7N2P
 
 | | AS4.3-RNASEH2b-HLA*B27 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | | Deposit date: | 2021-05-29 | | Release date: | 2022-12-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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4ZYL
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2BQ0
 | | 14-3-3 Protein Beta (Human) | | Descriptor: | 14-3-3 BETA/ALPHA | | Authors: | Yang, X, Elkins, J.M, Fedorov, O, Longman, E.J, Sobott, L, Ball, L.J, Sundstrom, M, Arrowsmith, C, Edwards, A, Doyle, D.A. | | Deposit date: | 2005-04-26 | | Release date: | 2005-05-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
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2BR9
 | | 14-3-3 Protein Epsilon (Human) Complexed to Peptide | | Descriptor: | 14-3-3 PROTEIN EPSILON, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS | | Authors: | Yang, X, Elkins, J.M, Soundararajan, M, Fedorov, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A. | | Deposit date: | 2005-05-03 | | Release date: | 2005-05-12 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
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6U9E
 | | Structure of PdpA-VgrG Complex, Lidless | | Descriptor: | PdpA, VgrG | | Authors: | Yang, X, Clemens, D.L, Lee, B.-Y, Cui, Y, Zhou, Z.H, Horwitz, M.A. | | Deposit date: | 2019-09-08 | | Release date: | 2019-10-23 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.21 Å) | | Cite: | Atomic Structure of the Francisella T6SS Central Spike Reveals a Unique alpha-Helical Lid and a Putative Cargo.
Structure, 27, 2019
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1JBS
 | | Crystal structure of ribotoxin restrictocin and a 29-mer SRD RNA analog | | Descriptor: | 29-mer sarcin/ricin domain RNA analog, POTASSIUM ION, restrictocin | | Authors: | Yang, X, Gerczei, T, Glover, L, Correll, C.C. | | Deposit date: | 2001-06-06 | | Release date: | 2001-10-26 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping.
Nat.Struct.Biol., 8, 2001
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1JBT
 | | CRYSTAL STRUCTURE OF RIBOTOXIN RESTRICTOCIN COMPLEXED WITH A 29-MER SARCIN/RICIN DOMAIN RNA ANALOG | | Descriptor: | 29-MER SARCIN/RICIN DOMAIN RNA ANALOG, POTASSIUM ION, RESTRICTOCIN | | Authors: | Yang, X, Gerczei, T, Glover, L, Correll, C.C. | | Deposit date: | 2001-06-06 | | Release date: | 2001-10-26 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping.
Nat.Struct.Biol., 8, 2001
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1JBR
 | | Crystal Structure of the Ribotoxin Restrictocin and a 31-mer SRD RNA Inhibitor | | Descriptor: | 31-mer SRD RNA analog, 5'-R(*GP*CP*GP*CP*UP*CP*CP*UP*CP*AP*GP*UP*AP*CP*GP*AP*GP*(A23))-3', 5'-R(*GP*GP*AP*AP*CP*CP*GP*GP*AP*GP*CP*GP*C)-3', ... | | Authors: | Yang, X, Gerczei, T, Glover, L, Correll, C.C. | | Deposit date: | 2001-06-06 | | Release date: | 2001-10-26 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping.
Nat.Struct.Biol., 8, 2001
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6U9G
 | | Structure of Francisella PdpA-VgrG Complex, half-lidded | | Descriptor: | PdpA, VgrG | | Authors: | Yang, X, Clemens, D.L, Lee, B.-Y, Cui, Y, Zhou, Z.H, Horwitz, M.A. | | Deposit date: | 2019-09-08 | | Release date: | 2019-10-23 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Atomic Structure of the Francisella T6SS Central Spike Reveals a Unique alpha-Helical Lid and a Putative Cargo.
Structure, 27, 2019
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6U9F
 | | Structure of Francisella PdpA-VgrG Complex, Lidded | | Descriptor: | PdpA, VgrG | | Authors: | Yang, X, Clemens, D.L, Lee, B.-Y, Cui, Y.X, Horwitz, M.A, Zhou, Z.H. | | Deposit date: | 2019-09-08 | | Release date: | 2019-10-23 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.35 Å) | | Cite: | Atomic Structure of the Francisella T6SS Central Spike Reveals a Unique alpha-Helical Lid and a Putative Cargo.
