8U5Z
 
 | | Structure of Mango II variant aptamer bound to T01-7M-B | | Descriptor: | 2-[(E)-(1,7-dimethylquinolin-4(1H)-ylidene)methyl]-3-{2,16-dioxo-20-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium, Mango II variant, POTASSIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2023-09-13 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Mango II variant aptamer bound to T01-7M-B
To Be Published
|
|
8U5J
 | | Structure of Mango III variant aptamer bound to T01-07M-B | | Descriptor: | 2-[(E)-(1,7-dimethylquinolin-4(1H)-ylidene)methyl]-3-{2,16-dioxo-20-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium, DIMETHYL SULFOXIDE, Mango III variant, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2023-09-12 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Mango III variant aptamer bound to T01-07M-B
To Be Published
|
|
7L0Z
 | | Spinach variant bound to DFHBI-1T | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Truong, L, Trachman, R.J, Ferre-D'Amare, A.R. | | Deposit date: | 2020-12-13 | | Release date: | 2021-05-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET.
Rna, 27, 2021
|
|
8F5G
 | | NusG-RNA complex | | Descriptor: | DI(HYDROXYETHYL)ETHER, RNA, Transcription termination/antitermination protein NusG | | Authors: | Elghondakly, A.T, Ferre-D'Amare, A.R. | | Deposit date: | 2022-11-14 | | Release date: | 2023-11-22 | | Last modified: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Major-groove sequence-specific RNA recognition by LoaP, a paralog of transcription elongation factor NusG.
Structure, 2024
|
|
8FI8
 | |
8FHZ
 | | Structure of Lettuce aptamer bound to DFHO | | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2022-12-15 | | Release date: | 2023-05-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
|
|
8FHV
 | | Structure of Lettuce aptamer bound to DFHBI-1T with thallium I ions | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2022-12-15 | | Release date: | 2023-05-10 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
|
|
8FI2
 | | Structure of Lettuce C20T bound to DFHBI-1T | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2022-12-15 | | Release date: | 2023-05-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
|
|
8FI1
 | | Structure of Lettuce C20G bound to DFHO | | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2022-12-15 | | Release date: | 2023-05-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
|
|
8FI0
 | |
8FI7
 | | Structure of Lettuce C20T bound to DFHO | | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2022-12-15 | | Release date: | 2023-05-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
|
|
8FHX
 | | Structure of Lettuce aptamer bound to DFHBI-1T | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ... | | Authors: | Passalacqua, L.F.M, Ferre-D'Amare, A.R. | | Deposit date: | 2022-12-15 | | Release date: | 2023-05-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
|
|
8U5R
 | |
8U60
 | |
8U5K
 | |
7KVT
 | | Crystal structure of Squash RNA aptamer in complex with DFHBI-1T with iridium (III) ions | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ... | | Authors: | Truong, L, Ferre-D'Amare, A.R. | | Deposit date: | 2020-11-28 | | Release date: | 2022-01-19 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.
Nat.Chem.Biol., 18, 2022
|
|
7KVU
 | | Crystal structure of Squash RNA aptamer in complex with DFHBI-1T | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Truong, L, Ferre-D'Amare, A.R. | | Deposit date: | 2020-11-28 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.
Nat.Chem.Biol., 18, 2022
|
|
3V7E
 | | Crystal structure of YbxF bound to the SAM-I riboswitch aptamer | | Descriptor: | COBALT HEXAMMINE(III), MAGNESIUM ION, Ribosome-associated protein L7Ae-like, ... | | Authors: | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | | Deposit date: | 2011-12-21 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops.
Rna, 18, 2012
|
|
3CUN
 | | Aminoacyl-tRNA synthetase ribozyme | | Descriptor: | COBALT (II) ION, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Xiao, H, Murakami, H, Suga, H, Ferre-D'Amare, A.R. | | Deposit date: | 2008-04-16 | | Release date: | 2008-06-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme.
Nature, 454, 2008
|
|
3CUL
 | | Aminoacyl-tRNA synthetase ribozyme | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, RNA (92-MER), ... | | Authors: | Xiao, H, Murakami, H, Suga, H, Ferre-D'Amare, A.R. | | Deposit date: | 2008-04-16 | | Release date: | 2008-06-24 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme.
Nature, 454, 2008
|
|
3B4B
 | |
3B4C
 | |
3B4A
 | |
1NU4
 | | U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix | | Descriptor: | MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain | | Authors: | Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R. | | Deposit date: | 2003-01-30 | | Release date: | 2003-02-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
3V7Q
 | | Crystal structure of B. subtilis YlxQ at 1.55 A resolution | | Descriptor: | CITRIC ACID, POTASSIUM ION, Probable ribosomal protein ylxQ | | Authors: | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | | Deposit date: | 2011-12-21 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops.
Rna, 18, 2012
|
|
