1P13
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p13 by Molmil](/molmil-images/mine/1p13) | Crystal Structure of the Src SH2 Domain Complexed with Peptide (SDpYANFK) | Descriptor: | CACODYLATE ION, Peptide, Proto-oncogene tyrosine-protein kinase Src | Authors: | Sonnenburg, E.D, Bilwes, A, Hunter, T, Noel, J.P. | Deposit date: | 2003-04-11 | Release date: | 2003-08-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region. Biochemistry, 42, 2003
|
|
1SUS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sus by Molmil](/molmil-images/mine/1sus) | Crystal structure of alfalfa feruoyl coenzyme A 3-O-methyltransferase | Descriptor: | CALCIUM ION, Caffeoyl-CoA O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Ferrer, J.-L, Zubieta, C, Dixon, R.A, Noel, J.P. | Deposit date: | 2004-03-26 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of Alfalfa Caffeoyl Coenzyme A 3-O-Methyltransferase Plant Physiol., 137, 2005
|
|
1U0U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u0u by Molmil](/molmil-images/mine/1u0u) | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: Pine stilbene synthase structure | Descriptor: | Dihydropinosylvin synthase | Authors: | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | Deposit date: | 2004-07-14 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11, 2004
|
|
1HXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hxc by Molmil](/molmil-images/mine/1hxc) | CRYSTAL STRUCTURE OF TEAS C440W | Descriptor: | 1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE PHOSPHONIC ACID, 5-EPI-ARISTOLOCHENE SYNTHASE | Authors: | Starks, C.S, Rising, K.A, Chappell, J, Noel, J.P. | Deposit date: | 2001-01-12 | Release date: | 2003-06-24 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Single Active Site Mutations Change the Specificity of a Sesquiterpene Cyclase To be Published
|
|
1D6I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1d6i by Molmil](/molmil-images/mine/1d6i) | CHALCONE SYNTHASE (H303Q MUTANT) | Descriptor: | CHALCONE SYNTHASE, SULFATE ION | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 1999-10-13 | Release date: | 2000-02-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
|
|
1HXA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hxa by Molmil](/molmil-images/mine/1hxa) | CRYSTAL STRUCTURE OF TEAS W273S FORM 2 | Descriptor: | 1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE PHOSPHONIC ACID, 5-EPI-ARISTOLOCHENE SYNTHASE, MAGNESIUM ION | Authors: | Starks, C.S, Rising, K.A, Chappell, J, Noel, J.P. | Deposit date: | 2001-01-12 | Release date: | 2003-06-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Single Active Site Mutations Change the Specificity of a Sesquiterpene Cyclase To be Published
|
|
1HX9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hx9 by Molmil](/molmil-images/mine/1hx9) | CRYSTAL STRUCTURE OF TEAS W273S FORM 1 | Descriptor: | 1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE PHOSPHONIC ACID, 5-EPI-ARISTOLOCHENE SYNTHASE, MAGNESIUM ION | Authors: | Starks, C.S, Rising, K.A, Chappell, J, Noel, J.P. | Deposit date: | 2001-01-12 | Release date: | 2003-06-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Single Active Site Mutations Change the Specificity of a Sesquiterpene Cyclase To be Published
|
|
1HXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hxg by Molmil](/molmil-images/mine/1hxg) | |
1I88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i88 by Molmil](/molmil-images/mine/1i88) | CHALCONE SYNTHASE (G256V) | Descriptor: | CHALCONE SYNTHASE 2, SULFATE ION | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
|
|
1D6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1d6f by Molmil](/molmil-images/mine/1d6f) | CHALCONE SYNTHASE C164A MUTANT | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHALCONE SYNTHASE, SULFATE ION | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 1999-10-13 | Release date: | 2000-02-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
|
|
1D6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1d6h by Molmil](/molmil-images/mine/1d6h) | CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA) | Descriptor: | CHALCONE SYNTHASE, COENZYME A, SULFATE ION | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 1999-10-13 | Release date: | 2000-02-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
|
|
1I52
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i52 by Molmil](/molmil-images/mine/1i52) | CRYSTAL STRUCTURE OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHASE, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, M, Cane, D.E, Noel, J.P. | Deposit date: | 2001-02-23 | Release date: | 2001-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat.Struct.Biol., 8, 2001
