6SJ0
 
 | | Amidohydrolase, AHS | | Descriptor: | Amidohydrolase, BICARBONATE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6SSF
 | | Transaminase with LCS bound | | Descriptor: | ForI-LCS, SULFATE ION, [4-[(~{Z})-[(2~{S},5~{S})-5-(azanyloxymethyl)-3,6-bis(oxidanylidene)piperazin-2-yl]methoxyiminomethyl]-6-methyl-5-oxidanyl-pyridin-3-yl]methyl dihydrogen phosphate | | Authors: | Naismith, J.H, Gao, S. | | Deposit date: | 2019-09-06 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis.
Chem.Commun.(Camb.), 55, 2019
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6SIX
 | | PaaK family AMP-ligase with ANP | | Descriptor: | 1,2-ETHANEDIOL, AMP-dependent synthetase and ligase, CITRATE ANION, ... | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6SSD
 | | Transaminase with PLP bound | | Descriptor: | ForI-PLP, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | Authors: | Naismith, J.H, Gao, S. | | Deposit date: | 2019-09-06 | | Release date: | 2020-01-15 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis.
Chem.Commun.(Camb.), 55, 2019
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6SSE
 | | Transaminase with PMP bound | | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ForI-PMP, SULFATE ION | | Authors: | Naismith, J.H, Gao, S. | | Deposit date: | 2019-09-06 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis.
Chem.Commun.(Camb.), 55, 2019
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6SIZ
 | | PaaK family AMP-ligase with ANP and substrate | | Descriptor: | 1,2-ETHANEDIOL, 3-HYDROXYANTHRANILIC ACID, AMP-dependent synthetase and ligase, ... | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6SJ3
 | | Amidohydrolase, AHS with 3-HBA | | Descriptor: | 1,2-ETHANEDIOL, 3-HYDROXYBENZOIC ACID, Amidohydrolase, ... | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.17 Å) | | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6SIY
 | | PaaK family AMP-ligase with AMP and substrate | | Descriptor: | 1,2-ETHANEDIOL, 3-HYDROXYANTHRANILIC ACID, ADENOSINE MONOPHOSPHATE, ... | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6TM4
 | | NatL2 in complex with two molecules of salicylic acid | | Descriptor: | 2-HYDROXYBENZOIC ACID, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2019-12-03 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Angew.Chem.Int.Ed.Engl., 59, 2020
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1QGL
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7BK9
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7BIS
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5N0O
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5N0Q
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5N0P
 | | Crystal structure of OphA-DeltaC18 in complex with SAH | | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, peptide N-methyltranferase | | Authors: | Naismith, J.H, Song, H. | | Deposit date: | 2017-02-03 | | Release date: | 2018-02-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds.
Sci Adv, 4, 2018
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1DZT
 | | RMLC FROM SALMONELLA TYPHIMURIUM | | Descriptor: | 3'-O-ACETYLTHYMIDINE-(5' DIPHOSPHATE PHENYL ESTER), 3'-O-ACETYLTHYMIDINE-5'-DIPHOSPHATE, DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, ... | | Authors: | Naismith, J.H, Giraud, M.F. | | Deposit date: | 2000-03-07 | | Release date: | 2000-04-18 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Rmlc, the Third Enzyme of Dtdp-L-Rhamnose Pathway, is a New Class of Epimerase.
Nat.Struct.Biol., 7, 2000
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1DZR
 | | RmlC from Salmonella typhimurium | | Descriptor: | DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, GLYCEROL, SULFATE ION | | Authors: | Naismith, J.H, Giraud, M.F. | | Deposit date: | 2000-03-07 | | Release date: | 2000-04-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Rmlc, the Third Enzyme of Dtdp-L-Rhamnose Pathway, is a New Class of Epimerase.
Nat.Struct.Biol., 7, 2000
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5H8C
 | | Truncated XPD | | Descriptor: | IRON/SULFUR CLUSTER, XPD/Rad3 related DNA helicase | | Authors: | Naismith, J.H, Constantinescu, D. | | Deposit date: | 2015-12-23 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Mechanism of DNA loading by the DNA repair helicase XPD.
Nucleic Acids Res., 44, 2016
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5H8W
 | | XPD mechanism | | Descriptor: | ATP-dependent DNA helicase Ta0057, DNA (5'-D(P*TP*AP*CP*GP*A)-3'), IRON/SULFUR CLUSTER, ... | | Authors: | Naismith, J.H, Constantinescu, D. | | Deposit date: | 2015-12-24 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism of DNA loading by the DNA repair helicase XPD.
Nucleic Acids Res., 44, 2016
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2V81
 | | Native KDPGal structure | | Descriptor: | 2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE | | Authors: | Naismith, J.H. | | Deposit date: | 2007-08-02 | | Release date: | 2007-08-14 | | Last modified: | 2018-03-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Characterization and crystal structure of Escherichia coli KDPGal aldolase.
Bioorg. Med. Chem., 16, 2008
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2VG3
 | | Rv2361 with citronellyl pyrophosphate | | Descriptor: | CHLORIDE ION, GERANYL DIPHOSPHATE, GLYCEROL, ... | | Authors: | Naismith, J.H, Wang, W, Dong, C. | | Deposit date: | 2007-11-08 | | Release date: | 2008-05-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2VG2
 | | Rv2361 with IPP | | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, DIPHOSPHATE, ... | | Authors: | Naismith, J.H, Wang, W, Dong, C. | | Deposit date: | 2007-11-07 | | Release date: | 2007-11-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2V7K
 | | PrnB D-tryptophan complex | | Descriptor: | D-TRYPTOPHAN, PRNB, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Naismith, J.H. | | Deposit date: | 2007-07-30 | | Release date: | 2007-08-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway is Related to the Heme-Dependent Dioxygenase Superfamily
Biochemistry, 46, 2007
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2VG1
 | | Rv1086 E,E-farnesyl diphosphate complex | | Descriptor: | FARNESYL DIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Naismith, J.H, Wang, W, Dong, C. | | Deposit date: | 2007-11-07 | | Release date: | 2007-11-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2VG4
 | | Rv2361 native | | Descriptor: | UNDECAPRENYL PYROPHOSPHATE SYNTHETASE | | Authors: | Naismith, J.H, Wang, W, Dong, C. | | Deposit date: | 2007-11-08 | | Release date: | 2007-11-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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