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6VHJ
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BU of 6vhj by Molmil
Solution NMR of Prochlorosin 1.1 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 1.1
Authors:Bobeica, S.C, van der Donk, W.A, Tang, W.
Deposit date:2020-01-09
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VJQ
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BU of 6vjq by Molmil
Solution NMR structure of Prochlorosin 2.1 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.1
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L.
Deposit date:2020-01-16
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VLJ
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BU of 6vlj by Molmil
Solution NMR of Prochlorosin 2.8 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.8
Authors:Bobeica, S.C, Acedo, J.Z, van der Donk, W.A, Zhu, L.
Deposit date:2020-01-24
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
7JVF
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BU of 7jvf by Molmil
Solution NMR structure of Prochlorosin 2.10 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.10
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L.
Deposit date:2020-08-21
Release date:2020-09-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
7JU9
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BU of 7ju9 by Molmil
Solution NMR structure of Prochlorosin 2.11 (Pcn2.11) produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.11
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L.
Deposit date:2020-08-19
Release date:2020-09-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VGT
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BU of 6vgt by Molmil
Solution NMR structure of enterococcal cytolysin L (CylLL") produced by Enterococcus faecalis
Descriptor: cytolysin L
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L, Tang, W.
Deposit date:2020-01-08
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VE9
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BU of 6ve9 by Molmil
Solution NMR structure of enterococcal cytolysin S (CylLS") produced by Enterococcus faecalis
Descriptor: enterococcal cytolysin S
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L, Tang, W.
Deposit date:2019-12-30
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
2MIJ
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BU of 2mij by Molmil
NMR structure of the S-linked glycopeptide sublancin 168
Descriptor: SPBc2 prophage-derived bacteriocin sublancin-168, beta-D-glucopyranose
Authors:Garcia De Gonzalo, C.V, Zhu, L, Oman, T.J, van der Donk, W.A.
Deposit date:2013-12-13
Release date:2014-03-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of the s-linked glycopeptide sublancin 168.
Acs Chem.Biol., 9, 2014
6PO6
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BU of 6po6 by Molmil
MicroED Structure of a Natural Product VFAThiaGlu
Descriptor: YFAThiaGlu
Authors:Halaby, S, Gonen, T, Ting, C.P, Funk, M.A, van der Donk, W.A.
Deposit date:2019-07-03
Release date:2019-08-07
Last modified:2023-11-15
Method:ELECTRON CRYSTALLOGRAPHY (1 Å)
Cite:Use of a scaffold peptide in the biosynthesis of amino acid-derived natural products.
Science, 365, 2019
6PQF
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BU of 6pqf by Molmil
Solution structure of OlvA(BCS)
Descriptor: OlvA(BCS)
Authors:Acedo, J.Z, van der Donk, W.A.
Deposit date:2019-07-09
Release date:2019-10-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:O-Methyltransferase-Mediated Incorporation of a beta-Amino Acid in Lanthipeptides.
J.Am.Chem.Soc., 141, 2019
6PQG
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BU of 6pqg by Molmil
Solution structure of OlvA(BC)
Descriptor: OlvA(BC)
Authors:Acedo, J.Z, van der Donk, W.A.
Deposit date:2019-07-09
Release date:2019-10-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:O-Methyltransferase-Mediated Incorporation of a beta-Amino Acid in Lanthipeptides.
J.Am.Chem.Soc., 141, 2019
6WQ1
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BU of 6wq1 by Molmil
Eukaryotic LanCL2 protein
Descriptor: LanC-like protein 2, ZINC ION
Authors:Nair, S.K, Garg, N.
Deposit date:2020-04-28
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome.
Cell, 184, 2021
6EC7
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BU of 6ec7 by Molmil
Glutamylation domain, TbtB, from thiomuracin biosynthesis
Descriptor: Lantibiotic dehydratase domain protein
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-08-07
Release date:2019-08-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc.Natl.Acad.Sci.USA, 116, 2019
4WD9
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BU of 4wd9 by Molmil
Crystal structure of tRNA-dependent lantibiotic dehydratase NisB in complex with NisA leader peptide
Descriptor: Nisin biosynthesis protein NisB
Authors:Hao, Y, Nair, S.K.
Deposit date:2014-09-08
Release date:2014-10-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Nature, 517, 2015
2G0D
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BU of 2g0d by Molmil
Nisin cyclase
Descriptor: Nisin biosynthesis protein nisC, ZINC ION
Authors:Nair, S.K.
