4JEU
| Crystal Structure of Munc18a and Syntaxin1 with native N-terminus complex | Descriptor: | Syntaxin-1A, Syntaxin-binding protein 1 | Authors: | Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I. | Deposit date: | 2013-02-27 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KRR
| Crystal structure of Drosophila WntD N-terminal domain-linker (residues 31-240) | Descriptor: | GLYCEROL, SODIUM ION, Wnt inhibitor of Dorsal protein | Authors: | Chu, M.L.-H, Choi, H.-J, Ahn, V.E, Daniels, D.L, Nusse, R, Weis, W.I. | Deposit date: | 2013-05-16 | Release date: | 2013-07-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.124 Å) | Cite: | Structural Studies of Wnts and Identification of an LRP6 Binding Site. Structure, 21, 2013
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4JEH
| Crystal Structure of Munc18a and Syntaxin1 lacking N-peptide complex | Descriptor: | Syntaxin-1A, Syntaxin-binding protein 1 | Authors: | Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I. | Deposit date: | 2013-02-27 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation. Proc.Natl.Acad.Sci.USA, 110, 2013
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1BCH
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4JQI
| Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide | Descriptor: | 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ... | Authors: | Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J. | Deposit date: | 2013-03-20 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature, 497, 2013
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4KZW
| Structure of the carbohydrate-recognition domain of the C-type lectin mincle | Descriptor: | C-TYPE LECTIN MINCLE, CALCIUM ION, CITRATE ANION, ... | Authors: | Feinberg, H, Jegouzo, S.A.F, Rowntree, T.J.W, Guan, Y, Brash, M.A, Taylor, M.E, Weis, W.I, Drickamer, K. | Deposit date: | 2013-05-30 | Release date: | 2013-08-28 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle. J.Biol.Chem., 288, 2013
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1AFB
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1BCJ
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4MQS
| Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo | Descriptor: | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Muscarinic acetylcholine receptor M2, Nanobody 9-8 | Authors: | Kruse, A.C, Ring, A.M, Manglik, A, Hu, J, Hu, K, Eitel, K, Huebner, H, Pardon, E, Valant, C, Sexton, P.M, Christopoulos, A, Felder, C.C, Gmeiner, P, Steyaert, J, Weis, W.I, Garcia, K.C, Wess, J, Kobilka, B.K. | Deposit date: | 2013-09-16 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature, 504, 2013
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4N34
| Structure of langerin CRD I313 with alpha-MeGlcNAc | Descriptor: | C-type lectin domain family 4 member K, CALCIUM ION, methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside | Authors: | Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E. | Deposit date: | 2013-10-06 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Common polymorphisms in human langerin change specificity for glycan ligands. J.Biol.Chem., 288, 2013
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1KMB
| SELECTIN-LIKE MUTANT OF MANNOSE-BINDING PROTEIN A | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-A | Authors: | Ng, K.K.-S, Weis, W.I. | Deposit date: | 1996-11-07 | Release date: | 1997-02-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a selectin-like mutant of mannose-binding protein complexed with sialylated and sulfated Lewis(x) oligosaccharides. Biochemistry, 36, 1997
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1D2N
| D2 DOMAIN OF N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN | Descriptor: | GLYCEROL, MAGNESIUM ION, N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN, ... | Authors: | Lenzen, C.U, Steinmann, D, Whiteheart, S.W, Weis, W.I. | Deposit date: | 1998-06-30 | Release date: | 1998-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein. Cell(Cambridge,Mass.), 94, 1998
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1DK8
| CRYSTAL STRUCTURE OF THE RGS-HOMOLOGOUS DOMAIN OF AXIN | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AXIN, GLYCEROL, ... | Authors: | Spink, K.E, Polakis, P, Weis, W.I. | Deposit date: | 1999-12-06 | Release date: | 2000-07-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural basis of the Axin-adenomatous polyposis coli interaction. EMBO J., 19, 2000
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1DOW
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1BUU
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1DOV
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1EGI
| STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR | Descriptor: | CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR | Authors: | Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I. | Deposit date: | 2000-02-15 | Release date: | 2000-08-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor. J.Biol.Chem., 275, 2000
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1EMU
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1BV4
| APO-MANNOSE-BINDING PROTEIN-C | Descriptor: | PROTEIN (MANNOSE-BINDING PROTEIN-C) | Authors: | Ng, K.K.-S, Weis, W.I. | Deposit date: | 1998-09-22 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Ca2+-dependent structural changes in C-type mannose-binding proteins. Biochemistry, 37, 1998
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1EGG
| STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR | Descriptor: | CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR | Authors: | Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I. | Deposit date: | 2000-02-15 | Release date: | 2000-08-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor. J.Biol.Chem., 275, 2000
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1IFQ
| Sec22b N-terminal domain | Descriptor: | GLYCEROL, vesicle trafficking protein Sec22b | Authors: | Gonzalez Jr, L.C, Weis, W.I, Scheller, R.H. | Deposit date: | 2001-04-13 | Release date: | 2001-05-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel snare N-terminal domain revealed by the crystal structure of Sec22b. J.Biol.Chem., 276, 2001
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1JTH
| Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a | Descriptor: | SNAP25, syntaxin 1a | Authors: | Misura, K.M.S, Gonzalez Jr, L.C, May, A.P, Scheller, R.H, Weis, W.I. | Deposit date: | 2001-08-21 | Release date: | 2001-11-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a. J.Biol.Chem., 276, 2001
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1K9J
| Complex of DC-SIGNR and GlcNAc2Man3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, mDC-SIGN2 TYPE I ISOFORM | Authors: | Feinberg, H, Mitchell, D.A, Drickamer, K, Weis, W.I. | Deposit date: | 2001-10-29 | Release date: | 2001-12-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR. Science, 294, 2001
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1K9I
| Complex of DC-SIGN and GlcNAc2Man3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, mDC-SIGN1B type I isoform | Authors: | Feinberg, H, Mitchell, D.A, Drickamer, K, Weis, W.I. | Deposit date: | 2001-10-29 | Release date: | 2001-12-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR. Science, 294, 2001
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1KWU
| Rat mannose binding protein A complexed with a-Me-Man | Descriptor: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ... | Authors: | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | Deposit date: | 2002-01-30 | Release date: | 2002-07-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
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