8BCS
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![BU of 8bcs by Molmil](/molmil-images/mine/8bcs) | X-ray crystal structure of a de novo designed helix-loop-helix homodimer in an anti arrangement, CC-HP1.0 | Descriptor: | ACETATE ION, CC-HP1.0 | Authors: | Edgell, C.L, Mylemans, B, Naudin, E.A, Smith, A.J, Savery, N.J, Woolfson, D.N. | Deposit date: | 2022-10-17 | Release date: | 2023-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology. Acs Synth Biol, 12, 2023
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8BCT
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![BU of 8bct by Molmil](/molmil-images/mine/8bct) | X-ray crystal structure of a de novo selected helix-loop-helix heterodimer in a syn arrangement, 26alpha/26beta | Descriptor: | 26alpha, 26beta, ACETATE ION, ... | Authors: | Naudin, E.A, Mylemans, B, Smith, A.J, Savery, N.J, Woolfson, D.N. | Deposit date: | 2022-10-17 | Release date: | 2023-06-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology. Acs Synth Biol, 12, 2023
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8W33
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![BU of 8w33 by Molmil](/molmil-images/mine/8w33) | Structure of McrD (methyl-coenzyme M reductase operon protein D) from Methanomassiliicoccus luminyensis | Descriptor: | GLYCEROL, McrD (methyl-coenzyme M reductase operon protein D) | Authors: | Sutherland-Smith, A.J, Carbone, V, Schofield, L.R, Ronimus, R.S. | Deposit date: | 2024-02-21 | Release date: | 2024-07-03 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The crystal structure of methanogen McrD, a methyl-coenzyme M reductase-associated protein. Febs Open Bio, 14, 2024
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4RFL
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![BU of 4rfl by Molmil](/molmil-images/mine/4rfl) | Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii | Descriptor: | 1,2-ETHANEDIOL, Glycerol-1-phosphate dehydrogenase [NAD(P)+], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | Deposit date: | 2014-09-26 | Release date: | 2015-07-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase. J.Biol.Chem., 290, 2015
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4RGQ
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![BU of 4rgq by Molmil](/molmil-images/mine/4rgq) | Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP | Descriptor: | 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, Glycerol-1-phosphate dehydrogenase, ... | Authors: | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | Deposit date: | 2014-09-30 | Release date: | 2015-07-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase. J.Biol.Chem., 290, 2015
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4RGV
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![BU of 4rgv by Molmil](/molmil-images/mine/4rgv) | Crystal structure of the Methanocaldococcus jannaschii G1PDH | Descriptor: | Glycerol-1-phosphate dehydrogenase, MAGNESIUM ION, ZINC ION | Authors: | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | Deposit date: | 2014-09-30 | Release date: | 2015-07-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase. J.Biol.Chem., 290, 2015
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7TZI
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![BU of 7tzi by Molmil](/molmil-images/mine/7tzi) | Structure of a pseudomurein peptide ligase type E from Methanothermobacter thermautotrophicus | Descriptor: | Mur ligase family protein | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | Deposit date: | 2022-02-15 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.911 Å) | Cite: | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases. Microbiology (Reading, Engl.), 168, 2022
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7UFP
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![BU of 7ufp by Molmil](/molmil-images/mine/7ufp) | Structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | Descriptor: | Mur ligase middle domain protein, SULFATE ION, URIDINE-5'-DIPHOSPHATE | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | Deposit date: | 2022-03-23 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases. Microbiology (Reading, Engl.), 168, 2022
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3UUM
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![BU of 3uum by Molmil](/molmil-images/mine/3uum) | |
3UUN
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![BU of 3uun by Molmil](/molmil-images/mine/3uun) | |
3UUL
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![BU of 3uul by Molmil](/molmil-images/mine/3uul) | |
1A9W
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![BU of 1a9w by Molmil](/molmil-images/mine/1a9w) | HUMAN EMBRYONIC GOWER II CARBONMONOXY HEMOGLOBIN | Descriptor: | CARBON MONOXIDE, HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), ... | Authors: | Sutherland-Smith, A.J, Baker, H.M, Hofmann, O.M, Brittain, T, Baker, E.N. | Deposit date: | 1998-04-11 | Release date: | 1998-06-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of gower II (alpha2 epsilon2) haemoglobin at 2.9 A resolution. J.Mol.Biol., 280, 1998
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6VR7
