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3TV4
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BU of 3tv4 by Molmil
Human B-Raf Kinase Domain in Complex with an Bromopyridine Benzamide Inhibitor
Descriptor: N-(6-amino-5-bromopyridin-3-yl)-2,6-difluoro-3-[(propylsulfonyl)amino]benzamide, Serine/threonine-protein kinase B-raf
Authors:Voegtli, W.C, Selby, L.T, Wu, W.-I.
Deposit date:2011-09-19
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
ACS Med Chem Lett, 2, 2011
3TV6
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BU of 3tv6 by Molmil
Human B-Raf Kinase Domain in Complex with a Methoxypyrazolopyridinyl Benzamide Inhibitor
Descriptor: 2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide, Serine/threonine-protein kinase B-raf
Authors:Voegtli, W.C, Sturgis, H.L, Wu, W.-I.
Deposit date:2011-09-19
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
ACS Med Chem Lett, 2, 2011

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数据于2024-11-06公开中

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