4FW1
| |
4FVA
| Crystal structure of truncated Caenorhabditis elegans TDP2 | Descriptor: | 1,2-ETHANEDIOL, 5'-tyrosyl-DNA phosphodiesterase, MAGNESIUM ION, ... | Authors: | Shi, K, Kurahashi, K, Aihara, H. | Deposit date: | 2012-06-29 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nat.Struct.Mol.Biol., 19, 2012
|
|
4GEW
| |
4FPV
| Crystal structure of D. rerio TDP2 complexed with single strand DNA product | Descriptor: | DNA (5'-D(P*TP*GP*CP*AP*G)-3'), GLYCEROL, MAGNESIUM ION, ... | Authors: | Shi, K, Kurahashi, K, Aihara, H. | Deposit date: | 2012-06-22 | Release date: | 2012-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nat.Struct.Mol.Biol., 19, 2012
|
|
4FW2
| |
6B0B
| Crystal structure of human APOBEC3H | Descriptor: | APOBEC3H, MCherry, RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Shaban, N.M, Shi, K, Banerjee, S, Harris, R.S, Aihara, H. | Deposit date: | 2017-09-14 | Release date: | 2017-10-25 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (3.2800622 Å) | Cite: | The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Mol. Cell, 69, 2018
|
|
6BBO
| Crystal structure of human APOBEC3H/RNA complex | Descriptor: | APOBEC3H, GLYCEROL, MCherry fluorescent protein, ... | Authors: | Shaban, N.M, Shi, K, Banerjee, S, Harris, R.S, Aihara, H. | Deposit date: | 2017-10-19 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.428 Å) | Cite: | The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Mol. Cell, 69, 2018
|
|
6BUP
| Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with cyanuric acid | Descriptor: | 1,3,5-triazine-2,4,6-triol, 1,3-PROPANDIOL, CALCIUM ION, ... | Authors: | Shi, K, Aihara, H. | Deposit date: | 2017-12-11 | Release date: | 2019-06-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis. Plos One, 14, 2019
|
|
6BUR
| |
6BUN
| |
6BUQ
| |
6CC2
| Crystal Structure of CDC45 from Entamoeba histolytica | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cell division control protein 45 cdc45 putative, ... | Authors: | Shi, K, Kurniawan, F, Kurahashi, K, Bielinsky, A, Aihara, H. | Deposit date: | 2018-02-05 | Release date: | 2018-06-27 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal Structure ofEntamoeba histolyticaCdc45 Suggests a Conformational Switch that May Regulate DNA Replication. iScience, 3, 2018
|
|
6BUO
| |
6BUM
| Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica | Descriptor: | 1,3-PROPANDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Shi, K, Cho, S, Seffernick, J.L, Bera, A, Wackett, L.P, Aihara, H. | Deposit date: | 2017-12-11 | Release date: | 2019-06-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis. Plos One, 14, 2019
|
|
7S6T
| Complex structure of Methane monooxygenase hydroxylase and regulatory subunit H33A | Descriptor: | 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... | Authors: | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | Deposit date: | 2021-09-14 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics. Biochemistry, 61, 2022
|
|
7SPO
| Crystal structure of the SARS-CoV-2 receptor binding domain in complex with VNAR 3B4 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | Authors: | Shi, K, Aihara, H. | Deposit date: | 2021-11-02 | Release date: | 2022-01-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography. Nat Commun, 12, 2021
|
|
7SPP
| |
7S6S
| Complex structure of Methane monooxygenase hydroxylase and regulatory subunit DBL1 | Descriptor: | 1,2-ETHANEDIOL, BENZOIC ACID, FE (III) ION, ... | Authors: | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | Deposit date: | 2021-09-14 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics. Biochemistry, 61, 2022
|
|
7TGR
| Structure of SARS-CoV-2 main protease in complex with GC376 | Descriptor: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 1,2-ETHANEDIOL, ... | Authors: | Esler, M.A, Shi, K, Aihara, H, Harris, R.S. | Deposit date: | 2022-01-09 | Release date: | 2022-05-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells. Mbio, 13, 2022
|
|
7K33
| Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with an abasic lesion at the active site | Descriptor: | DNA (27-MER), Endonuclease Q, MAGNESIUM ION, ... | Authors: | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | Deposit date: | 2020-09-10 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K32
| Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with an abasic lesion at the active site | Descriptor: | DNA (27-MER), Endonuclease Q, MAGNESIUM ION, ... | Authors: | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | Deposit date: | 2020-09-10 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K30
| Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with dU at the active site | Descriptor: | 1,2-ETHANEDIOL, DNA (27-MER), Endonuclease Q, ... | Authors: | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | Deposit date: | 2020-09-10 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K31
| Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with dI at the active site | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (27-MER), ... | Authors: | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | Deposit date: | 2020-09-10 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7KM5
| Crystal structure of SARS-CoV-2 RBD complexed with Nanosota-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Spike protein S1, ... | Authors: | Ye, G, Shi, K, Aihara, H, Li, F. | Deposit date: | 2020-11-02 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | The development of Nanosota - 1 as anti-SARS-CoV-2 nanobody drug candidates. Elife, 10, 2021
|
|
7JN3
| Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048 | Descriptor: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | Authors: | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | Deposit date: | 2020-08-03 | Release date: | 2021-03-17 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Commun Biol, 4, 2021
|
|