Structure, 27, 2019
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5YGE
 | | ArgA complexed with AceCoA and glutamate | | Descriptor: | ACETYL COENZYME *A, Amino-acid acetyltransferase, CACODYLIC ACID, ... | | Authors: | Yang, X, Wu, L, Ran, Y, Xu, A, Zhang, B, Yang, X, Zhang, R, Rao, Z, Li, J. | | Deposit date: | 2017-09-22 | | Release date: | 2017-10-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.039 Å) | | Cite: | Crystal structure of l-glutamate N-acetyltransferase ArgA from Mycobacterium tuberculosis
Biochim. Biophys. Acta, 1865, 2017
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1CX5
 | | ANTISENSE DNA/RNA HYBRID CONTAINING MODIFIED BACKBONE | | Descriptor: | 5'-D(*CP*GP*CP*GP*TP*T*(MMT)P*TP*GP*CP*GP*C), 5'-R(*GP*CP*GP*CP*AP*AP*AP*AP*CP*GP*CP*G) | | Authors: | Yang, X, Han, X, Cross, C, Sanghvi, Y, Gao, X. | | Deposit date: | 1999-08-28 | | Release date: | 1999-09-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure of an antisense DNA.RNA hybrid duplex containing a 3'-CH(2)N(CH(3))-O-5' or an MMI backbone linker.
Biochemistry, 38, 1999
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9CA1
 | | Human TOP3B-TDRD3 core complex in DNA religation state | | Descriptor: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-16 | | Release date: | 2024-07-17 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9C9Y
 | | Human TOP3B-TDRD3 core complex in DNA pre-cleavage state | | Descriptor: | DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*T)-3'), DNA topoisomerase 3-beta-1, MANGANESE (II) ION, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-16 | | Release date: | 2024-07-17 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CA0
 | | Human TOP3B-TDRD3 core complex in DNA post-cleavage state | | Descriptor: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-16 | | Release date: | 2024-07-17 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CAH
 | | Human TOP3B-TDRD3 complex | | Descriptor: | DNA topoisomerase 3-beta-1, MANGANESE (II) ION, Tudor domain-containing protein 3, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-17 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CAK
 | | Human TOP3B-TDRD3 core complex in DNA rejoining state with ssDNA 5'-GACAGATATT-3 | | Descriptor: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*GP*AP*CP*AP*GP*AP*T)-3'), DNA topoisomerase 3-beta-1, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-17 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CAL
 | | Human TOP3B-TDRD3 core complex in post-cleavage state with ssDNA 5'-ACAGATATT-3 | | Descriptor: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*GP*AP*CP*AP*GP*AP*T)-3'), DNA topoisomerase 3-beta-1, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-17 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CAG
 | | Human TOP3B-TDRD3 core complex in RNA pre-cleavage state | | Descriptor: | DNA topoisomerase 3-beta-1, MANGANESE (II) ION, RNA (5'-R(P*AP*CP*UP*AP*AP*AP*AP*U)-3'), ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-17 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CAJ
 | | Human TOP3B-TDRD3 core complex in pre-cleavage state with ssDNA 5'-ACAGATATT-3 | | Descriptor: | DNA (5'-D(P*AP*CP*AP*GP*AP*TP*AP*TP*T)-3'), DNA topoisomerase 3-beta-1, MANGANESE (II) ION, ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-17 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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9CA4
 | | Human TOP3B-TDRD3 core complex in RNA rejoining state | | Descriptor: | DNA topoisomerase 3-beta-1, MANGANESE (II) ION, RNA (5'-R(*AP*U)-3'), ... | | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | | Deposit date: | 2024-06-16 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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8CX4
 | | TCR-antigen complex AS8.4-YEIH-HLA*B27 | | Descriptor: | AS8.4a, AS8.4b, Beta-2-microglobulin, ... | | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | | Deposit date: | 2022-05-19 | | Release date: | 2022-12-07 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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9C9W
 | | Dimerized human TOP3B-TDRD3 core complex with a DNA mismatch bubble | | Descriptor: | DNA (38-MER), DNA (5'-D(*AP*TP*TP*GP*GP*AP*GP*TP*TP*CP*AP*TP*GP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*CP*AP*GP*AP*TP*CP*AP*GP*AP*AP*TP*GP*AP*AP*TP*AP*TP*AP*CP*TP*AP*AP*A)-3'), ... | | Authors: | Yang, X. | | Deposit date: | 2024-06-16 | | Release date: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.
Nat Commun, 16, 2025
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4YN7
 | | Non-oxidized YfiR | | Descriptor: | SULFATE ION, YfiR | | Authors: | Yang, X, Jiang, T. | | Deposit date: | 2015-03-09 | | Release date: | 2015-04-22 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states
Biochem.Biophys.Res.Commun., 461, 2015
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3LRA
 | | Structural Basis for Assembling a Human Tripartite Complex Dlg1-MPP7-Mals3 | | Descriptor: | Disks large homolog 1, MAGUK p55 subfamily member 7, Protein lin-7 homolog C | | Authors: | Yang, X, Xie, X, Shen, Y, Long, J. | | Deposit date: | 2010-02-10 | | Release date: | 2010-11-17 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural basis for tandem L27 domain-mediated polymerization
Faseb J., 24, 2010
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