3UMW
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![BU of 3umw by Molmil](/molmil-images/mine/3umw) | Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indazol-3-yl)methylene]-6-methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one | Descriptor: | (2Z)-2-(1H-indazol-3-ylmethylidene)-6-methoxy-7-(piperazin-1-ylmethyl)-1-benzofuran-3(2H)-one, GLYCEROL, Proto-oncogene serine/threonine-protein kinase pim-1, ... | Authors: | Parker, L.J, Handa, N, Yokoyama, S. | Deposit date: | 2011-11-14 | Release date: | 2012-10-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound. J.Med.Chem., 55, 2012
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3WAW
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![BU of 3waw by Molmil](/molmil-images/mine/3waw) | Crystal Structure of Autotaxin in Complex with 2BoA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.954 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAY
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![BU of 3way by Molmil](/molmil-images/mine/3way) | Crystal Structure of Autotaxin in Complex with 4BoA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.746 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAX
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![BU of 3wax by Molmil](/molmil-images/mine/3wax) | Crystal Structure of Autotaxin in Complex with 3BoA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAV
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![BU of 3wav by Molmil](/molmil-images/mine/3wav) | Crystal Structure of Autotaxin in Complex with Compound 10 | Descriptor: | (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-09 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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7F22
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![BU of 7f22 by Molmil](/molmil-images/mine/7f22) | L-lactate oxidase with pyruvate | Descriptor: | FLAVIN MONONUCLEOTIDE, L-lactate oxidase, PYRUVIC ACID | Authors: | Morimoto, Y, Inaka, K. | Deposit date: | 2021-06-10 | Release date: | 2022-03-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Dynamic interactions in the l-lactate oxidase active site facilitate substrate binding at pH4.5. Biochem.Biophys.Res.Commun., 568, 2021
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7F21
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![BU of 7f21 by Molmil](/molmil-images/mine/7f21) | L-lactate oxidase with D-lactate | Descriptor: | FLAVIN MONONUCLEOTIDE, L-lactate oxidase, LACTIC ACID | Authors: | Morimoto, Y, Inaka, K. | Deposit date: | 2021-06-10 | Release date: | 2022-03-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Dynamic interactions in the l-lactate oxidase active site facilitate substrate binding at pH4.5. Biochem.Biophys.Res.Commun., 568, 2021
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7F20
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![BU of 7f20 by Molmil](/molmil-images/mine/7f20) | L-lactate oxidase with L-lactate | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, FLAVIN MONONUCLEOTIDE, L-lactate oxidase | Authors: | Morimoto, Y, Inaka, K. | Deposit date: | 2021-06-10 | Release date: | 2022-03-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Dynamic interactions in the l-lactate oxidase active site facilitate substrate binding at pH4.5. Biochem.Biophys.Res.Commun., 568, 2021
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7F1Y
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![BU of 7f1y by Molmil](/molmil-images/mine/7f1y) | L-lactate oxidase without substrate | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FLAVIN MONONUCLEOTIDE, ... | Authors: | Morimoto, Y, Inaka, K. | Deposit date: | 2021-06-10 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Dynamic interactions in the l-lactate oxidase active site facilitate substrate binding at pH4.5. Biochem.Biophys.Res.Commun., 568, 2021
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