8C0E
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![BU of 8c0e by Molmil](/molmil-images/mine/8c0e) | The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase Wzz form a complex in vivo and in vitro | Descriptor: | ECA polysaccharide chain length modulation protein | Authors: | Weckener, M, Woodward, L.S, Clarke, B.R, Liu, H, Ward, P.N, Le Bas, A, Bhella, D, Whitfield, C, Naismith, J.H. | Deposit date: | 2022-12-16 | Release date: | 2023-04-19 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex. Open Biology, 13, 2023
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5NBZ
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![BU of 5nbz by Molmil](/molmil-images/mine/5nbz) | Wzz dodecamer fitted by MDFF to the Wzz experimental map from cryo-EM | Descriptor: | WzzB | Authors: | Ford, R.C, Kargas, V, Collins, R.F, Whitfield, C, Clarke, B.R, Siebert, A, Bond, P.J, Clare, D.K. | Deposit date: | 2017-03-02 | Release date: | 2017-04-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Full-length, Oligomeric Structure of Wzz Determined by Cryoelectron Microscopy Reveals Insights into Membrane-Bound States. Structure, 25, 2017
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6U4B
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![BU of 6u4b by Molmil](/molmil-images/mine/6u4b) | WbbM bifunctional glycosytransferase apo structure | Descriptor: | MAGNESIUM ION, WbbM protein | Authors: | Kimber, M.S, Mallette, E, Kamski-Hennekam, E.R, Gitalis, R. | Deposit date: | 2019-08-25 | Release date: | 2020-01-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family. Nat.Chem.Biol., 16, 2020
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2J58
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![BU of 2j58 by Molmil](/molmil-images/mine/2j58) | The structure of Wza | Descriptor: | HEXANE, N-OCTANE, OUTER MEMBRANE LIPOPROTEIN WZA, ... | Authors: | Dong, C, Naismith, J.H. | Deposit date: | 2006-09-12 | Release date: | 2006-11-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Wza the Translocon for E. Coli Capsular Polysaccharides Defines a New Class of Membrane Protein. Nature, 444, 2006
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4UW0
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![BU of 4uw0 by Molmil](/molmil-images/mine/4uw0) | |
5HNP
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![BU of 5hnp by Molmil](/molmil-images/mine/5hnp) | The structure of the kdo-capped saccharide binding subunit of the O-12 specific ABC transporter, Wzt | Descriptor: | ABC transporter, CHLORIDE ION | Authors: | Mallette, E, Mann, E, Whitfield, C, Kimber, M.S. | Deposit date: | 2016-01-18 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Klebsiella pneumoniae O12 ATP-binding Cassette (ABC) Transporter Recognizes the Terminal Residue of Its O-antigen Polysaccharide Substrate. J.Biol.Chem., 291, 2016
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5HNO
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![BU of 5hno by Molmil](/molmil-images/mine/5hno) | The structure of the kdo-capped saccharide binding subunit of the O-12 specific ABC transporter, Wzt | Descriptor: | ABC type transport system putative ATP binding protein, CHLORIDE ION | Authors: | Mallette, E, Mann, E, Whitfield, C, Kimber, M.S. | Deposit date: | 2016-01-18 | Release date: | 2016-03-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Klebsiella pneumoniae O12 ATP-binding Cassette (ABC) Transporter Recognizes the Terminal Residue of Its O-antigen Polysaccharide Substrate. J.Biol.Chem., 291, 2016
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4AZV
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![BU of 4azv by Molmil](/molmil-images/mine/4azv) | Co-crystal structure of WbdD and kinase inhibitor GW435821x. | Descriptor: | CHLORIDE ION, S-ADENOSYLMETHIONINE, SULFATE ION, ... | Authors: | Hagelueken, G, Huang, H, Naismith, J.H. | Deposit date: | 2012-06-26 | Release date: | 2012-09-26 | Last modified: | 2013-02-06 | Method: | X-RAY DIFFRACTION (3.291 Å) | Cite: | Structure of Wbdd; a Bifunctional Kinase and Methyltransferase that Regulates the Chain Length of the O Antigen in Escherichia Coli O9A. Mol.Microbiol., 86, 2012
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4AX8
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![BU of 4ax8 by Molmil](/molmil-images/mine/4ax8) | Medium resolution structure of the bifunctional kinase- methyltransferase WbdD | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, S-ADENOSYLMETHIONINE, ... | Authors: | Hagelueken, G, Huang, H, Naismith, J.H. | Deposit date: | 2012-06-11 | Release date: | 2012-10-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystallization, Dehydration and Experimental Phasing of Wbdd, a Bifunctional Kinase and Methyltransferase from Escherichia Coli O9A. Acta Crystallogr.,Sect.D, 68, 2012
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4AZT
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![BU of 4azt by Molmil](/molmil-images/mine/4azt) | Co-crystal structure of WbdD and kinase inhibitor LY294002. | Descriptor: | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, CHLORIDE ION, METHYLTRANSFERASE WBDD, ... | Authors: | Hagelueken, G, Huang, H, Naismith, J.H. | Deposit date: | 2012-06-26 | Release date: | 2012-09-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure of Wbdd; a Bifunctional Kinase and Methyltransferase that Regulates the Chain Length of the O Antigen in Escherichia Coli O9A. Mol.Microbiol., 86, 2012
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4AZS
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![BU of 4azs by Molmil](/molmil-images/mine/4azs) | High resolution (2.2 A) crystal structure of WbdD. | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, METHYLTRANSFERASE WBDD, ... | Authors: | Hagelueken, G, Huang, H, Naismith, J.H. | Deposit date: | 2012-06-26 | Release date: | 2012-09-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of Wbdd; a Bifunctional Kinase and Methyltransferase that Regulates the Chain Length of the O Antigen in Escherichia Coli O9A. Mol.Microbiol., 86, 2012
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4AZW
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![BU of 4azw by Molmil](/molmil-images/mine/4azw) | Crystal structure of monomeric WbdD. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... | Authors: | Hagelueken, G, Huang, H, Naismith, J.H. | Deposit date: | 2012-06-26 | Release date: | 2012-09-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structure of Wbdd; a Bifunctional Kinase and Methyltransferase that Regulates the Chain Length of the O Antigen in Escherichia Coli O9A. Mol.Microbiol., 86, 2012
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7NHR
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![BU of 7nhr by Molmil](/molmil-images/mine/7nhr) | |
7NIH
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![BU of 7nih by Molmil](/molmil-images/mine/7nih) | Wzc-K540M MgADP C8 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative transmembrane protein Wzc | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-12 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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7NHS
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![BU of 7nhs by Molmil](/molmil-images/mine/7nhs) | Wzc K540M C8 | Descriptor: | Putative transmembrane protein Wzc | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-11 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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7NII
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![BU of 7nii by Molmil](/molmil-images/mine/7nii) | Wzc-K540M MgADP C1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative transmembrane protein Wzc | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-12 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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7NI2
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![BU of 7ni2 by Molmil](/molmil-images/mine/7ni2) | Wzc-K540M-4YE C8 | Descriptor: | Tyrosine-protein kinase | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-11 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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7NIB
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![BU of 7nib by Molmil](/molmil-images/mine/7nib) | Wzc-K540M-4YE C1 | Descriptor: | Tyrosine-protein kinase | Authors: | Naismith, J.H, Liu, J.W, Yang, Y. | Deposit date: | 2021-02-11 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | The molecular basis of regulation of bacterial capsule assembly by Wzc. Nat Commun, 12, 2021
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