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ChiLob 7/4 H2 HC-T219C/C224S Kappa LC-E123C/C214S F(ab')2
Descriptor:	Chilob 7/4 H2 heavy chain T219C/C224S, Chilob 7/4 H2 kappa chain E123C/C214S, SULFATE ION
Authors:	Elliott, I.G, Fisher, H, Tews, I.
Deposit date:	2023-07-17
Release date:	2025-03-05
Last modified:	2025-07-16
Method:	X-RAY DIFFRACTION (2.671 Å)
Cite:	Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism. Nat Commun, 16, 2025

ChiLob 7/4 H2 HC-K223C/C224S Kappa LC-C214S F(ab')2
Descriptor:	ChiLob 7/4 H2 heavy chain K223C/C224S, ChiLob 7/4 H2 kappa chain C214S, GLYCEROL
Authors:	Elliott, I, Fisher, H, Tews, I.
Deposit date:	2023-07-17
Release date:	2025-03-05
Last modified:	2025-07-16
Method:	X-RAY DIFFRACTION (1.93 Å)
Cite:	Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism. Nat Commun, 16, 2025