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![BU of 6vr7 by Molmil](/molmil-images/mine/6vr7) | Structure of a pseudomurein peptide ligase type C from Methanothermus fervidus | Descriptor: | ACETOACETIC ACID, GLYCEROL, Mur ligase middle domain protein, ... | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | Deposit date: | 2020-02-06 | Release date: | 2021-02-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry FEMS Microbes, 2, 2021
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6VR8
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![BU of 6vr8 by Molmil](/molmil-images/mine/6vr8) | Structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Mur ligase middle domain protein, ... | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | Deposit date: | 2020-02-06 | Release date: | 2021-08-11 | Last modified: | 2023-02-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases. Microbiology (Reading, Engl.), 168, 2022
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5CK7
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![BU of 5ck7 by Molmil](/molmil-images/mine/5ck7) | |
5CCF
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![BU of 5ccf by Molmil](/molmil-images/mine/5ccf) | |
7JT8
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![BU of 7jt8 by Molmil](/molmil-images/mine/7jt8) | Apo structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | Descriptor: | MAGNESIUM ION, Mur ligase middle domain protein, SULFATE ION | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | Deposit date: | 2020-08-17 | Release date: | 2021-09-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases. Microbiology (Reading, Engl.), 168, 2022
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4GMH
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![BU of 4gmh by Molmil](/molmil-images/mine/4gmh) | Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase | Descriptor: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ACETATE ION | Authors: | Brown, R.L, Anderson, B.F, Norris, G.E, Tyler, P.C, Evans, G.B, Sutherland-Smith, A.J. | Deposit date: | 2012-08-15 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase To be Published
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4FIO
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![BU of 4fio by Molmil](/molmil-images/mine/4fio) | Crystal Structure of Methenyltetrahydromethanopterin Cyclohydrolase from Methanobrevibacter ruminantium | Descriptor: | ETHYL ACETATE, ISOPROPYL ALCOHOL, Methenyltetrahydromethanopterin cyclohydrolase | Authors: | Carbone, V, Schofield, L.R, Beattie, A.K, Sutherland-Smith, A.J, Ronimus, R.S. | Deposit date: | 2012-06-10 | Release date: | 2013-07-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | The crystal structure of methenyltetrahydromethanopterin cyclohydrolase from Methanobrevibacter ruminantium. Proteins, 81, 2013
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6DNT
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![BU of 6dnt by Molmil](/molmil-images/mine/6dnt) | UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with UDP-N-acetylmuramic acid | Descriptor: | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, NAD-dependent epimerase/dehydratase, ... | Authors: | Carbone, V, Schofield, L.R, Sang, C, Sutherland-Smith, A.J, Ronimus, R.S. | Deposit date: | 2018-06-07 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid. Proteins, 86, 2018
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6P8C
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![BU of 6p8c by Molmil](/molmil-images/mine/6p8c) | 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus | Descriptor: | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, CHLORIDE ION, GLYCEROL, ... | Authors: | Carbone, V, Schofield, L.R, Hannus, I, Sutherland-Smith, A.J, Ronimus, R.S. | Deposit date: | 2019-06-06 | Release date: | 2020-06-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | The Crystal Structure of 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus To Be Published
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6PNL
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![BU of 6pnl by Molmil](/molmil-images/mine/6pnl) | Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus | Descriptor: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S. | Deposit date: | 2019-07-02 | Release date: | 2020-07-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus To Be Published
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6PMH
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![BU of 6pmh by Molmil](/molmil-images/mine/6pmh) | Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S. | Deposit date: | 2019-07-01 | Release date: | 2020-07-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus To Be Published
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1DXX
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![BU of 1dxx by Molmil](/molmil-images/mine/1dxx) | |
3HOP
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![BU of 3hop by Molmil](/molmil-images/mine/3hop) | Structure of the actin-binding domain of human filamin A | Descriptor: | Filamin-A, PHOSPHATE ION | Authors: | Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. | Deposit date: | 2009-06-03 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders Hum.Mol.Genet., 18, 2009
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