7VH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vh5 by Molmil](/molmil-images/mine/7vh5) | Cryo-EM structure of the hexameric plasma membrane H+-ATPase in the autoinhibited state (pH 7.4, C1 symmetry) | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Plasma membrane ATPase 1, SPHINGOSINE | Authors: | Zhao, P, Zhao, C, Chen, D, Yun, C, Li, H, Bai, L. | Deposit date: | 2021-09-21 | Release date: | 2021-11-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure and activation mechanism of the hexameric plasma membrane H + -ATPase. Nat Commun, 12, 2021
|
|
7VH6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vh6 by Molmil](/molmil-images/mine/7vh6) | Cryo-EM structure of the hexameric plasma membrane H+-ATPase in the active state (pH 6.0, BeF3-, conformation 1, C1 symmetry) | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, BERYLLIUM TRIFLUORIDE ION, Plasma membrane ATPase 1 | Authors: | Zhao, P, Zhao, C, Chen, D, Yun, C, Li, H, Bai, L. | Deposit date: | 2021-09-21 | Release date: | 2021-11-24 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure and activation mechanism of the hexameric plasma membrane H + -ATPase. Nat Commun, 12, 2021
|
|
8GQD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gqd by Molmil](/molmil-images/mine/8gqd) | Complex Structure of Arginine Kinase McsB and McsA from Staphylococcus aureus | Descriptor: | Protein-arginine kinase, Protein-arginine kinase activator protein, ZINC ION | Authors: | Lu, K, Luo, B, Tao, X, Li, H, Xie, Y, Zhao, Z, Xia, W, Su, Z, Mao, Z. | Deposit date: | 2022-08-30 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Complex Structure and Activation Mechanism of Arginine Kinase McsB by McsA To Be Published
|
|
2H6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h6q by Molmil](/molmil-images/mine/2h6q) | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | Descriptor: | Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5 | Authors: | Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-06-01 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat.Struct.Mol.Biol., 13, 2006
|
|
2H68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h68 by Molmil](/molmil-images/mine/2h68) | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | Descriptor: | WD-repeat protein 5 | Authors: | Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-30 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat.Struct.Mol.Biol., 13, 2006
|
|
2H6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h6k by Molmil](/molmil-images/mine/2h6k) | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | Descriptor: | Histone H3 K4-Me 9-residue peptide, WD-repeat protein 5 | Authors: | Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-31 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat.Struct.Mol.Biol., 13, 2006
|
|
2GJW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gjw by Molmil](/molmil-images/mine/2gjw) | RNA Recognition and Cleavage by an Splicing Endonuclease | Descriptor: | 5'-R(*AP*GP*GP*UP*CP*GP*C)-3', 5'-R(*GP*CP*GP*AP*CP*CP*GP*AP*CP*CP*AP*(DU)P*AP*GP*CP*UP*GP*CP*A)-3', 5'-R(*UP*GP*CP*AP*GP*CP*GP*GP*UP*CP*AP*(A23))-3', ... | Authors: | Xue, S, Calvin, K, Li, H. | Deposit date: | 2006-03-31 | Release date: | 2006-09-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | RNA Recognition and Cleavage by an Splicing Endonuclease Science, 312, 2006
|
|
2H6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h6n by Molmil](/molmil-images/mine/2h6n) | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | Descriptor: | Histone H3 K4-Me2 9-residue peptide, WD-repeat protein 5 | Authors: | Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-31 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat.Struct.Mol.Biol., 13, 2006
|
|
7BZJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bzj by Molmil](/molmil-images/mine/7bzj) | The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors | Descriptor: | Leucine--tRNA ligase, [(1~{R},5~{R},6~{S},8~{R})-8-(6-aminopurin-9-yl)-4'-[(~{R})-oxidanyl-[4-(2-oxidanylidenepropylsulfanyl)phenyl]methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,7'-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-6-yl]methoxy-tris(oxidanyl)phosphanium | Authors: | Liu, R.J, Li, H, Wang, E.D, Zhou, H. | Deposit date: | 2020-04-28 | Release date: | 2020-12-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors. Bioorg.Med.Chem., 29, 2021
|
|
2G2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2g2c by Molmil](/molmil-images/mine/2g2c) | |
2EWC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ewc by Molmil](/molmil-images/mine/2ewc) | Structure of hypothetical protein from Streptococcus pyogenes M1 GAS, member of highly conserved yjgF family of proteins | Descriptor: | GLYCEROL, conserved hypothetical protein | Authors: | Nocek, B, Li, H, Clancy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-11-02 | Release date: | 2005-12-13 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of hypothetical protein from Streptococcus pyogenes M1 GAS, member of highly conserved yjgF family of proteins To be Published
|
|
2EY4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ey4 by Molmil](/molmil-images/mine/2ey4) | Crystal Structure of a Cbf5-Nop10-Gar1 Complex | Descriptor: | Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ZINC ION, ... | Authors: | Rashid, R, Liang, B, Li, H, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2005-11-09 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita. Mol.Cell, 21, 2006
