1LBB
 
 | | Crystal structure of the GluR2 ligand binding domain mutant (S1S2J-N754D) in complex with kainate at 2.1 A resolution | | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamine receptor 2 | | Authors: | Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E. | | Deposit date: | 2002-04-02 | | Release date: | 2002-06-05 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
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1LB9
 | | Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with antagonist DNQX at 2.3 A resolution | | Descriptor: | 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION | | Authors: | Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E. | | Deposit date: | 2002-04-02 | | Release date: | 2002-06-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
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4MYS
 | | 1.4 Angstrom Crystal Structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase with SHCHC and Pyruvate | | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, GLYCEROL, ... | | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | | Deposit date: | 2013-09-28 | | Release date: | 2014-04-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.423 Å) | | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
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4MXD
 | | 1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) | | Descriptor: | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | | Deposit date: | 2013-09-26 | | Release date: | 2014-04-23 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
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4MYD
 | | 1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC | | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | | Deposit date: | 2013-09-27 | | Release date: | 2014-04-23 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.374 Å) | | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
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4I42
 | | E.coli. 1,4-dihydroxy-2-naphthoyl coenzyme A synthase (ecMenB) in complex with 1-hydroxy-2-naphthoyl-CoA | | Descriptor: | 1,2-ETHANEDIOL, 1,4-Dihydroxy-2-naphthoyl-CoA synthase, 1-hydroxy-2-naphthoyl-CoA, ... | | Authors: | Sun, Y, Song, H, Li, J, Li, Y, Jiang, M, Zhou, J, Guo, Z. | | Deposit date: | 2012-11-27 | | Release date: | 2013-05-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.848 Å) | | Cite: | Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily
Plos One, 8, 2013
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7DRB
 | | Crystal structure of plant receptor like protein RXEG1 with xyloglucanase XEG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | Deposit date: | 2020-12-27 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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7DRC
 | | Cryo-EM structure of plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 and BAK1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinosteroid insensitive 1-associated receptor kinase 1, ... | | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | Deposit date: | 2020-12-27 | | Release date: | 2022-06-22 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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7W3X
 | | Cryo-EM structure of plant receptor like protein RXEG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane-localized LRR receptor-like protein, ... | | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | Deposit date: | 2021-11-26 | | Release date: | 2022-06-22 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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7W3T
 | | Cryo-EM structure of plant receptor like kinase NbBAK1 in RXEG1-BAK1-XEG1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinosteroid insensitive 1-associated receptor kinase 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | Deposit date: | 2021-11-26 | | Release date: | 2022-06-22 | | Last modified: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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7W3V
 | | Plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | Deposit date: | 2021-11-26 | | Release date: | 2022-06-22 | | Last modified: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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4MG3
 | | Crystal Structural Analysis of 2A Protease from Coxsackievirus A16 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PENTAETHYLENE GLYCOL, Protease 2A, ... | | Authors: | Sun, Y, Wang, X, Dang, M, Yuan, S. | | Deposit date: | 2013-08-28 | | Release date: | 2014-03-26 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.798 Å) | | Cite: | An open conformation determined by a structural switch for 2A protease from coxsackievirus A16.
Protein Cell, 4, 2013
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2N1I
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2Q5X
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2Q5Y
 | | Crystal Structure of the C-terminal domain of hNup98 | | Descriptor: | Nuclear pore complex protein Nup96, Nuclear pore complex protein Nup98 | | Authors: | Sun, Y, Guo, H.C. | | Deposit date: | 2007-06-03 | | Release date: | 2008-10-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural constraints on autoprocessing of the human nucleoporin Nup98.
Protein Sci., 17, 2008
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2GP8
 | | NMR SOLUTION STRUCTURE OF THE COAT PROTEIN-BINDING DOMAIN OF BACTERIOPHAGE P22 SCAFFOLDING PROTEIN | | Descriptor: | PROTEIN (SCAFFOLDING PROTEIN) | | Authors: | Sun, Y, Parker, M.H, Weigele, P, Casjens, S, Prevelige Jr, P.E, Krishna, N.R. | | Deposit date: | 1999-05-11 | | Release date: | 1999-05-17 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.
J.Mol.Biol., 297, 2000
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7E5S
 | | SARS-CoV-2 S trimer with four-antibody cocktail complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | | Deposit date: | 2021-02-20 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms.
Cell Res., 31, 2021
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7E5R
 | | SARS-CoV-2 S trimer with three-antibody cocktail complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | | Deposit date: | 2021-02-20 | | Release date: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms.
Cell Res., 31, 2021
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8HXQ
 | | Nanobody1 in complex with human BCMA ECD | | Descriptor: | Nanobody1, Tumor necrosis factor receptor superfamily member 17 | | Authors: | Sun, Y, Zhang, B. | | Deposit date: | 2023-01-05 | | Release date: | 2024-01-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity.
Signal Transduct Target Ther, 8, 2023
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8HXR
 | | Nanobody2 in complex with human BCMA ECD | | Descriptor: | Nanobody2, Tumor necrosis factor receptor superfamily member 17 | | Authors: | Sun, Y, Zhang, B. | | Deposit date: | 2023-01-05 | | Release date: | 2024-01-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity.
Signal Transduct Target Ther, 8, 2023
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4Z2M
 | | Crystal structure of human SPT16 Mid-AID/H3-H4 tetramer FACT Histone complex | | Descriptor: | FACT complex subunit SPT16, Histone H3.1, Histone H4 | | Authors: | Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K. | | Deposit date: | 2015-03-30 | | Release date: | 2016-03-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.981 Å) | | Cite: | Integrated molecular mechanism directing nucleosome reorganization by human FACT.
Genes Dev., 30, 2016
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4Z2N
 | | Crystal structure of human FACT SPT16 middle domain | | Descriptor: | FACT complex subunit SPT16 | | Authors: | Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K. | | Deposit date: | 2015-03-30 | | Release date: | 2016-03-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.923 Å) | | Cite: | Integrated molecular mechanism directing nucleosome reorganization by human FACT.
Genes Dev., 30, 2016
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1TAB
 | | STRUCTURE OF THE TRYPSIN-BINDING DOMAIN OF BOWMAN-BIRK TYPE PROTEASE INHIBITOR AND ITS INTERACTION WITH TRYPSIN | | Descriptor: | BOWMAN-BIRK TYPE PROTEINASE INHIBITOR, TRYPSIN | | Authors: | Tsunogae, Y, Tanaka, I, Yamane, T, Kikkawa, J.-I, Ashida, T, Ishikawa, C, Watanabe, K, Nakamura, S, Takahashi, K. | | Deposit date: | 1990-10-15 | | Release date: | 1992-01-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the trypsin-binding domain of Bowman-Birk type protease inhibitor and its interaction with trypsin.
J.Biochem.(Tokyo), 100, 1986
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1WSF
 | | Co-crystal structure of E.coli RNase HI active site mutant (D134A*) with Mn2+ | | Descriptor: | MANGANESE (II) ION, Ribonuclease HI | | Authors: | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | Deposit date: | 2004-11-05 | | Release date: | 2005-02-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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1WSE
 | | Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ | | Descriptor: | MANGANESE (II) ION, Ribonuclease HI | | Authors: | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | Deposit date: | 2004-11-05 | | Release date: | 2005-02-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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