|
|
1I86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i86 by Molmil](/molmil-images/mine/1i86) | CHALCONE SYNTHASE, G256A MUTANT | Descriptor: | CHALCONE SYNTHASE 2, SULFATE ION | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
|
|
1I89
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i89 by Molmil](/molmil-images/mine/1i89) | Chalcone synthase (G256L) | Descriptor: | CHALCONE SYNTHASE 2 | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
|
|
1I8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i8b by Molmil](/molmil-images/mine/1i8b) | Chalcone synthase (G256F) | Descriptor: | CHALCONE SYNTHASE 2 | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
|
|
1INI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ini by Molmil](/molmil-images/mine/1ini) | CRYSTAL STRUCTURE OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHETASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS, COMPLEXED WITH CDP-ME AND MG2+ | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHETASE, MAGNESIUM ION | Authors: | Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, A, Cane, D.E, Noel, J.P. | Deposit date: | 2001-05-14 | Release date: | 2001-11-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat.Struct.Biol., 8, 2001
|
|
1INJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1inj by Molmil](/molmil-images/mine/1inj) | CRYSTAL STRUCTURE OF THE APO FORM OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHETASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHETASE, CALCIUM ION | Authors: | Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, A, Cane, D.E, Noel, J.P. | Deposit date: | 2001-05-14 | Release date: | 2001-07-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat.Struct.Biol., 8, 2001
|
|
1JEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jep by Molmil](/molmil-images/mine/1jep) | Chalcone Isomerase Complexed with 4'-hydroxyflavanone | Descriptor: | 2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, CHALCONE--FLAVONONE ISOMERASE 1, SULFATE ION | Authors: | Jez, J.M, Noel, J.P. | Deposit date: | 2001-06-18 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences. J.Biol.Chem., 277, 2002
|
|
1JWX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jwx by Molmil](/molmil-images/mine/1jwx) | Chalcone Synthase--F215S mutant | Descriptor: | CHALCONE SYNTHASE 2 | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-09-05 | Release date: | 2002-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity. Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
5UCO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uco by Molmil](/molmil-images/mine/5uco) | |
5UC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uc5 by Molmil](/molmil-images/mine/5uc5) | Chalcone synthase from Malus domestica | Descriptor: | CHS2 chalcone synthase | Authors: | Stewart Jr, C.E, Noel, J.P. | Deposit date: | 2016-12-21 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Molecular architectures of benzoic acid-specific type III polyketide synthases. Acta Crystallogr D Struct Biol, 73, 2017
|
|
5WL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wl8 by Molmil](/molmil-images/mine/5wl8) | Crystal structure of chalcone isomerase engineered from ancestral inference (epR4) | Descriptor: | Engineered Chalcone Isomerase epR4, FORMIC ACID | Authors: | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | Deposit date: | 2017-07-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Evolution of chalcone isomerase from a noncatalytic ancestor. Nat. Chem. Biol., 14, 2018
|
|
5WKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wkr by Molmil](/molmil-images/mine/5wkr) | Crystal structure of chalcone isomerase engineered from ancestral inference complexed with naringenin (ancCC) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Engineered Chalcone Isomerase ancCC, ... | Authors: | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | Deposit date: | 2017-07-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Evolution of chalcone isomerase from a noncatalytic ancestor. Nat. Chem. Biol., 14, 2018
|
|
5WL4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wl4 by Molmil](/molmil-images/mine/5wl4) | Crystal structure of chalcone isomerase engineered from ancestral inference (ancR3) | Descriptor: | Engineered Chalcone Isomerase ancR3, FORMIC ACID | Authors: | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | Deposit date: | 2017-07-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Evolution of chalcone isomerase from a noncatalytic ancestor. Nat. Chem. Biol., 14, 2018
|
|
5W8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w8q by Molmil](/molmil-images/mine/5w8q) | |