2VLA
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![BU of 2vla by Molmil](/molmil-images/mine/2vla) | Crystal structure of restriction endonuclease BpuJI recognition domain in complex with cognate DNA | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5'-D(*GP*GP*TP*AP*CP*CP*CP*GP*TP*GP *GP*A)-3', 5'-D(*TP*CP*CP*AP*CP*GP*GP*GP*TP*AP *CP*C)-3', ... | Authors: | Sukackaite, R, Grazulis, S, Bochtler, M, Siksnys, V. | Deposit date: | 2008-01-11 | Release date: | 2008-05-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The Recognition Domain of the Bpuji Restriction Endonuclease in Complex with Cognate DNA at 1.3-A Resolution. J.Mol.Biol., 378, 2008
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2ODH
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![BU of 2odh by Molmil](/molmil-images/mine/2odh) | Restriction Endonuclease BCNI in the Absence of DNA | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, R.BcnI | Authors: | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | Deposit date: | 2006-12-22 | Release date: | 2007-03-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA. J.Mol.Biol., 369, 2007
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2OA9
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![BU of 2oa9 by Molmil](/molmil-images/mine/2oa9) | Restriction endonuclease MvaI in the absence of DNA | Descriptor: | ACETATE ION, CADMIUM ION, CHLORIDE ION, ... | Authors: | Kaus-Drobek, M, Czapinska, H, Sokolowska, M, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | Deposit date: | 2006-12-15 | Release date: | 2007-02-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically. Nucleic Acids Res., 35, 2007
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2ODI
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![BU of 2odi by Molmil](/molmil-images/mine/2odi) | Restriction Endonuclease BCNI-Cognate DNA Substrate Complex | Descriptor: | 5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3', 5'-D(*CP*TP*CP*CP*GP*GP*GP*TP*TP*GP*T)-3', CALCIUM ION, ... | Authors: | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, C, Siksnys, V, Bochtler, M. | Deposit date: | 2006-12-22 | Release date: | 2007-03-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA. J.Mol.Biol., 369, 2007
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2OAA
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![BU of 2oaa by Molmil](/molmil-images/mine/2oaa) | Restriction endonuclease MvaI-cognate DNA substrate complex | Descriptor: | 5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3', CALCIUM ION, ... | Authors: | Kaus-Drobek, M, Czapinska, H, Sokolowska, M, Tamulaitis, G, Szczepanowski, R.H, Urbanke, K, Siksnys, V, Bochtler, M. | Deposit date: | 2006-12-15 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically. Nucleic Acids Res., 35, 2007
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8BF8
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![BU of 8bf8 by Molmil](/molmil-images/mine/8bf8) | ISDra2 TnpB in complex with reRNA | Descriptor: | Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB | Authors: | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D. | Deposit date: | 2022-10-24 | Release date: | 2023-04-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | TnpB structure reveals minimal functional core of Cas12 nuclease family. Nature, 616, 2023
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4RCT
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![BU of 4rct by Molmil](/molmil-images/mine/4rct) | Crystal structure of R-protein of NgoAVII restriction endonuclease | Descriptor: | Restriction endonuclease R.NgoVII | Authors: | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | Deposit date: | 2014-09-17 | Release date: | 2014-12-24 | Last modified: | 2014-12-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII. Nucleic Acids Res., 42, 2014
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4RD5
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![BU of 4rd5 by Molmil](/molmil-images/mine/4rd5) | Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA | Descriptor: | DNA (5'-D(*CP*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*GP*G)-3'), Restriction endonuclease R.NgoVII | Authors: | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | Deposit date: | 2014-09-18 | Release date: | 2014-12-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII. Nucleic Acids Res., 42, 2014
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4RDM
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![BU of 4rdm by Molmil](/molmil-images/mine/4rdm) | Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA | Descriptor: | DNA (5'-D(*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3)', DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*G)-3)', Restriction endonuclease R.NgoVII, ... | Authors: | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | Deposit date: | 2014-09-19 | Release date: | 2014-12-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII. Nucleic Acids Res., 42, 2014
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4RZL
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![BU of 4rzl by Molmil](/molmil-images/mine/4rzl) | |
6EK1
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![BU of 6ek1 by Molmil](/molmil-images/mine/6ek1) | Crystal structure of Type IIP restriction endonuclease PfoI | Descriptor: | 1,2-ETHANEDIOL, restriction endonuclease PfoI | Authors: | Tamulaitiene, G, Manakova, E, Jovaisaite, V, Grazulis, S, Siksnys, V. | Deposit date: | 2017-09-25 | Release date: | 2018-10-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family. Nucleic Acids Res., 47, 2019
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3HQF
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![BU of 3hqf by Molmil](/molmil-images/mine/3hqf) | Crystal structure of restriction endonuclease EcoRII N-terminal effector-binding domain in complex with cognate DNA | Descriptor: | 5'-D(*CP*GP*CP*CP*AP*GP*GP*GP*C)-3', 5'-D(*GP*CP*CP*CP*TP*GP*GP*CP*G)-3', Restriction endonuclease | Authors: | Golovenko, D, Manakova, E, Grazulis, S, Tamulaitiene, G, Siksnys, V. | Deposit date: | 2009-06-06 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII. Nucleic Acids Res., 37, 2009
