1GE4
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1IP5
| G105A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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1IP7
| G129A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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1IP2
| G48A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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1IX0
| I59A-3SS human lysozyme | Descriptor: | SODIUM ION, lysozyme | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2002-06-06 | Release date: | 2003-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Buried water molecules contribute to the conformational stability of a protein PROTEIN ENG., 16, 2003
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1GDX
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1GDW
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1GE0
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1GE3
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5BR7
| Structure of UDP-galactopyranose mutase from Corynebacterium diphtheriae in complex with citrate ion | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Wangkanont, K, Kiessling, L.L, Forest, K.T. | Deposit date: | 2015-05-29 | Release date: | 2016-06-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Conformational Control of UDP-Galactopyranose Mutase Inhibition. Biochemistry, 56, 2017
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1IP6
| G127A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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1IP4
| G72A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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1IP3
| G68A HUMAN LYSOZYME | Descriptor: | LYSOZYME C, SODIUM ION, SULFATE ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2001-04-20 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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7D5M
| Crystal structure of inositol dehydrogenase homolog complexed with NAD+ from Azotobacter vinelandii | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Oxidoreductase | Authors: | Fukano, K, Ono, T, Suzuki, M, Takenoya, M, Ito, S, Sasaki, Y, Yajima, S. | Deposit date: | 2020-09-27 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of inositol dehydrogenase complexed with NAD+ from Azotobacter vinelandii To Be Published
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7D5N
| Crystal structure of inositol dehydrogenase homolog complexed with NADH and myo-inositol from Azotobacter vinelandii | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Oxidoreductase | Authors: | Fukano, K, Ono, T, Suzuki, M, Takenoya, M, Ito, S, Sasaki, Y, Yajima, S. | Deposit date: | 2020-09-27 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of inositol dehydrogenase complexed with NADH and myo-inositol from Azotobacter vinelandii To Be Published
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1UCL
| Mutants of RNase Sa | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | Deposit date: | 2003-04-15 | Release date: | 2003-09-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent J.Biol.Chem., 278, 2003
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1X1P
| Crystal structure of Tk-RNase HII(1-197)-A(28-42) | Descriptor: | Ribonuclease HII | Authors: | Takano, K, Endo, S, Mukaiyama, A, Chon, H, Matsumura, H, Koga, Y, Kanaya, S. | Deposit date: | 2005-04-11 | Release date: | 2006-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of amyloid beta fragments in aqueous environments Febs J., 273, 2006
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1UCI
| Mutants of RNase Sa | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | Deposit date: | 2003-04-15 | Release date: | 2003-09-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent J.Biol.Chem., 278, 2003
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2MEE
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1OUA
| CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE I56T MUTANT | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Funahashi, J, Yamagata, Y, Ogasahara, K, Yutani, K. | Deposit date: | 1996-08-23 | Release date: | 1997-02-12 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure, stability, and folding process of amyloidogenic mutant human lysozyme. J.Biochem.(Tokyo), 120, 1996
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4WMQ
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4WMY
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7XLP
| MEK1 bound to DS03090629 | Descriptor: | (1~{R},3~{S})-3-[[6-[2-chloranyl-4-(4-methylpyrimidin-2-yl)oxy-phenyl]-3-methyl-1~{H}-indazol-4-yl]oxy]cyclohexan-1-amine, CALCIUM ION, DIMETHYL SULFOXIDE, ... | Authors: | Kishikawa, S, Takano, K, Ubukata, O, Hanzawa, H. | Deposit date: | 2022-04-22 | Release date: | 2023-03-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma. Mol.Cancer Ther., 22, 2023
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7XNC
| MEK1 bound to DS94070624 | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Kishikawa, S, Takano, K, Ubukata, O, Hanzawa, H. | Deposit date: | 2022-04-28 | Release date: | 2023-03-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma. Mol.Cancer Ther., 22, 2023
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1YAO
| CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: CALORIMETRIC STUDIES AND X-RAY STRUCTURAL ANALYSIS OF THE FIVE ISOLEUCINE TO VALINE MUTANTS | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kaneda, H, Fujii, S, Takano, K, Ogasahara, K, Kanaya, E, Kikuchi, M, Oobatake, M, Yutani, K. | Deposit date: | 1995-09-29 | Release date: | 1996-04-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrophobic residues to the stability of human lysozyme: calorimetric studies and X-ray structural analysis of the five isoleucine to valine mutants. J.Mol.Biol., 254, 1995
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