2IX1
 
 | | RNase II D209N mutant | | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP *AP*AP*A)-3', EXORIBONUCLEASE 2, MAGNESIUM ION | | Authors: | Frazao, C, McVey, C.E, Amblar, M, Barbas, A, Vonrhein, C, Arraiano, C.M, Carrondo, M.A. | | Deposit date: | 2006-07-05 | | Release date: | 2006-10-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Unravelling the Dynamics of RNA Degradation by Ribonuclease II and its RNA-Bound Complex
Nature, 443, 2006
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2IX0
 | | RNase II | | Descriptor: | CALCIUM ION, CYTIDINE-5'-MONOPHOSPHATE, EXORIBONUCLEASE 2, ... | | Authors: | Frazao, C, Mcvey, C.E, Amblar, M, Barbas, A, Vonrhein, C, Arraiano, C.M, Carrondo, M.A. | | Deposit date: | 2006-07-05 | | Release date: | 2006-10-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Unravelling the Dynamics of RNA Degradation by Ribonuclease II and its RNA-Bound Complex
Nature, 7, 2006
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9FZG
 | | Crystal structure of the hPXR-LBD in complex with compound JMV7035 | | Descriptor: | 2-(1-adamantyl)-~{N}-[2-[2-[2-oxidanylidene-2-[7-[1-(phenylmethyl)-5-[(2,4,6-trimethylphenyl)sulfonylamino]benzimidazol-2-yl]heptylamino]ethoxy]ethoxy]ethyl]ethanamide, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Delfosse, V, Bourguet, W. | | Deposit date: | 2024-07-05 | | Release date: | 2025-02-19 | | Last modified: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A two-in-one expression construct for biophysical and structural studies of the human pregnane X receptor ligand-binding domain, a pharmaceutical and environmental target.
Acta Crystallogr.,Sect.F, 81, 2025
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9FZH
 | | Crystal structure of the hPXR-LBD in complex with compound JMV6995 | | Descriptor: | 2-(1-adamantyl)-~{N}-[7-[1-(phenylmethyl)-5-[(2,4,6-trimethylphenyl)sulfonylamino]benzimidazol-2-yl]heptyl]ethanamide, Nuclear receptor subfamily 1 group I member 2 | | Authors: | Delfosse, V, Bourguet, W. | | Deposit date: | 2024-07-05 | | Release date: | 2025-02-19 | | Last modified: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A two-in-one expression construct for biophysical and structural studies of the human pregnane X receptor ligand-binding domain, a pharmaceutical and environmental target.
Acta Crystallogr.,Sect.F, 81, 2025
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9FZI
 | | A new crystal structure of the hPXR-LBD in fusion with an SRC1 co-activator peptide and in complex with SR12813 (P212121 form) | | Descriptor: | Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1, [2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER | | Authors: | Carivenc, C, Blanc, P, Bourguet, W, Delfosse, V. | | Deposit date: | 2024-07-05 | | Release date: | 2025-02-19 | | Last modified: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A two-in-one expression construct for biophysical and structural studies of the human pregnane X receptor ligand-binding domain, a pharmaceutical and environmental target.
Acta Crystallogr.,Sect.F, 81, 2025
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9FZJ
 | | A new crystal structure of the hPXR-LBD in complex with SR12813 (P43212 form) | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Carivenc, C, Blanc, P, Bourguet, W, Delfosse, V. | | Deposit date: | 2024-07-05 | | Release date: | 2025-02-19 | | Last modified: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A two-in-one expression construct for biophysical and structural studies of the human pregnane X receptor ligand-binding domain, a pharmaceutical and environmental target.
Acta Crystallogr.,Sect.F, 81, 2025
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