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3HQG
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![BU of 3hqg by Molmil](/molmil-images/mine/3hqg) | Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA | Descriptor: | 5'-D(*TP*AP*GP*CP*CP*TP*GP*GP*TP*CP*GP*A)-3', 5'-D(*TP*CP*GP*AP*CP*CP*AP*GP*GP*CP*TP*A)-3', GLYCEROL, ... | Authors: | Golovenko, D, Manakova, E, Grazulis, S, Tamulaitiene, G, Siksnys, V. | Deposit date: | 2009-06-06 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII. Nucleic Acids Res., 37, 2009
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7AER
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![BU of 7aer by Molmil](/molmil-images/mine/7aer) | Rebuilt and re-refined PDB entry 5yep: tri-AMPylated Shewanella oneidensis HEPN toxin in complex with MNT antitoxin | Descriptor: | ADENOSINE MONOPHOSPHATE, Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | Authors: | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | Deposit date: | 2020-09-18 | Release date: | 2020-12-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation. Mol.Cell, 80, 2020
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7AE2
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![BU of 7ae2 by Molmil](/molmil-images/mine/7ae2) | Crystal structure of HEPN(H107A-Y109F) toxin in complex with MNT antitoxin | Descriptor: | HEPN toxin, MNT ANTITOXIN | Authors: | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | Deposit date: | 2020-09-17 | Release date: | 2020-12-30 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation. Mol.Cell, 80, 2020
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7AE6
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![BU of 7ae6 by Molmil](/molmil-images/mine/7ae6) | Crystal structure of di-AMPylated HEPN(R102A) toxin | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, HEPN toxin | Authors: | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | Deposit date: | 2020-09-17 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation. Mol.Cell, 80, 2020
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1CFR
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![BU of 1cfr by Molmil](/molmil-images/mine/1cfr) | |
1D02
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![BU of 1d02 by Molmil](/molmil-images/mine/1d02) | CRYSTAL STRUCTURE OF MUNI RESTRICTION ENDONUCLEASE IN COMPLEX WITH COGNATE DNA | Descriptor: | DNA (5'-D(*GP*CP*CP*AP*AP*TP*TP*GP*GP*C)-3'), TYPE II RESTRICTION ENZYME MUNI | Authors: | Deibert, M, Grazulis, S, Janulaitis, A, Siksnys, V, Huber, R. | Deposit date: | 1999-09-08 | Release date: | 2000-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of MunI restriction endonuclease in complex with cognate DNA at 1.7 A resolution. EMBO J., 18, 1999
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1FIU
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![BU of 1fiu by Molmil](/molmil-images/mine/1fiu) | TETRAMERIC RESTRICTION ENDONUCLEASE NGOMIV IN COMPLEX WITH CLEAVED DNA | Descriptor: | ACETIC ACID, DNA (5'-D(*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*CP*GP*C)-3'), ... | Authors: | Deibert, M, Grazulis, S, Sasnauskas, G, Siksnys, V, Huber, R. | Deposit date: | 2000-08-07 | Release date: | 2001-02-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat.Struct.Biol., 7, 2000
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6QXT
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![BU of 6qxt by Molmil](/molmil-images/mine/6qxt) | Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-08 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QY3
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![BU of 6qy3 by Molmil](/molmil-images/mine/6qy3) | Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-08 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QXF
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![BU of 6qxf by Molmil](/molmil-images/mine/6qxf) | Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-07 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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3SSD
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![BU of 3ssd by Molmil](/molmil-images/mine/3ssd) | DNA binding domain of restriction endonuclease bound to DNA | Descriptor: | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*A*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*T*GP*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*GP*C)-3') | Authors: | Sukackaite, R, Grazulis, S, Siksnys, V. | Deposit date: | 2011-07-08 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine. Nucleic Acids Res., 40, 2012
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3SSE
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![BU of 3sse by Molmil](/molmil-images/mine/3sse) | DNA binding domain of restriction endonuclease bound to DNA | Descriptor: | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*A*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*T*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3') | Authors: | Sukackaite, R, Grazulis, S, Siksnys, V. | Deposit date: | 2011-07-08 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine. Nucleic Acids Res., 40, 2012
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3SSC
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![BU of 3ssc by Molmil](/molmil-images/mine/3ssc) | DNA binding domain of restriction endonuclease bound to DNA | Descriptor: | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*AP*GP*CP*TP*AP*(5CM)P*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*GP*C)-3') | Authors: | Sukackaite, R, Grazulis, S, Siksnys, V. | Deposit date: | 2011-07-08 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine. Nucleic Acids Res., 40, 2012
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