7MP8
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7MP9
| Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 phosphorylated at Ser205 in complex with ADP analog | Descriptor: | AMP PHOSPHORAMIDATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Rasool, S, Veyron, S, Trempe, J.F. | Deposit date: | 2021-05-04 | Release date: | 2021-12-01 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Mol.Cell, 82, 2022
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8UDC
| Crystal structure of TcPINK1 in complex with CYC116 | Descriptor: | (4P)-4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | Authors: | Veyron, S, Rasool, S, Trempe, J.F. | Deposit date: | 2023-09-28 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Characterization of a small-molecule inhibitor of PINK1, a precursor tool compound for the study of Parkinson's disease To Be Published
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8UCT
| Crystal structure of TcPINK1 in complex with PRT | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide, SULFATE ION, ... | Authors: | Veyron, S, Rasool, S, Trempe, J.F. | Deposit date: | 2023-09-27 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Characterization of a new family of PINK1 inhibitors To Be Published
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4ZYN
| Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130) | Descriptor: | E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION | Authors: | Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K. | Deposit date: | 2015-05-21 | Release date: | 2015-08-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | A Ubl/ubiquitin switch in the activation of Parkin. Embo J., 34, 2015
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