2NRT
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2NRV
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5OKI
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![BU of 5oki by Molmil](/molmil-images/mine/5oki) | |
5OKC
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4ALI
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![BU of 4ali by Molmil](/molmil-images/mine/4ali) | Crystal structure of S. aureus FabI in complex with NADP and triclosan (P1) | Descriptor: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | Deposit date: | 2012-03-04 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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4ALK
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![BU of 4alk by Molmil](/molmil-images/mine/4alk) | Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol | Descriptor: | 5-ETHYL-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | Authors: | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | Deposit date: | 2012-03-04 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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4A15
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![BU of 4a15 by Molmil](/molmil-images/mine/4a15) | Crystal structure of an XPD DNA complex | Descriptor: | 5'-D(*DTP*AP*CP*GP)-3', ATP-DEPENDENT DNA HELICASE TA0057, CALCIUM ION, ... | Authors: | Kuper, J, Wolski, S.C, Michels, G, Kisker, C. | Deposit date: | 2011-09-14 | Release date: | 2012-02-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional and Structural Studies of the Nucleotide Excision Repair Helicase Xpd Suggest a Polarity for DNA Translocation. Embo J., 31, 2011
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4ALN
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![BU of 4aln by Molmil](/molmil-images/mine/4aln) | Crystal structure of S. aureus FabI (P32) | Descriptor: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] | Authors: | Schiebel, J, Kisker, C. | Deposit date: | 2012-03-04 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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4ALJ
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![BU of 4alj by Molmil](/molmil-images/mine/4alj) | Crystal structure of S. aureus FabI in complex with NADP and 5-chloro- 2-phenoxyphenol | Descriptor: | 5-CHLORO-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | Authors: | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | Deposit date: | 2012-03-04 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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4ALL
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![BU of 4all by Molmil](/molmil-images/mine/4all) | Crystal structure of S. aureus FabI in complex with NADP and triclosan (P212121) | Descriptor: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRICLOSAN | Authors: | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | Deposit date: | 2012-03-04 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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4ALM
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![BU of 4alm by Molmil](/molmil-images/mine/4alm) | Crystal structure of S. aureus FabI (P43212) | Descriptor: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], SULFATE ION | Authors: | Schiebel, J, Kisker, C. | Deposit date: | 2012-03-04 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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7AD8
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![BU of 7ad8 by Molmil](/molmil-images/mine/7ad8) | Core TFIIH-XPA-DNA complex with modelled p62 subunit | Descriptor: | DNA (49-MER), DNA repair protein complementing XP-A cells, General transcription and DNA repair factor IIH helicase subunit XPB, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2020-09-14 | Release date: | 2021-07-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair. Nucleic Acids Res., 48, 2020
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6EXO
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![BU of 6exo by Molmil](/molmil-images/mine/6exo) | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | Descriptor: | (3~{S},14~{E})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease | Authors: | Dietzel, U, Kisker, C. | Deposit date: | 2017-11-08 | Release date: | 2018-04-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
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6EX8
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![BU of 6ex8 by Molmil](/molmil-images/mine/6ex8) | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | Descriptor: | (3~{S})-~{N}-[1-(aminomethyl)cyclopropyl]-19-chloranyl-5-oxidanylidene-9-(trifluoromethyl)-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease | Authors: | Dietzel, U, Kisker, C. | Deposit date: | 2017-11-07 | Release date: | 2018-04-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
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6EXQ
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![BU of 6exq by Molmil](/molmil-images/mine/6exq) | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | Descriptor: | (3~{S})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-8-methoxy-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease | Authors: | Dietzel, U, Kisker, C. | Deposit date: | 2017-11-08 | Release date: | 2018-04-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
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7BMS
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![BU of 7bms by Molmil](/molmil-images/mine/7bms) | HEWL in cesium chloride (1.5 M CsCl in crystallization condition and cryo protectant) | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMW
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![BU of 7bmw by Molmil](/molmil-images/mine/7bmw) | p62PH in cesium chloride (0.75 M CsCl in cryo protectant) | Descriptor: | CESIUM ION, CHLORIDE ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMO
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![BU of 7bmo by Molmil](/molmil-images/mine/7bmo) | HEWL in cesium chloride (0.25 M CsCl in protein buffer) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Hen egg white lysozyme, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMP
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![BU of 7bmp by Molmil](/molmil-images/mine/7bmp) | HEWL in cesium chloride (0.25 M CsCl in protein buffer and cryo protectant). | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMU
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![BU of 7bmu by Molmil](/molmil-images/mine/7bmu) | p62PH in cesium chloride (0.25 M CsCl in protein buffer) | Descriptor: | CESIUM ION, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMX
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7BMZ
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![BU of 7bmz by Molmil](/molmil-images/mine/7bmz) | p62PH in potassium chloride | Descriptor: | CHLORIDE ION, POTASSIUM ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMV
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7BMR
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![BU of 7bmr by Molmil](/molmil-images/mine/7bmr) | HEWL in cesium chloride (0.25 M CsCl in protein buffer and 1.71 M CsCl in cryo protectant) | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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7BMQ
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![BU of 7bmq by Molmil](/molmil-images/mine/7bmq) | HEWL in cesium chloride (1.71 M CsCl in cryo protectant) | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
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