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Crystal structure of JNK3 in complex with a fragment molecule
Descriptor:	7-hexyl-3-methyl-8-sulfanylidene-9H-purine-2,6-dione, Mitogen-activated protein kinase 10
Authors:	Ahn, H.-C, Duong, M.T.H.
Deposit date:	2022-07-25
Release date:	2023-07-26
Last modified:	2024-05-29
Method:	X-RAY DIFFRACTION (2.48 Å)
Cite:	Crystal structure of JNK3 in complex with a fragment molecule To Be Published

SARS-CoV-2 Mac1 in complex with MDOLL-0169
Descriptor:	(1R,6R)-6-{[3-(methoxycarbonyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]carbamoyl}cyclohex-3-ene-1-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:	Wazir, S, Maksimainen, M, Lehtio, L.
Deposit date:	2023-08-17
Release date:	2024-04-17
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.74 Å)
Cite:	Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target. J.Med.Chem., 67, 2024

SARS-CoV-2 Mac1 in complex with MDOLL-0229
Descriptor:	(1R,2R)-2-{[3-(methoxycarbonyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic acid, GLYCEROL, Papain-like protease nsp3
Authors:	Wazir, S, Maksimainen, M, Lehtio, L.
Deposit date:	2023-08-17
Release date:	2024-04-24
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target. J.Med.Chem., 67, 2024