Deposit date:2006-02-12
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis
Science, 311, 2006
2G02
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BU of 2g02 by Molmil
Nisin cyclase
Descriptor: Nisin biosynthesis protein nisC, ZINC ION
Authors:Nair, S.K.
Deposit date:2006-02-10
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis
Science, 311, 2006
7RTY
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BU of 7rty by Molmil
Crystal Structure of PsfC from Pseudomonas syringae PB-5123
Descriptor: FE (II) ION, PsfC
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2021-08-16
Release date:2021-09-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.963 Å)
Cite:Biosynthesis of fosfomycin in pseudomonads reveals an unexpected enzymatic activity in the metallohydrolase superfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
8HCI
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BU of 8hci by Molmil
Crystal structure of a holoenzyme Fe-free TglHI for Pseudomonas syringae Peptidyl (S) 2-mercaptoglycine biosynthesis
Descriptor: DUF692 family protein, RiPP Recognition protein
Authors:Cheng, W, Zheng, Y.H, Fu, X.L.
Deposit date:2022-11-01
Release date:2023-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.399 Å)
Cite:Structures of the holoenzyme TglHI required for 3-thiaglutamate biosynthesis.
Structure, 31, 2023
8HI8
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BU of 8hi8 by Molmil
Crystal structure of a holoenzyme TglHI with three Fe ions for Pseudomonas syringae Peptidyl (S) 2-mercaptoglycine biosynthesis
Descriptor: DUF692 family protein, FE (III) ION, RiPP Recognition Protein
Authors:Cheng, W, Zheng, Y.H, Fu, X.L.
Deposit date:2022-11-18
Release date:2023-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of the holoenzyme TglHI required for 3-thiaglutamate biosynthesis.
Structure, 31, 2023
8HI7
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BU of 8hi7 by Molmil
Crystal structure of a holoenzyme TglHI with two Fe irons for Pseudomonas syringae Peptidyl (S) 2-mercaptoglycine biosynthesis
Descriptor: DUF692 family protein, FE (III) ION, RiPP Recognition protein
Authors:Cheng, W, Zheng, Y.H, Fu, X.L.
Deposit date:2022-11-18
Release date:2023-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structures of the holoenzyme TglHI required for 3-thiaglutamate biosynthesis.
Structure, 31, 2023
4YAR
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BU of 4yar by Molmil
2-Hydroxyethylphosphonate dioxygenase (HEPD) E176H
Descriptor: 2-hydroxyethylphosphonate dioxygenase, ACETATE ION, CADMIUM ION, ...
Authors:Chekan, J.R, Nair, S.K.
Deposit date:2015-02-17
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase.
J.Am.Chem.Soc., 137, 2015
4ZOQ
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BU of 4zoq by Molmil
Crystal Structure of a Lanthipeptide Protease
Descriptor: Intracellular serine protease
Authors:Dong, S.H, Nair, S.K.
Deposit date:2015-05-06
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage.
Chem Sci, 6, 2015
6EC8
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BU of 6ec8 by Molmil
Glutamylation domain, TbtB, from thiomuracin biosynthesis bound to 5'-phosphodesmethylglutamycin
Descriptor: 3'-deoxy-3'-[(L-alpha-glutamyl)amino]adenosine 5'-(dihydrogen phosphate), Lantibiotic dehydratase domain protein
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-08-07
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc.Natl.Acad.Sci.USA, 116, 2019
8CWX
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BU of 8cwx by Molmil
NMR structure of a Stapled Lanthipeptide Natural Product
Descriptor: Lanthipeptide Natural Product mSmoAc
Authors:Pei, Z, Zhu, L, Nair, S.K.
Deposit date:2022-05-19
Release date:2022-10-12
Method:SOLUTION NMR
Cite:Class V Lanthipeptide Cyclase Directs the Biosynthesis of a Stapled Peptide Natural Product.
J.Am.Chem.Soc., 144, 2022
8CZK
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BU of 8czk by Molmil
Human LanCL1 bound to GSH and Dhb-Erk peptide
Descriptor: Deb-Erk peptide, GLUTATHIONE, Glutathione S-transferase LANCL1, ...
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2022-05-24
Release date:2023-01-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The mechanism of thia-Michael addition catalyzed by LanC enzymes.
Proc.Natl.Acad.Sci.USA, 120, 2023

 

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