登録日 | 2017-09-28 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
Nat Commun, 9, 2018
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6BL9
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3V8E
 | | Crystal structure of the yeast nicotinamidase Pnc1p bound to the inhibitor nicotinaldehyde | | 分子名称: | MAGNESIUM ION, Nicotinamidase, ZINC ION | | 著者 | Hoadley, K.A, Smith, B.C, Denu, J.M, Keck, J.L. | | 登録日 | 2011-12-22 | | 公開日 | 2012-01-25 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural and Kinetic Isotope Effect Studies of Nicotinamidase (Pnc1) from Saccharomyces cerevisiae.
Biochemistry, 51, 2012
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2LWQ
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2LWS
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2LWU
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2LWV
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2LWT
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4CQK
 | | Crystal structure of ligand-bound NaD1 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, FLOWER-SPECIFIC DEFENSIN, SULFATE ION, ... | | 著者 | Lay, F.T, Mills, G.M, Poon, I.K.H, Baxter, A.A, Hulett, M.D, Kvansakul, M. | | 登録日 | 2014-02-17 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis.
Elife, 3, 2014
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