5YIJ
 
 | | Structure of a Legionella effector with substrates | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SdeA, Ubiquitin | | Authors: | Feng, Y, Mu, Y, Wang, H. | | Deposit date: | 2017-10-05 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
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5HWG
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5X04
 | | 12:0-ACP thioesterase from Umbellularia californica | | Descriptor: | Dodecanoyl-[acyl-carrier-protein] hydrolase, chloroplastic | | Authors: | Xue, S, Feng, Y. | | Deposit date: | 2017-01-19 | | Release date: | 2017-10-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structural Insight into Acyl-ACP Thioesterase toward Substrate Specificity Design.
ACS Chem. Biol., 12, 2017
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6A9Y
 | | The crystal structure of Mu homology domain of SGIP1 | | Descriptor: | SH3-containing GRB2-like protein 3-interacting protein 1 | | Authors: | Feng, Y, Liu, X. | | Deposit date: | 2018-07-16 | | Release date: | 2018-09-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | SGIP1 dimerizes via intermolecular disulfide bond in mu HD domain during cellular endocytosis.
Biochem. Biophys. Res. Commun., 505, 2018
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9IK2
 | | The co-crystal structure of SARS-CoV-2 Mpro in complex with compound H109 | | Descriptor: | 3C-like proteinase, tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S)-1-azanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-3,3-dimethyl-1-oxidanylidene-butan-2-yl]carbamate | | Authors: | Feng, Y, Zheng, W.Y, Han, P, Fu, L.F, Qi, J.X. | | Deposit date: | 2024-06-26 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure-guided discovery of a small molecule inhibitor of SARS-CoV-2 main protease with potent in vitro and in vivo antiviral activities
To Be Published
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1APC
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5HWH
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5X38
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5X35
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5X36
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5X37
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5X3C
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4MEY
 | | Crystal structure of Escherichia coli RNA polymerase holoenzyme | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | | Deposit date: | 2013-08-27 | | Release date: | 2014-05-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.948 Å) | | Cite: | Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
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4MEX
 | | Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | | Deposit date: | 2013-08-27 | | Release date: | 2014-05-21 | | Last modified: | 2014-06-25 | | Method: | X-RAY DIFFRACTION (3.902 Å) | | Cite: | Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
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5XVM
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5X39
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5X34
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6INW
 | | A Pericyclic Reaction enzyme | | Descriptor: | O-methyltransferase lepI, S-ADENOSYLMETHIONINE | | Authors: | Feng, Y, Chang, M, Wang, H, Liu, Z, Zhou, Y. | | Deposit date: | 2018-10-28 | | Release date: | 2019-07-03 | | Method: | X-RAY DIFFRACTION (1.798 Å) | | Cite: | Crystal structure of the multifunctional SAM-dependent enzyme LepI provides insights into its catalytic mechanism.
Biochem.Biophys.Res.Commun., 515, 2019
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6KG9
 | | Solution structure of CaDoc0917 from Clostridium acetobutylicum | | Descriptor: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGF
 | | Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 8.2 | | Descriptor: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGC
 | | Crystal structure of CaDoc0917(R49D)-CaCohA2 complex at pH 5.4 | | Descriptor: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGD
 | | Crystal structure of CaDoc0917(R49D)-CaCohA2 complex at pH 8.0 | | Descriptor: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGE
 | | Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 5.5 | | Descriptor: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KG8
 | | Solution structure of CaCohA2 from Clostridium acetobutylicum | | Descriptor: | Probably cellulosomal scaffolding protein, secreted cellulose-binding and cohesin domain | | Authors: | Feng, Y, Yao, X. | | Deposit date: | 2019-07-11 | | Release date: | 2020-07-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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4JND
 | | Structure of a C.elegans sex determining protein | | Descriptor: | Ca(2+)/calmodulin-dependent protein kinase phosphatase, MAGNESIUM ION | | Authors: | Feng, Y, Zhang, Y, Ge, J, Yang, M. | | Deposit date: | 2013-03-15 | | Release date: | 2013-06-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.652 Å) | | Cite: | Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.
J.Biol.Chem., 288, 2013
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