|
|
2FHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fhg by Molmil](/molmil-images/mine/2fhg) | Crystal Structure of Mycobacterial Tuberculosis Proteasome | Descriptor: | 20S proteasome, alpha and beta subunits, proteasome, ... | Authors: | Hu, G, Lin, G, Wang, M, Dick, L, Xu, R.M, Nathan, C, Li, H. | Deposit date: | 2005-12-23 | Release date: | 2006-02-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate. Mol.Microbiol., 59, 2006
|
|
2FL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fl0 by Molmil](/molmil-images/mine/2fl0) | Oxidized (All ferric) form of the Azotobacter vinelandii bacterioferritin | Descriptor: | Bacterioferritin, FE (II) ION, MAGNESIUM ION, ... | Authors: | Swartz, L, Kunchinskas, K, Li, H, Poulos, T.L, Lanzilotta, W.N. | Deposit date: | 2006-01-05 | Release date: | 2006-04-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Redox-Dependent Structural Changes in the Azotobacter vinelandii Bacterioferritin: New Insights into the Ferroxidase and Iron Transport Mechanism(,). Biochemistry, 45, 2006
|
|
2GUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gup by Molmil](/molmil-images/mine/2gup) | Structural Genomics, the crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ROK family protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Tan, K, Li, H, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-05-01 | Release date: | 2006-05-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | The crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose To be Published
|
|
2GS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gs8 by Molmil](/molmil-images/mine/2gs8) | Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, mevalonate pyrophosphate decarboxylase | Authors: | Cuff, M.E, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-04-25 | Release date: | 2006-06-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of mevalonate pyrophosphate decarboxylase from Streptococcus pyogenes To be Published
|
|
2FCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fck by Molmil](/molmil-images/mine/2fck) | Structure of a putative ribosomal-protein-serine acetyltransferase from Vibrio cholerae. | Descriptor: | GLYCEROL, NITRATE ION, ribosomal-protein-serine acetyltransferase, ... | Authors: | Cuff, M.E, Li, H, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-12 | Release date: | 2006-02-28 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of an acetyltransferase protein from Vibrio cholerae strain N16961. Proteins, 69, 2007
|
|
4ILR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ilr by Molmil](/molmil-images/mine/4ilr) | |
5UFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ufh by Molmil](/molmil-images/mine/5ufh) | The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 | Descriptor: | GLYCEROL, LacI-type transcriptional regulator, NITRATE ION | Authors: | Tan, K, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-04 | Release date: | 2017-01-18 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 To Be Published
|
|
5UHJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uhj by Molmil](/molmil-images/mine/5uhj) | The crystal structure of a natural product biosynthetic enzyme from Streptomyces sp. CB03234 | Descriptor: | FORMIC ACID, Glyoxalase/bleomycin resisance protein/dioxygenase | Authors: | Tan, K, Li, H, Endres, M, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2017-01-11 | Release date: | 2017-01-25 | Last modified: | 2020-09-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The crystal structure of a natural product biosynthetic enzyme from Streptomyces sp. CB03234 To Be Published
|
|
5UJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ujm by Molmil](/molmil-images/mine/5ujm) | Structure of the active form of human Origin Recognition Complex and its ATPase motor module | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ... | Authors: | Tocilj, A, On, K, Yuan, Z, Sun, J, Elkayam, E, Li, H, Stillman, B, Joshua-Tor, L. | Deposit date: | 2017-01-18 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (18 Å) | Cite: | Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
|
|
5UOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uob by Molmil](/molmil-images/mine/5uob) | Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2R)-2-(methylamino)propyl]benzonitrile, CHLORIDE ION, ... | Authors: | Chreifi, G, Li, H, Poulos, T.L. | Deposit date: | 2017-01-31 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
|
|
5UJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ujp by Molmil](/molmil-images/mine/5ujp) | The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Glyoxalase/bleomycin resisance protein/dioxygenase | Authors: | Tan, K, Li, H, Endres, M, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2017-01-18 | Release date: | 2017-02-22 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234 To Be Published
|
|
4ILM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ilm by Molmil](/molmil-images/mine/4ilm) | CRISPR RNA Processing endoribonuclease | Descriptor: | CRISPR-associated endoribonuclease Cas6 2, RNA (5'-R(*GP*CP*UP*AP*AP*UP*CP*UP*AP*CP*UP*AP*UP*AP*GP*A)-3') | Authors: | Shao, Y, Li, H. | Deposit date: | 2012-12-31 | Release date: | 2013-03-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.068 Å) | Cite: | Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6. Structure, 21, 2013
|
|
4ILL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ill by Molmil](/molmil-images/mine/4ill) | |