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7EIQ
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BU of 7eiq by Molmil
Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 4S
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, MAGNESIUM ION
Authors:Takashima, M, Miyanaga, A, Eguchi, T.
Deposit date:2021-03-31
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides.
Glycobiology, 31, 2021
7EIR
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BU of 7eir by Molmil
Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 6S
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, GLYCEROL, ...
Authors:Takashima, M, Miyanaga, A, Eguchi, T.
Deposit date:2021-03-31
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides.
Glycobiology, 31, 2021
7EIP
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BU of 7eip by Molmil
Crystal structure of ligand-free chondroitin ABC lyase I
Descriptor: ACETATE ION, Chondroitin sulfate ABC endolyase, MAGNESIUM ION
Authors:Takashima, M, Miyanaga, A, Eguchi, T.
Deposit date:2021-03-31
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides.
Glycobiology, 31, 2021
7EIS
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BU of 7eis by Molmil
Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 0S
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, MAGNESIUM ION
Authors:Takashima, M, Miyanaga, A, Eguchi, T.
Deposit date:2021-03-31
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides.
Glycobiology, 31, 2021
7YKE
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BU of 7yke by Molmil
Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 4,6-sulfate
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4,6-di-O-sulfo-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, MAGNESIUM ION
Authors:Takashima, M, Watanabe, I, Miyanaga, A, Eguchi, T.
Deposit date:2022-07-22
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity.
Febs J., 290, 2023
6J5L
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BU of 6j5l by Molmil
Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e
Descriptor: High affinity nerve growth factor receptor, N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide
Authors:Kensuke, A, Kazutaka, I.
Deposit date:2019-01-11
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain.
Bioorg.Med.Chem.Lett., 29, 2019

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