7XX4
 
 | designed glycosyltransferase | Descriptor: | Oleandomycin glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Lu, M, Wu, X. | Deposit date: | 2022-05-28 | Release date: | 2023-06-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Design of a chimeric glycosyltransferase OleD for the site-specific O-monoglycosylation of 3-hydroxypyridine in nosiheptide. Microb Biotechnol, 16, 2023
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9D7X
 
 | The spm-bound structure | Descriptor: | Green fluorescence protein,MFS-type transporter SLC18B1,membrane protein with spm, SPERMINE | Authors: | Lu, M, Liu, B. | Deposit date: | 2024-08-17 | Release date: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure and mechanism of human vesicular polyamine transporter. Nat Commun, 16, 2025
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9D7U
 
 | The low pH structure | Descriptor: | Green fluorescence protein,MFS-type transporter SLC18B1,membrane protein and fusion partners | Authors: | Lu, M, Liu, B. | Deposit date: | 2024-08-17 | Release date: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Structure and mechanism of human vesicular polyamine transporter. Nat Commun, 16, 2025
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9D7W
 
 | The TBZ-bound structure | Descriptor: | Green fluorescence protein,MFS-type transporter SLC18B1,membrane protein with TBZ, tetrabenazine | Authors: | Lu, M, Liu, B. | Deposit date: | 2024-08-17 | Release date: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and mechanism of human vesicular polyamine transporter. Nat Commun, 16, 2025
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9D7V
 
 | The spd-bound structure | Descriptor: | Green fluorescence protein,MFS-type transporter SLC18B1,membrane protein spd, SPERMIDINE | Authors: | Lu, M, Liu, B. | Deposit date: | 2024-08-17 | Release date: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and mechanism of human vesicular polyamine transporter. Nat Commun, 16, 2025
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6VS0
 
 | protein B | Descriptor: | CHLORAMPHENICOL, Multidrug transporter MdfA, PRASEODYMIUM ION | Authors: | Lu, M, Lu, M.M. | Deposit date: | 2020-02-10 | Release date: | 2020-06-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6VS2
 
 | protein D | Descriptor: | LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA, PRASEODYMIUM ION | Authors: | Lu, M, Lu, M.M. | Deposit date: | 2020-02-10 | Release date: | 2020-06-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6VRZ
 
 | protein A | Descriptor: | CHLORAMPHENICOL, Multidrug transporter MdfA, PRASEODYMIUM ION | Authors: | Lu, M, Lu, M.M. | Deposit date: | 2020-02-10 | Release date: | 2020-06-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6VS1
 
 | protein C | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Multidrug transporter MdfA, PRASEODYMIUM ION | Authors: | Lu, M, Lu, M.M. | Deposit date: | 2020-02-10 | Release date: | 2020-06-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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5C6N
 
 | protein A | Descriptor: | BH2163 protein | Authors: | Lu, M. | Deposit date: | 2015-06-23 | Release date: | 2015-09-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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5C6P
 
 | protein C | Descriptor: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D | Authors: | Lu, M. | Deposit date: | 2015-06-23 | Release date: | 2015-09-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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5C6O
 
 | protein B | Descriptor: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, BH2163 protein | Authors: | Lu, M. | Deposit date: | 2015-06-23 | Release date: | 2015-09-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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6OOM
 
 | PROTEIN A | Descriptor: | LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA, PRASEODYMIUM ION | Authors: | Lu, M. | Deposit date: | 2019-04-23 | Release date: | 2019-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
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6OOP
 
 | protein B | Descriptor: | 1,1'-dimethyl-4,4'-bipyridin-1-ium, Multidrug transporter MdfA, PRASEODYMIUM ION | Authors: | Lu, M. | Deposit date: | 2019-04-23 | Release date: | 2019-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
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6OOQ
 
 | protein C | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Multidrug transporter MdfA | Authors: | Lu, M. | Deposit date: | 2019-04-23 | Release date: | 2019-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
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1I5Y
 
 | HIV-1 GP41 CORE | Descriptor: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | Authors: | Liu, J, Lu, M. | Deposit date: | 2001-03-01 | Release date: | 2002-09-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
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4XWW
 
 | Crystal structure of RNase J complexed with RNA | Descriptor: | DR2417, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y. | Deposit date: | 2015-01-29 | Release date: | 2015-12-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J Nucleic Acids Res., 43, 2015
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4XWT
 
 | Crystal structure of RNase J complexed with UMP | Descriptor: | DR2417, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y. | Deposit date: | 2015-01-29 | Release date: | 2015-12-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J Nucleic Acids Res., 43, 2015
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1I5X
 
 | HIV-1 GP41 CORE | Descriptor: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | Authors: | Liu, J, Lu, M. | Deposit date: | 2001-03-01 | Release date: | 2002-09-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
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8H4H
 
 | The apo structure of Aspergillomarasmine A synthetase | Descriptor: | Rhodanese domain-containing protein | Authors: | Lu, M, Zhang, J, Wang, Z, Han, L. | Deposit date: | 2022-10-10 | Release date: | 2023-10-18 | Last modified: | 2025-04-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Investigation of AMA Synthase from Pyrenophora teres f. teres 0-1 for the Synthesis of Aspergillomarasmine A Analogues and Non-Canonical Amino Acids Adv.Synth.Catal., 366, 2024
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8H4Q
 
 | Aspergillomarasmine A biosynthese complex with OPS | Descriptor: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Rhodanese domain-containing protein | Authors: | Lu, M, Zhang, J, Wang, Z, Han, L. | Deposit date: | 2022-10-11 | Release date: | 2023-10-18 | Last modified: | 2025-04-30 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Investigation of AMA Synthase from Pyrenophora teres f. teres 0-1 for the Synthesis of Aspergillomarasmine A Analogues and Non-Canonical Amino Acids Adv.Synth.Catal., 366, 2024
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5ULD
 
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5ULE
 
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5UL9
 
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5Z9J
 
 | Identification of the functions of unusual cytochrome p450-like monooxygenases involved in microbial secondary metablism | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like enzyme, TRIS(HYDROXYETHYL)AMINOMETHANE | Authors: | Lu, M, Lin, L, Zhang, C, Chen, Y. | Deposit date: | 2018-02-03 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases. Chembiochem, 2020
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