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4I6B
Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein Phosphorylation in Rat Brain
Descriptor:
(7R)-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one, Serine/threonine-protein kinase PLK2
Authors:
Pan, H.
Deposit date:
2012-11-29
Release date:
2013-11-20
Last modified:
2024-02-28
Method:
X-RAY DIFFRACTION (1.8 Å)
Cite:
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce alpha-synuclein phosphorylation in rat brain.
Chemmedchem, 8, 2013
4I6F
Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein Phosphorylation in Rat Brain
Descriptor:
(7R)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one, Serine/threonine-protein kinase PLK2
Authors:
Pan, H.
Deposit date:
2012-11-29
Release date:
2013-11-20
Last modified:
2024-02-28
Method:
X-RAY DIFFRACTION (2.9 Å)
Cite:
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce alpha-synuclein phosphorylation in rat brain.
Chemmedchem, 8, 2013
5V8R
Small Molecule Inhibitor ABS-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Descriptor:
Botulinum neurotoxin type A, N-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]-2-sulfanylacetamide, ZINC ION
Authors:
Allen, K.N
,
Silvaggi, N.R.
Deposit date:
2017-03-22
Release date:
2017-07-26
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (1.9 Å)
Cite:
Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Toxicon, 137, 2017
5V8U
Small Molecule Inhibitor ABS-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Descriptor:
Botulinum neurotoxin type A, N-[3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]-2-sulfanylacetamide, ZINC ION
Authors:
Allen, K.N
,
Silvaggi, N.R.
Deposit date:
2017-03-22
Release date:
2017-07-26
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (2.05 Å)
Cite:
Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Toxicon, 137, 2017
5V8P
Small Molecule Inhibitor ABS-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Descriptor:
Botulinum neurotoxin type A, N-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-2-sulfanylacetamide, ZINC ION
Authors:
Allen, K.N
,
Silvaggi, N.R.
Deposit date:
2017-03-22
Release date:
2017-07-26
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (2.501 Å)
Cite:
Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Toxicon, 137, 2017
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221051
數據於2024-06-12公開中