7BBA
 
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4QGY
 | | Camelid (llama) nanobody n25 (VHH) against type 6 secretion system TssM protein | | Descriptor: | nanobody n25, VH domain | | Authors: | Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E, Cambillau, C, Roussel, A. | | Deposit date: | 2014-05-26 | | Release date: | 2015-04-08 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody.
Plos One, 10, 2015
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4QLR
 | | Llama nanobody n02 raised against EAEC T6SS TssM | | Descriptor: | Llama nanobody n02 VH domain | | Authors: | Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E, Cambillau, C, Roussel, A. | | Deposit date: | 2014-06-13 | | Release date: | 2015-04-08 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody.
Plos One, 10, 2015
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3WXX
 | | Crystal Structure of a T3SS complex from Aeromonas hydrophila | | Descriptor: | AcrH, AopB, MAGNESIUM ION | | Authors: | Nguyen, V.S, Jobichen, C, Sivaraman, J, Henry, Y.K.M. | | Deposit date: | 2014-08-12 | | Release date: | 2015-10-14 | | Last modified: | 2015-11-11 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of AcrH-AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly
Structure, 23, 2015
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5M30
 | | Structure of TssK from T6SS EAEC in complex with nanobody nb18 | | Descriptor: | Anti-vesicular stomatitis virus N VHH, Type VI secretion protein | | Authors: | Nguyen, V.S, Cambillau, C, Spinelli, C, Desmyter, A, Legrand, P, Cascales, E. | | Deposit date: | 2016-10-13 | | Release date: | 2017-06-21 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
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4GQK
 | | Structure of Native VgrG1-ACD with ADP (no cations) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, VgrG protein | | Authors: | Nguyen, V.S, Spinelli, S, Derrez, E, Durand, E, Cambillau, C. | | Deposit date: | 2012-08-23 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structure of Native VgrG1-ACD with ADP (no cations)
To be Published
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7OJF
 | | CRYO-EM STRUCTURE OF SLYB13-BAMA FROM ESCHERICHIA COLI | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(~{E},3~{R})-3-dodecanoyloxytetradec-5-enoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(~{E},3~{R})-3-oxidanyltetradec-11-enoyl]amino]-4-[(~{E},3~{R})-3-oxidanyltetradec-5-enoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(~{E},3~{R})-3-tetradecanoyloxytetradec-7-enoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, GLYCEROL, ... | | Authors: | Nguyen, V.S, Remaut, H. | | Deposit date: | 2021-05-14 | | Release date: | 2022-07-27 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains
Nature, 2023
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7OJG
 | | CRYO-EM STRUCTURE OF UNDECAMERIC SLYB FROM ESCHERICHIA COLI K12 | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(~{E},3~{R})-3-dodecanoyloxytetradec-5-enoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(~{E},3~{R})-3-oxidanyltetradec-11-enoyl]amino]-4-[(~{E},3~{R})-3-oxidanyltetradec-5-enoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(~{E},3~{R})-3-tetradecanoyloxytetradec-7-enoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, GLYCEROL, ... | | Authors: | Nguyen, V.S, Remaut, H. | | Deposit date: | 2021-05-14 | | Release date: | 2022-08-03 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains
Nature, 2023
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5MWN
 | | Structure of the EAEC T6SS component TssK N-terminal domain in complex with llama nanobodies nbK18 and nbK27 | | Descriptor: | PHOSPHATE ION, Type VI secretion protein, llama nanobody raised against TssK, ... | | Authors: | Cambillau, C, Nguyen, V.S, Spinelli, S, Legrand, P. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-28 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
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5M2W
 | | Structure of nanobody nb18 raised against TssK from E. coli T6SS | | Descriptor: | Llama nanobody nb8 against TssK from T6SS, SULFATE ION | | Authors: | Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A. | | Deposit date: | 2016-10-13 | | Release date: | 2017-06-28 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
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5M2Y
 | | Structure of TssK C-terminal domain from E. coli T6SS | | Descriptor: | TssK C | | Authors: | Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A, Legrand, P. | | Deposit date: | 2016-10-13 | | Release date: | 2017-06-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
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4Y7L
 | | T6SS protein TssM C-terminal domain (869-1107) from EAEC | | Descriptor: | GLYCEROL, Type VI secretion protein IcmF, ZINC ION | | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | | Deposit date: | 2015-02-15 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Biogenesis and structure of a type VI secretion membrane core complex.
Nature, 523, 2015
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4Y7M
 | | T6SS protein TssM C-terminal domain (835-1129) from EAEC | | Descriptor: | Hi113 protein, SULFATE ION, Type VI secretion protein IcmF | | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | | Deposit date: | 2015-02-15 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Biogenesis and structure of a type VI secretion membrane core complex.
Nature, 523, 2015
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4Y7O
 | | T6SS protein TssM C-terminal domain (869-1107) from EAEC | | Descriptor: | Type VI secretion protein IcmF, Type VI secretion system protein VasD, ZINC ION | | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | | Deposit date: | 2015-02-15 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Biogenesis and structure of a type VI secretion membrane core complex.
Nature, 523, 2015
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6FVJ
 | | TesA a major thioesterase from Mycobacterium tuberculosis | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Thioesterase, ... | | Authors: | Cambillau, C, Nguyen, V.S, Canaan, S. | | Deposit date: | 2018-03-03 | | Release date: | 2018-10-24 | | Last modified: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.
J. Mol. Biol., 430, 2018
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6FW5
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5M38
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2NDK
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6T1W
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5YHN
 | | Solution structure of the LEKTI Domain 4 | | Descriptor: | cDNA FLJ60407, highly similar to Serine protease inhibitor Kazal-type 5 | | Authors: | Mok, Y.K, Ramesh, K. | | Deposit date: | 2017-09-29 | | Release date: | 2018-08-08 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity.
Structure, 26, 2018
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