2YXF
 
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2D4D
 | | The Crystal Structure of human beta2-microglobulin, L39W W60F W95F Mutant | | Descriptor: | Beta-2-microglobulin, SODIUM ION | | Authors: | Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. | | Deposit date: | 2005-10-17 | | Release date: | 2006-08-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
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2D4F
 | | The Crystal Structure of human beta2-microglobulin | | Descriptor: | Beta-2-microglobulin, SODIUM ION | | Authors: | Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. | | Deposit date: | 2005-10-18 | | Release date: | 2006-08-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
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1VCK
 | | Crystal structure of ferredoxin component of carbazole 1,9a-dioxygenase of Pseudomonas resinovorans strain CA10 | | Descriptor: | FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, HYDROSULFURIC ACID, ... | | Authors: | Nam, J.-W, Noguchi, H, Fujiomoto, Z, Mizuno, H, Fushinobu, S, Kobashi, N, Iwata, K, Yoshida, T, Habe, H, Yamane, H, Omori, T, Nojiri, H. | | Deposit date: | 2004-03-09 | | Release date: | 2005-03-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the ferredoxin component of carbazole 1,9a-dioxygenase of Pseudomonas resinovorans strain CA10, a novel Rieske non-heme iron oxygenase system
PROTEINS, 58, 2005
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1IU9
 | | Crystal structure of the C-terminal domain of aspartate racemase from Pyrococcus horikoshii OT3 | | Descriptor: | CALCIUM ION, aspartate racemase | | Authors: | Liu, L, Iwata, K, Yohda, M, Miki, K. | | Deposit date: | 2002-02-28 | | Release date: | 2003-09-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural insight into gene duplication, gene fusion and domain swapping in the evolution of PLP-independent amino acid racemases
FEBS LETT., 528, 2002
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1JFL
 | | CRYSTAL STRUCTURE DETERMINATION OF ASPARTATE RACEMASE FROM AN ARCHAEA | | Descriptor: | ASPARTATE RACEMASE | | Authors: | Liu, L.J, Iwata, K, Kita, A, Kawarabayasi, Y, Yohda, M, Miki, K. | | Deposit date: | 2001-06-21 | | Release date: | 2002-06-05 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization.
J.Mol.Biol., 319, 2002
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1HZ3
 | | ALZHEIMER'S DISEASE AMYLOID-BETA PEPTIDE (RESIDUES 10-35) | | Descriptor: | A-BETA AMYLOID | | Authors: | Zhang, S, Iwata, K, Lachenmann, M.J, Peng, J.W, Li, S, Stimson, E.R, Lu, Y, Felix, A.M, Maggio, J.E, Lee, J.P. | | Deposit date: | 2001-01-23 | | Release date: | 2001-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The Alzheimer's peptide a beta adopts a collapsed coil structure in water.
J.Struct.Biol., 130, 2000
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2E8D
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8Z8V
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8Z8M
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6P5P
 | | Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Anti-Tumor Agent | | Descriptor: | 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one, Rho-associated protein kinase 2 | | Authors: | Hoffman, I.D, Skene, R.J. | | Deposit date: | 2019-05-30 | | Release date: | 2020-01-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent.
J.Med.Chem., 63, 2020
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6P5M
 | | Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Anti-Tumor Agent | | Descriptor: | 6-(5-methyl-1H-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3H)-one, Rho-associated protein kinase 2 | | Authors: | Hoffman, I.D, Skene, R.J. | | Deposit date: | 2019-05-30 | | Release date: | 2020-01-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent.
J.Med.Chem., 63, 2020
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1J1I
 | | Crystal structure of a His-tagged Serine Hydrolase Involved in the Carbazole Degradation (CarC enzyme) | | Descriptor: | meta cleavage compound hydrolase | | Authors: | Habe, H, Morii, K, Fushinobu, S, Nam, J.W, Ayabe, Y, Yoshida, T, Wakagi, T, Yamane, H, Nojiri, H, Omori, T. | | Deposit date: | 2002-12-05 | | Release date: | 2003-06-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal structure of a histidine-tagged serine hydrolase involved in the carbazole degradation (CarC enzyme).
Biochem.Biophys.Res.Commun., 303, 2003
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