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8DLD
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BU of 8dld by Molmil
Crystal structure of chalcone-isomerase like protein from Physcomitrella patens (PpCHIL-A)
Descriptor: Chalcone-flavonone isomerase family protein
Authors:Wolf Saxon, E, Moorman, C, Castro, A, Ruiz, A, Mallari, J.P, Burke, J.R.
Deposit date:2022-07-07
Release date:2023-05-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Regulatory ligand binding in plant chalcone isomerase-like (CHIL) proteins.
J.Biol.Chem., 299, 2023
8DLC
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BU of 8dlc by Molmil
Crystal structure of chalcone-isomerase like protein from Vitis vinifera (VvCHIL)
Descriptor: Chalcone-flavonone isomerase family protein
Authors:Wolf Saxon, E, Moorman, C, Castro, A, Ruiz, A, Mallari, J.P, Burke, J.R.
Deposit date:2022-07-07
Release date:2023-05-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Regulatory ligand binding in plant chalcone isomerase-like (CHIL) proteins.
J.Biol.Chem., 299, 2023
6BVE
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BU of 6bve by Molmil
Triosephosphate isomerase of Synechocystis in complex with 2-Phosphoglycolic acid
Descriptor: 2-PHOSPHOGLYCOLIC ACID, SODIUM ION, Triosephosphate isomerase
Authors:Jimenez-Sandoval, P, Castro-Torres, E, Brieba, L.G.
Deposit date:2017-12-12
Release date:2018-12-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis for the Limited Response to Oxidative and Thiol-Conjugating Agents by Triosephosphate Isomerase From the Photosynthetic BacteriaSynechocystis.
Front Mol Biosci, 5, 2018
4HX5
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BU of 4hx5 by Molmil
Crystal structure of 11 beta-HSD1 in complex with SAR184841
Descriptor: 4-[5-(4-tert-butylpiperazin-1-yl)pyridin-2-yl]-N-[(1R,2S,3S,5S,7s)-5-carbamoyltricyclo[3.3.1.1~3,7~]dec-2-yl]-3,4-dihydroquinoxaline-1(2H)-carboxamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Loenze, P, Schimanski-Breves, S, Engel, C.K.
Deposit date:2012-11-09
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Discovery of SAR184841, a potent and long-lasting inhibitor of 11beta-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D
Bioorg.Med.Chem.Lett., 23, 2013
3G49
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BU of 3g49 by Molmil
N-(Pyridin-2-yl) Arylsulfonamide Inhibitors of 11b-Hydroxysteroid Dehydrogenase Type 1: Discovery of PF-915275
Descriptor: 11-beta-hydroxysteroid dehydrogenase 1, 2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Pauly, T.A.
Deposit date:2009-02-03
Release date:2009-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275.
Bioorg.Med.Chem.Lett., 19, 2009

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